Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055244                                                              18    1935
XP_005247419                                                           18    1935
NP_733751                                                              17    3301
NP_055335                                                              17    3301
NP_001099008                                                           17    3301
XP_006721482                                                           17    3301
XP_005256470                                                           17    3301
XP_006716142                                                           17    3301
XP_005250088                                                           17    3301
XP_006716141                                                           17    3301
XP_005250085                                                           17    3301
XP_006716140                                                           17    3301
XP_005250084                                                           17    3301
XP_005250083                                                           17    3301
XP_005250082                                                           17    3301
NP_004589                                                              16    5631
NP_000039                                                              16    7355
NP_001020117                                                           16    7355
NP_001020114                                                           16    7355
NP_001020115                                                           16    7355
NP_057129                                                              16    7355
XP_006720035                                                           16    7355
XP_005268376                                                           16    7355
XP_006720034                                                           16    7355
XP_006720033                                                           16    7355
XP_005268375                                                           16    7355
XP_006720032                                                           16    7355
NP_060375                                                              16    7355
NP_001191763                                                           15    9605
NP_001191760                                                           15    9605
NP_060545                                                              15    9605
NP_001153844                                                           15    9605
NP_113654                                                              15    9605
NP_001274152                                                           15    9605
NP_066000                                                              15    9605
NP_892006                                                              15    9605
NP_149062                                                              15    9605
NP_059990                                                              15    9605
NP_001073339                                                           15    9605
NP_001073340                                                           15    9605
NP_817084                                                              15    9605
NP_006763                                                              15    9605
NP_054858                                                              15    9605
XP_006716727                                                           15    9605
XP_005251134                                                           15    9605
XP_006715488                                                           15    9605
XP_006715487                                                           15    9605
XP_006715486                                                           15    9605
XP_006715485                                                           15    9605
XP_006715484                                                           15    9605
XP_006715483                                                           15    9605
XP_006715482                                                           15    9605
XP_006715481                                                           15    9605
XP_006715480                                                           15    9605
XP_006715479                                                           15    9605
XP_006715478                                                           15    9605
XP_006715477                                                           15    9605
XP_006715476                                                           15    9605
XP_006715475                                                           15    9605
XP_006715474                                                           15    9605
XP_006715473                                                           15    9605
XP_006715472                                                           15    9605
XP_006715471                                                           15    9605
XP_006715470                                                           15    9605
XP_006713781                                                           15    9605
XP_005265322                                                           15    9605
NP_116193                                                              15    9605
>NP_055244
          Length = 984

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   KLKSLIGA 9
           KLKSL+GA
Sbjct: 388 KLKSLLGA 395
>XP_005247419
          Length = 1014

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   KLKSLIGA 9
           KLKSL+GA
Sbjct: 388 KLKSLLGA 395
>NP_733751
          Length = 4911

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           SKLKS IGA
Sbjct: 910 SKLKSGIGA 918
>NP_055335
          Length = 1328

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           SKLK L+G+
Sbjct: 227 SKLKKLVGS 235
>NP_001099008
          Length = 1332

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           SKLK L+G+
Sbjct: 227 SKLKKLVGS 235
>XP_006721482
          Length = 723

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           SKLK L+G+
Sbjct: 227 SKLKKLVGS 235
>XP_005256470
          Length = 1120

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           SKLK L+G+
Sbjct: 227 SKLKKLVGS 235
>XP_006716142
          Length = 4927

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           SKLKS IGA
Sbjct: 911 SKLKSGIGA 919
>XP_005250088
          Length = 4928

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           SKLKS IGA
Sbjct: 911 SKLKSGIGA 919
>XP_006716141
          Length = 4959

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           SKLKS IGA
Sbjct: 911 SKLKSGIGA 919
>XP_005250085
          Length = 4979

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           SKLKS IGA
Sbjct: 911 SKLKSGIGA 919
>XP_006716140
          Length = 4982

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           SKLKS IGA
Sbjct: 911 SKLKSGIGA 919
>XP_005250084
          Length = 4982

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           SKLKS IGA
Sbjct: 911 SKLKSGIGA 919
>XP_005250083
          Length = 4982

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           SKLKS IGA
Sbjct: 910 SKLKSGIGA 918
>XP_005250082
          Length = 4983

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           SKLKS IGA
Sbjct: 911 SKLKSGIGA 919
>NP_004589
          Length = 439

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           SK KSL+GA
Sbjct: 324 SKGKSLLGA 332
>NP_000039
          Length = 464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLKSLIGA 9
           +LK LIGA
Sbjct: 95  RLKELIGA 102
>NP_001020117
          Length = 438

