Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001155973                                                           22      79
NP_001020014                                                           22      79
NP_055903                                                              22      79
NP_001092882                                                           17    2528
NP_006757                                                              17    2528
NP_001092883                                                           17    2528
XP_005273706                                                           17    2528
NP_001263200                                                           17    4312
NP_002325                                                              17    4312
NP_001263201                                                           17    4312
NP_003916                                                              17    4312
NP_001263199                                                           17    4312
NP_001017924                                                           17    4312
NP_001271152                                                           17    4312
XP_006718294                                                           17    4312
XP_005252980                                                           17    4312
NP_001701                                                              16    5631
NP_116165                                                              16    5631
NP_001093591                                                           16    5631
NP_001093590                                                           16    5631
NP_066022                                                              16    5631
NP_002888                                                              16    5631
NP_058520                                                              16    5631
XP_006726463                                                           16    5631
XP_005269685                                                           16    5631
XP_005269684                                                           16    5631
XP_005269679                                                           16    5631
XP_006714837                                                           16    5631
XP_006712963                                                           16    5631
XP_006712738                                                           16    5631
XP_006712737                                                           16    5631
XP_006712736                                                           16    5631
XP_005246797                                                           16    5631
XP_005246798                                                           16    5631
XP_005246796                                                           16    5631
XP_006712735                                                           16    5631
XP_005246795                                                           16    5631
XP_005246794                                                           16    5631
XP_006712734                                                           16    5631
XP_006710204                                                           16    5631
NP_001032401                                                           16    5631
NP_055508                                                              16    5631
NP_008958                                                              15    9605
NP_005392                                                              15    9605
NP_149973                                                              15    9605
NP_001070817                                                           15    9605
NP_071918                                                              15    9605
NP_064601                                                              15    9605
NP_775922                                                              15    9605
XP_005260203                                                           15    9605
XP_005254649                                                           15    9605
XP_005254648                                                           15    9605
XP_005247133                                                           15    9605
XP_005245478                                                           15    9605
XP_005245477                                                           15    9605
XP_005245476                                                           15    9605
XP_005245475                                                           15    9605
>NP_001155973
          Length = 1833

 Score = 22.3 bits (46), Expect =    79
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SKSSNANWP 9
            SKSSNA+WP
Sbjct: 1469 SKSSNASWP 1477
>NP_001020014
          Length = 1029

 Score = 22.3 bits (46), Expect =    79
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SKSSNANWP 9
           SKSSNA+WP
Sbjct: 665 SKSSNASWP 673
>NP_055903
          Length = 1723

 Score = 22.3 bits (46), Expect =    79
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SKSSNANWP 9
            SKSSNA+WP
Sbjct: 1359 SKSSNASWP 1367
>NP_001092882
          Length = 2004

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KSSNANWP 9
           KSS ++WP
Sbjct: 446 KSSTSDWP 453
>NP_006757
          Length = 2004

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KSSNANWP 9
           KSS ++WP
Sbjct: 446 KSSTSDWP 453
>NP_001092883
          Length = 2004

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KSSNANWP 9
           KSS ++WP
Sbjct: 446 KSSTSDWP 453
>XP_005273706
          Length = 1997

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KSSNANWP 9
           KSS ++WP
Sbjct: 439 KSSTSDWP 446
>NP_001263200
          Length = 572

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SKSSNANW 8
           ++S+N+NW
Sbjct: 169 NQSNNSNW 176
>NP_002325
          Length = 1905

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   SSNANWP 9
           SSN  WP
Sbjct: 899 SSNLTWP 905
>NP_001263201
          Length = 540

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SKSSNANW 8
           ++S+N+NW
Sbjct: 169 NQSNNSNW 176
>NP_003916
          Length = 580

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SKSSNANW 8
           ++S+N+NW
Sbjct: 169 NQSNNSNW 176
>NP_001263199
          Length = 574

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SKSSNANW 8
           ++S+N+NW
Sbjct: 169 NQSNNSNW 176
>NP_001017924
          Length = 550

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SKSSNANWP 9
           SKS   NWP
Sbjct: 167 SKSVFLNWP 175
>NP_001271152
          Length = 560

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SKSSNANWP 9
           SKS   NWP
Sbjct: 167 SKSVFLNWP 175
>XP_006718294
          Length = 1808

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   SSNANWP 9
           SSN  WP
Sbjct: 899 SSNLTWP 905
>XP_005252980
          Length = 1809

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   SSNANWP 9
           SSN  WP
Sbjct: 899 SSNLTWP 905
>NP_001701
          Length = 764

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   SSNANW 8
           SSNA+W
Sbjct: 329 SSNADW 334
>NP_116165
          Length = 2540

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   SKSSNANWP 9
           SKS    WP
Sbjct: 101 SKSKQIQWP 109
>NP_001093591
          Length = 765

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SKSSNAN 7
           SKSSN+N
Sbjct: 241 SKSSNSN 247
>NP_001093590
          Length = 811

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SKSSNAN 7
           SKSSN+N
Sbjct: 287 SKSSNSN 293
>NP_066022
          Length = 2564

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    KSSNANW 8
            KSSN +W
Sbjct: 2436 KSSNRSW 2442
>NP_002888
          Length = 403

