Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           19     869
NP_004561                                                              19     869
NP_001275703                                                           19     869
XP_005253450                                                           19     869
XP_006719151                                                           19     869
NP_004628                                                              17    4312
NP_997191                                                              17    4312
NP_001152956                                                           17    4312
NP_775105                                                              17    4312
NP_001036148                                                           17    4312
XP_006715506                                                           17    4312
XP_006715505                                                           17    4312
XP_006715504                                                           17    4312
XP_006715503                                                           17    4312
XP_006715502                                                           17    4312
XP_006711682                                                           17    4312
NP_065975                                                              16    5631
NP_060250                                                              16    7355
NP_001032                                                              16    7355
NP_644814                                                              16    7355
NP_001182005                                                           16    7355
XP_006723251                                                           16    7355
XP_006721859                                                           16    7355
XP_005251324                                                           16    7355
XP_005251323                                                           16    7355
NP_055833                                                              15    9605
NP_001186871                                                           15    9605
NP_001188358                                                           15    9605
NP_036427                                                              15    9605
NP_001186210                                                           15    9605
NP_001035374                                                           15    9605
NP_001035375                                                           15    9605
NP_065856                                                              15    9605
XP_006724247                                                           15    9605
XP_006724246                                                           15    9605
XP_006724245                                                           15    9605
XP_006724244                                                           15    9605
XP_006724243                                                           15    9605
XP_005261477                                                           15    9605
XP_005261476                                                           15    9605
XP_005261474                                                           15    9605
XP_006724242                                                           15    9605
XP_005261473                                                           15    9605
XP_005261472                                                           15    9605
XP_006722575                                                           15    9605
XP_006721308                                                           15    9605
XP_005256149                                                           15    9605
XP_006715464                                                           15    9605
XP_006715463                                                           15    9605
XP_006715462                                                           15    9605
XP_006715461                                                           15    9605
XP_006715460                                                           15    9605
XP_006715459                                                           15    9605
XP_006715458                                                           15    9605
XP_006715457                                                           15    9605
XP_006715456                                                           15    9605
>NP_001275701
          Length = 1486

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKKSSNQYL 9
            SKKSSN YL
Sbjct: 1255 SKKSSNLYL 1263
>NP_004561
          Length = 1445

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKKSSNQYL 9
            SKKSSN YL
Sbjct: 1214 SKKSSNLYL 1222
>NP_001275703
          Length = 1264

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKKSSNQYL 9
            SKKSSN YL
Sbjct: 1033 SKKSSNLYL 1041
>XP_005253450
          Length = 1486

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKKSSNQYL 9
            SKKSSN YL
Sbjct: 1255 SKKSSNLYL 1263
>XP_006719151
          Length = 1486

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SKKSSNQYL 9
            SKKSSN YL
Sbjct: 1255 SKKSSNLYL 1263
>NP_004628
          Length = 207

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SKKSSNQY 8
          +KK SNQY
Sbjct: 30 NKKFSNQY 37
>NP_997191
          Length = 1888

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SK+  NQY+
Sbjct: 710 SKRKQNQYI 718
>NP_001152956
          Length = 1736

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SK+  NQY+
Sbjct: 710 SKRKQNQYI 718
>NP_775105
          Length = 1659

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SKKSSNQYL 9
           S +SSNQ+L
Sbjct: 142 SSESSNQFL 150
>NP_001036148
          Length = 1683

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SKKSSNQYL 9
           S +SSNQ+L
Sbjct: 142 SSESSNQFL 150
>XP_006715506
          Length = 1507

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SKKSSNQYL 9
           S +SSNQ+L
Sbjct: 142 SSESSNQFL 150
>XP_006715505
          Length = 1673

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SKKSSNQYL 9
           S +SSNQ+L
Sbjct: 142 SSESSNQFL 150
>XP_006715504
          Length = 1683

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SKKSSNQYL 9
           S +SSNQ+L
Sbjct: 142 SSESSNQFL 150
>XP_006715503
          Length = 1707