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLKSLIGA 9
           +LK LIGA
Sbjct: 95  RLKELIGA 102
>NP_001020114
          Length = 464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLKSLIGA 9
           +LK LIGA
Sbjct: 95  RLKELIGA 102
>NP_001020115
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLKSLIGA 9
           +LK LIGA
Sbjct: 95  RLKELIGA 102
>NP_057129
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  SKLKSLIGA 9
          S +KSLIGA
Sbjct: 63 SIVKSLIGA 71
>XP_006720035
          Length = 411

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SKLKSLIGA 9
          +KLK+ IGA
Sbjct: 69 NKLKTAIGA 77
>XP_005268376
          Length = 543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SKLKSLIGA 9
          +KLK+ IGA
Sbjct: 69 NKLKTAIGA 77
>XP_006720034
          Length = 613

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SKLKSLIGA 9
          +KLK+ IGA
Sbjct: 69 NKLKTAIGA 77
>XP_006720033
          Length = 646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SKLKSLIGA 9
          +KLK+ IGA
Sbjct: 69 NKLKTAIGA 77
>XP_005268375
          Length = 655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SKLKSLIGA 9
          +KLK+ IGA
Sbjct: 69 NKLKTAIGA 77
>XP_006720032
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SKLKSLIGA 9
          +KLK+ IGA
Sbjct: 69 NKLKTAIGA 77
>NP_060375
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SKLKSLIGA 9
          +KLK+ IGA
Sbjct: 69 NKLKTAIGA 77
>NP_001191763
          Length = 470

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SKLKSLIGA 9
          SK++ L+GA
Sbjct: 75 SKIRMLLGA 83
>NP_001191760
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SKLKSLIGA 9
          SK++ L+GA
Sbjct: 75 SKIRMLLGA 83
>NP_060545
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SKLKSLIGA 9
          SK++ L+GA
Sbjct: 75 SKIRMLLGA 83
>NP_001153844
          Length = 1148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KLKSLIG 8
           K+KSL+G
Sbjct: 556 KMKSLLG 562
>NP_113654
          Length = 1246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KLKSLIG 8
           K+KSL+G
Sbjct: 654 KMKSLLG 660
>NP_001274152
          Length = 1791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           S+LK ++GA
Sbjct: 237 SRLKVIVGA 245
>NP_066000
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KLKSLIG 8
           KLK LIG
Sbjct: 532 KLKKLIG 538
>NP_892006
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1495 SKLSSIVG 1502
>NP_149062
          Length = 8749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>NP_059990
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           +K+K LIGA
Sbjct: 846 AKVKLLIGA 854
>NP_001073339
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SKLKSLIGA 9
           SKL++L+G+
Sbjct: 234 SKLEALLGS 242
>NP_001073340
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SKLKSLIGA 9
           SKL++L+G+
Sbjct: 226 SKLEALLGS 234
>NP_817084
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SKLKSLIGA 9
           SKL++L+G+
Sbjct: 226 SKLEALLGS 234
>NP_006763
          Length = 1343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SKLKSLIG 8
            S++KS+IG
Sbjct: 1257 SQIKSIIG 1264
>NP_054858
          Length = 1791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKLKSLIGA 9
           S+LK ++GA
Sbjct: 237 SRLKVIVGA 245
>XP_006716727
          Length = 1139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KLKSLIG 8
           K+KSL+G
Sbjct: 547 KMKSLLG 553
>XP_005251134
          Length = 1148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KLKSLIG 8
           K+KSL+G
Sbjct: 556 KMKSLLG 562
>XP_006715488
          Length = 8721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715487
          Length = 8744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715486
          Length = 8758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715485
          Length = 8793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1449 SKLSSIVG 1456
>XP_006715484
          Length = 8794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715483
          Length = 8795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715482
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1495 SKLSSIVG 1502
>XP_006715481
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1455 SKLSSIVG 1462
>XP_006715480
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715479
          Length = 8804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715478
          Length = 8809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715477
          Length = 8822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1478 SKLSSIVG 1485
>XP_006715476
          Length = 8823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715475
          Length = 8827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715474
          Length = 8829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1485 SKLSSIVG 1492
>XP_006715473
          Length = 8832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715472
          Length = 8839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1495 SKLSSIVG 1502
>XP_006715471
          Length = 8842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006715470
          Length = 8846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SKLKSLIG 8
            SKL S++G
Sbjct: 1502 SKLSSIVG 1509
>XP_006713781
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KLKSLIG 8
           KLK LIG
Sbjct: 532 KLKKLIG 538
>XP_005265322
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SKLKSLIGA 9
          SK++ L+GA
Sbjct: 75 SKIRMLLGA 83
>NP_116193
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  SKLKSLI 7
          SKLKSL+
Sbjct: 52 SKLKSLL 58
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.127    0.299 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 329,556
Number of extensions: 540
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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