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SKSSNANW 8
          S SSN+ W
Sbjct: 49 SSSSNSGW 56
>NP_058520
          Length = 406

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SKSSNANW 8
          S SSN+ W
Sbjct: 49 SSSSNSGW 56
>XP_006726463
          Length = 119

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SKSSNANW 8
          S +SNA W
Sbjct: 16 SSNSNARW 23
>XP_005269685
          Length = 1700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   SKSSNANWP 9
           SKS    WP
Sbjct: 101 SKSKQIQWP 109
>XP_005269684
          Length = 2032

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   SKSSNANWP 9
           SKS    WP
Sbjct: 101 SKSKQIQWP 109
>XP_005269679
          Length = 2502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   SKSSNANWP 9
           SKS    WP
Sbjct: 101 SKSKQIQWP 109
>XP_006714837
          Length = 628

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   SSNANWP 9
           ++NA WP
Sbjct: 587 AANARWP 593
>XP_006712963
          Length = 119

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SKSSNANW 8
          S +SNA W
Sbjct: 16 SSNSNARW 23
>XP_006712738
          Length = 403

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SKSSNANW 8
          S SSN+ W
Sbjct: 30 SSSSNSGW 37
>XP_006712737
          Length = 405

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SKSSNANW 8
          S SSN+ W
Sbjct: 51 SSSSNSGW 58
>XP_006712736
          Length = 408

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SKSSNANW 8
          S SSN+ W
Sbjct: 51 SSSSNSGW 58
>XP_005246797
          Length = 419

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SKSSNANW 8
          S SSN+ W
Sbjct: 49 SSSSNSGW 56
>XP_005246798
          Length = 419

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SKSSNANW 8
          S SSN+ W
Sbjct: 46 SSSSNSGW 53
>XP_005246796
          Length = 420

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SKSSNANW 8
          S SSN+ W
Sbjct: 47 SSSSNSGW 54
>XP_006712735
          Length = 421

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SKSSNANW 8
          S SSN+ W
Sbjct: 51 SSSSNSGW 58
>XP_005246795
          Length = 421

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SKSSNANW 8
          S SSN+ W
Sbjct: 48 SSSSNSGW 55
>XP_005246794
          Length = 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SKSSNANW 8
          S SSN+ W
Sbjct: 49 SSSSNSGW 56
>XP_006712734
          Length = 424

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SKSSNANW 8
          S SSN+ W
Sbjct: 51 SSSSNSGW 58
>XP_006710204
          Length = 119

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SKSSNANW 8
          S +SNA W
Sbjct: 16 SSNSNARW 23
>NP_001032401
          Length = 736

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SKSSNAN 7
           SKSSN+N
Sbjct: 212 SKSSNSN 218
>NP_055508
          Length = 883

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SKSSNAN 7
           SKSSN+N
Sbjct: 359 SKSSNSN 365
>NP_008958
          Length = 1522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 3    SSNANWP 9
            +SN  WP
Sbjct: 1158 ASNLQWP 1164
>NP_005392
          Length = 1187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1  SKSSNANW 8
          SKS  A W
Sbjct: 68 SKSQQARW 75
>NP_149973
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SKSSNAN 7
           SKSSN N
Sbjct: 155 SKSSNLN 161
>NP_001070817
          Length = 466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SKSSNAN 7
           SKSSN N
Sbjct: 123 SKSSNLN 129
>NP_071918
          Length = 1883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 5/6 (83%)

Query: 3   SSNANW 8
           +SN NW
Sbjct: 220 NSNGNW 225
>NP_064601
          Length = 650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/5 (80%), Positives = 5/5 (100%)

Query: 4   SNANW 8
           +NANW
Sbjct: 337 TNANW 341
>NP_775922
          Length = 6996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   KSSNANW 8
           K +NA+W
Sbjct: 539 KETNADW 545
>XP_005260203
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  SKSSNAN 7
          SKSSN N
Sbjct: 79 SKSSNLN 85
>XP_005254649
          Length = 1819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 5/6 (83%)

Query: 3   SSNANW 8
           +SN NW
Sbjct: 243 NSNGNW 248
>XP_005254648
          Length = 1906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 5/6 (83%)

Query: 3   SSNANW 8
           +SN NW
Sbjct: 243 NSNGNW 248
>XP_005247133
          Length = 1517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 3    SSNANWP 9
            +SN  WP
Sbjct: 1153 ASNLQWP 1159
>XP_005245478
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/5 (80%), Positives = 5/5 (100%)

Query: 4  SNANW 8
          +NANW
Sbjct: 47 TNANW 51
>XP_005245477
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/5 (80%), Positives = 5/5 (100%)

Query: 4  SNANW 8
          +NANW
Sbjct: 47 TNANW 51
>XP_005245476
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/5 (80%), Positives = 5/5 (100%)

Query: 4   SNANW 8
           +NANW
Sbjct: 133 TNANW 137
>XP_005245475
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/5 (80%), Positives = 5/5 (100%)

Query: 4   SNANW 8
           +NANW
Sbjct: 206 TNANW 210
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.291    0.104    0.339 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 510,290
Number of extensions: 544
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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