Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     665
NP_001035957                                                           19     665
XP_006721991                                                           19     665
XP_006721990                                                           19     665
XP_006721989                                                           19     665
XP_005258041                                                           19     665
XP_006721988                                                           19     665
XP_006721987                                                           19     665
XP_006721986                                                           19     665
XP_005258040                                                           19     665
XP_006721985                                                           19     665
NP_002067                                                              17    4312
NP_006286                                                              16    5631
XP_005275347                                                           16    5631
XP_005275078                                                           16    5631
XP_005272926                                                           16    5631
XP_005274943                                                           16    5631
XP_005249419                                                           16    5631
NP_036478                                                              16    7355
NP_057637                                                              16    7355
NP_714941                                                              16    7355
NP_714940                                                              16    7355
NP_001180286                                                           16    7355
NP_001034636                                                           16    7355
NP_055785                                                              16    7355
NP_067013                                                              16    7355
NP_060487                                                              16    7355
NP_001191446                                                           16    7355
NP_001191445                                                           16    7355
XP_005269994                                                           16    7355
XP_006713626                                                           16    7355
XP_005245027                                                           16    7355
XP_005271143                                                           16    7355
XP_005271142                                                           16    7355
XP_005271141                                                           16    7355
NP_065099                                                              15    9605
NP_001191433                                                           15    9605
NP_821077                                                              15    9605
NP_001191435                                                           15    9605
NP_001191434                                                           15    9605
NP_690874                                                              15    9605
NP_001026883                                                           15    9605
NP_001186681                                                           15    9605
NP_001129524                                                           15    9605
NP_689572                                                              15    9605
NP_001186682                                                           15    9605
NP_114159                                                              15    9605
NP_072045                                                              15    9605
XP_005276368                                                           15    9605
XP_006725233                                                           15    9605
XP_006725232                                                           15    9605
XP_006725231                                                           15    9605
XP_006723073                                                           15    9605
XP_006723072                                                           15    9605
XP_005258564                                                           15    9605
XP_005258563                                                           15    9605
XP_005258562                                                           15    9605
XP_006720285                                                           15    9605
XP_005267988                                                           15    9605
XP_005267987                                                           15    9605
XP_005266328                                                           15    9605
XP_005250138                                                           15    9605
XP_006714396                                                           15    9605
XP_006714395                                                           15    9605
XP_006714394                                                           15    9605
XP_005263325                                                           15    9605
XP_005263324                                                           15    9605
XP_005276070                                                           15    9605
NP_478144                                                              15    9605
>NP_000258
          Length = 2818

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKLLNANVD 9
            S LLNANVD
Sbjct: 1150 SNLLNANVD 1158
>NP_001035957
          Length = 2839

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKLLNANVD 9
            S LLNANVD
Sbjct: 1150 SNLLNANVD 1158
>XP_006721991
          Length = 1632

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKLLNANVD 9
            S LLNANVD
Sbjct: 1160 SNLLNANVD 1168
>XP_006721990
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKLLNANVD 9
            S LLNANVD
Sbjct: 1160 SNLLNANVD 1168
>XP_006721989
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKLLNANVD 9
            S LLNANVD
Sbjct: 1160 SNLLNANVD 1168
>XP_005258041
          Length = 2836

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKLLNANVD 9
            S LLNANVD
Sbjct: 1150 SNLLNANVD 1158
>XP_006721988
          Length = 2846

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKLLNANVD 9
            S LLNANVD
Sbjct: 1160 SNLLNANVD 1168
>XP_006721987
          Length = 2849

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKLLNANVD 9
            S LLNANVD
Sbjct: 1160 SNLLNANVD 1168
>XP_006721986
          Length = 2854

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKLLNANVD 9
            S LLNANVD
Sbjct: 1147 SNLLNANVD 1155
>XP_005258040
          Length = 2857

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKLLNANVD 9
            S LLNANVD
Sbjct: 1150 SNLLNANVD 1158
>XP_006721985
          Length = 2867

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKLLNANVD 9
            S LLNANVD
Sbjct: 1160 SNLLNANVD 1168
>NP_002067
          Length = 552

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           SK+L AN+D
Sbjct: 365 SKMLVANID 373
>NP_006286
          Length = 1264

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SKLLNANVD 9
           ++LLN+N+D
Sbjct: 887 NQLLNSNLD 895
>XP_005275347
          Length = 1265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SKLLNANVD 9
           ++LLN+N+D
Sbjct: 888 NQLLNSNLD 896
>XP_005275078
          Length = 1265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SKLLNANVD 9
           ++LLN+N+D
Sbjct: 888 NQLLNSNLD 896
>XP_005272926
          Length = 1265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SKLLNANVD 9
           ++LLN+N+D
Sbjct: 888 NQLLNSNLD 896
>XP_005274943
          Length = 1265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SKLLNANVD 9
           ++LLN+N+D
Sbjct: 888 NQLLNSNLD 896
>XP_005249419
          Length = 1265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SKLLNANVD 9
           ++LLN+N+D
Sbjct: 888 NQLLNSNLD 896
>NP_036478
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KLLNANVD 9
           K+LNA++D
Sbjct: 476 KILNAHMD 483
>NP_057637
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KLLNANVD 9
           K+LNA++D
Sbjct: 476 KILNAHMD 483
>NP_714941
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KLLNANVD 9
           K+LNA++D
Sbjct: 476 KILNAHMD 483
>NP_714940
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KLLNANVD 9
           K+LNA++D
Sbjct: 476 KILNAHMD 483
>NP_001180286
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KLLNANVD 9
           K+LNA++D
Sbjct: 476 KILNAHMD 483
>NP_001034636
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKLLNANVD 9
           S L+N N+D
Sbjct: 452 SDLINENID 460
>NP_055785
          Length = 792

