Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001010854                                                           16    7355
XP_005267424                                                           16    7355
XP_006720122                                                           16    7355
XP_006720121                                                           16    7355
NP_079066                                                              15    9605
NP_001278268                                                           15    9605
NP_115827                                                              15    9605
XP_006721370                                                           15    9605
XP_006721369                                                           15    9605
XP_006721368                                                           15    9605
XP_006721367                                                           15    9605
XP_006721366                                                           15    9605
XP_006721365                                                           15    9605
XP_006716542                                                           15    9605
XP_006716541                                                           15    9605
XP_006716540                                                           15    9605
XP_006716539                                                           15    9605
XP_006716538                                                           15    9605
XP_005251368                                                           15    9605
XP_006716537                                                           15    9605
XP_006716536                                                           15    9605
XP_005251364                                                           15    9605
XP_006716535                                                           15    9605
XP_006716534                                                           15    9605
XP_006716533                                                           15    9605
XP_006716532                                                           15    9605
XP_005251363                                                           15    9605
XP_005251362                                                           15    9605
>NP_001010854
          Length = 843

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKVASRLQS 9
           S+VAS LQS
Sbjct: 673 SEVASSLQS 681
>XP_005267424
          Length = 656

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKVASRLQS 9
           S+VAS LQS
Sbjct: 486 SEVASSLQS 494
>XP_006720122
          Length = 820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKVASRLQS 9
           S+VAS LQS
Sbjct: 650 SEVASSLQS 658
>XP_006720121
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKVASRLQS 9
           S+VAS LQS
Sbjct: 681 SEVASSLQS 689
>NP_079066
          Length = 1221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 855 NKIASKLQ 862
>NP_001278268
          Length = 876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 510 NKIASKLQ 517
>NP_115827
          Length = 714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKVASRLQS 9
           S+VAS LQS
Sbjct: 451 SEVASGLQS 459
>XP_006721370
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKVASRLQS 9
           S+VAS LQS
Sbjct: 451 SEVASGLQS 459
>XP_006721369
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKVASRLQS 9
           S+VAS LQS
Sbjct: 451 SEVASGLQS 459
>XP_006721368
          Length = 533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKVASRLQS 9
           S+VAS LQS
Sbjct: 451 SEVASGLQS 459
>XP_006721367
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKVASRLQS 9
           S+VAS LQS
Sbjct: 451 SEVASGLQS 459
>XP_006721366
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKVASRLQS 9
           S+VAS LQS
Sbjct: 366 SEVASGLQS 374
>XP_006721365
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKVASRLQS 9
           S+VAS LQS
Sbjct: 366 SEVASGLQS 374
>XP_006716542
          Length = 1029

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 890 NKIASKLQ 897
>XP_006716541
          Length = 1032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 890 NKIASKLQ 897
>XP_006716540
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 713 NKIASKLQ 720
>XP_006716539
          Length = 1152

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 890 NKIASKLQ 897
>XP_006716538
          Length = 1170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 804 NKIASKLQ 811
>XP_005251368
          Length = 1185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 819 NKIASKLQ 826
>XP_006716537
          Length = 1205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 839 NKIASKLQ 846
>XP_006716536
          Length = 1212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 846 NKIASKLQ 853
>XP_005251364
          Length = 1212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 846 NKIASKLQ 853
>XP_006716535
          Length = 1220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 854 NKIASKLQ 861
>XP_006716534
          Length = 1220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 854 NKIASKLQ 861
>XP_006716533
          Length = 1220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 854 NKIASKLQ 861
>XP_006716532
          Length = 1223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 857 NKIASKLQ 864
>XP_005251363
          Length = 1248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 882 NKIASKLQ 889
>XP_005251362
          Length = 1256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKVASRLQ 8
           +K+AS+LQ
Sbjct: 890 NKIASKLQ 897
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.104    0.219 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 207,155
Number of extensions: 251
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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