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  KLLNANVD 9
          K LNAN D
Sbjct: 59 KSLNANTD 66
>NP_067013
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SKLLNANV 8
           SKL+N NV
Sbjct: 255 SKLVNLNV 262
>NP_060487
          Length = 898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SKLLNANVD 9
          SKLL+ N D
Sbjct: 42 SKLLSLNTD 50
>NP_001191446
          Length = 752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  KLLNANVD 9
          K LNAN D
Sbjct: 19 KSLNANTD 26
>NP_001191445
          Length = 748

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  KLLNANVD 9
          K LNAN D
Sbjct: 15 KSLNANTD 22
>XP_005269994
          Length = 898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SKLLNANVD 9
          SKLL+ N D
Sbjct: 42 SKLLSLNTD 50
>XP_006713626
          Length = 295

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKLLNANVD 9
           S L+N N+D
Sbjct: 218 SDLINENID 226
>XP_005245027
          Length = 794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  KLLNANVD 9
          K LNAN D
Sbjct: 59 KSLNANTD 66
>XP_005271143
          Length = 532

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SKLLNANV 8
           SKL+N NV
Sbjct: 255 SKLVNLNV 262
>XP_005271142
          Length = 536

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SKLLNANV 8
           SKL+N NV
Sbjct: 255 SKLVNLNV 262
>XP_005271141
          Length = 537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SKLLNANV 8
           SKL+N NV
Sbjct: 255 SKLVNLNV 262
>NP_065099
          Length = 1286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KLLNANVD 9
           KLLN N D
Sbjct: 372 KLLNDNYD 379
>NP_001191433
          Length = 1164

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           +K+L AN+D
Sbjct: 739 NKMLLANID 747
>NP_821077
          Length = 1220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           +K+L AN+D
Sbjct: 739 NKMLLANID 747
>NP_001191435
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           +K+L AN+D
Sbjct: 603 NKMLLANID 611
>NP_001191434
          Length = 1100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           +K+L AN+D
Sbjct: 603 NKMLLANID 611
>NP_690874
          Length = 1164

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           +K+L AN+D
Sbjct: 739 NKMLLANID 747
>NP_001026883
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLLNANVD 9
           K+L AN+D
Sbjct: 194 KILEANMD 201
>NP_001186681
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           +K+L+ NVD
Sbjct: 534 AKILSENVD 542
>NP_001129524
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           +K+L+ NVD
Sbjct: 523 AKILSENVD 531
>NP_689572
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           +K+L+ NVD
Sbjct: 534 AKILSENVD 542
>NP_001186682
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           +K+L+ NVD
Sbjct: 534 AKILSENVD 542
>NP_114159
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLLNANVD 9
           KL+N+N D
Sbjct: 185 KLINSNSD 192
>NP_072045
          Length = 152

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  KLLNANVD 9
          ++LN N+D
Sbjct: 14 RVLNTNID 21
>XP_005276368
          Length = 103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SKLLNANVD 9
          SKL+NA  D
Sbjct: 41 SKLMNAYCD 49
>XP_006725233
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SKLLNANV 8
           SKLLN+ V
Sbjct: 317 SKLLNSGV 324
>XP_006725232
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SKLLNANV 8
           SKLLN+ V
Sbjct: 317 SKLLNSGV 324
>XP_006725231
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SKLLNANV 8
           SKLLN+ V
Sbjct: 317 SKLLNSGV 324
>XP_006723073
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           +K+L+ NVD
Sbjct: 534 AKILSENVD 542
>XP_006723072
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           +K+L+ NVD
Sbjct: 405 AKILSENVD 413
>XP_005258564
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           +K+L+ NVD
Sbjct: 534 AKILSENVD 542
>XP_005258563
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           +K+L+ NVD
Sbjct: 534 AKILSENVD 542
>XP_005258562
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           +K+L+ NVD
Sbjct: 534 AKILSENVD 542
>XP_006720285
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SKLLNANV 8
           SKLLN+ V
Sbjct: 317 SKLLNSGV 324
>XP_005267988
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SKLLNANV 8
           SKLLN+ V
Sbjct: 317 SKLLNSGV 324
>XP_005267987
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SKLLNANV 8
           SKLLN+ V
Sbjct: 317 SKLLNSGV 324
>XP_005266328
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLLNANVD 9
           +K+L AN+D
Sbjct: 494 NKMLLANID 502
>XP_005250138
          Length = 103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SKLLNANVD 9
          SKL+NA  D
Sbjct: 41 SKLMNAYCD 49
>XP_006714396
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLLNANVD 9
           KL+N+N D
Sbjct: 185 KLINSNSD 192
>XP_006714395
          Length = 903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLLNANVD 9
           KL+N+N D
Sbjct: 248 KLINSNSD 255
>XP_006714394
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLLNANVD 9
           KL+N+N D
Sbjct: 349 KLINSNSD 356
>XP_005263325
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLLNANVD 9
           KL+N+N D
Sbjct: 349 KLINSNSD 356
>XP_005263324
          Length = 1004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLLNANVD 9
           KL+N+N D
Sbjct: 349 KLINSNSD 356
>XP_005276070
          Length = 103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SKLLNANVD 9
          SKL+NA  D
Sbjct: 41 SKLMNAYCD 49
>NP_478144
          Length = 873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SKLLNANV 8
           SKLLN+ V
Sbjct: 424 SKLLNSGV 431
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.122    0.301 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 375,211
Number of extensions: 595
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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