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SKKSSNQYL 9
           S +SSNQ+L
Sbjct: 142 SSESSNQFL 150
>XP_006715502
          Length = 1707

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SKKSSNQYL 9
           S +SSNQ+L
Sbjct: 142 SSESSNQFL 150
>XP_006711682
          Length = 1739

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SK+  NQY+
Sbjct: 561 SKRKQNQYI 569
>NP_065975
          Length = 441

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SKK  NQ++
Sbjct: 196 SKKDQNQFI 204
>NP_060250
          Length = 2997

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SKKSSNQ 7
           SKKSSN+
Sbjct: 695 SKKSSNK 701
>NP_001032
          Length = 1827

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KSSNQYL 9
           KSS QYL
Sbjct: 683 KSSRQYL 689
>NP_644814
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  KSSNQYL 9
          KSS QYL
Sbjct: 25 KSSEQYL 31
>NP_001182005
          Length = 198

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  KSSNQYL 9
          KSS QYL
Sbjct: 45 KSSKQYL 51
>XP_006723251
          Length = 198

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  KSSNQYL 9
          KSS QYL
Sbjct: 45 KSSKQYL 51
>XP_006721859
          Length = 844

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  KSSNQYL 9
          KSS QYL
Sbjct: 25 KSSEQYL 31
>XP_005251324
          Length = 2996

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SKKSSNQ 7
           SKKSSN+
Sbjct: 695 SKKSSNK 701
>XP_005251323
          Length = 2997

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SKKSSNQ 7
           SKKSSN+
Sbjct: 695 SKKSSNK 701
>NP_055833
          Length = 2465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KKSSNQYL 9
            KKSSN+ L
Sbjct: 1311 KKSSNEKL 1318
>NP_001186871
          Length = 2476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KKSSNQYL 9
            KKSSN+ L
Sbjct: 1302 KKSSNEKL 1309
>NP_001188358
          Length = 2170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SKKS  +YL
Sbjct: 905 SKKSKARYL 913
>NP_036427
          Length = 2220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SKKS  +YL
Sbjct: 955 SKKSKARYL 963
>NP_001186210
          Length = 2220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SKKS  +YL
Sbjct: 955 SKKSKARYL 963
>NP_001035374
          Length = 698

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KSSNQY 8
           KS+NQY
Sbjct: 674 KSNNQY 679
>NP_001035375
          Length = 651

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KSSNQY 8
           KS+NQY
Sbjct: 627 KSNNQY 632
>NP_065856
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKKSSNQYL 9
           +KK +N+YL
Sbjct: 201 TKKLANKYL 209
>XP_006724247
          Length = 1189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SKKS  +YL
Sbjct: 955 SKKSKARYL 963
>XP_006724246
          Length = 2103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SKKS  +YL
Sbjct: 955 SKKSKARYL 963
>XP_006724245
          Length = 2191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SKKS  +YL
Sbjct: 955 SKKSKARYL 963
>XP_006724244
          Length = 2191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SKKS  +YL
Sbjct: 955 SKKSKARYL 963
>XP_006724243
          Length = 2196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SKKS  +YL
Sbjct: 955 SKKSKARYL 963
>XP_005261477
          Length = 2200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SKKS  +YL
Sbjct: 955 SKKSKARYL 963
>XP_005261476
          Length = 2210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SKKS  +YL
Sbjct: 910 SKKSKARYL 918
>XP_005261474
          Length = 2225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SKKS  +YL
Sbjct: 955 SKKSKARYL 963
>XP_006724242
          Length = 2226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SKKS  +YL
Sbjct: 955 SKKSKARYL 963
>XP_005261473
          Length = 2250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SKKS  +YL
Sbjct: 955 SKKSKARYL 963
>XP_005261472
          Length = 2255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKKSSNQYL 9
           SKKS  +YL
Sbjct: 955 SKKSKARYL 963
>XP_006722575
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKKSSNQYL 9
           +KK +N+YL
Sbjct: 245 TKKLANKYL 253
>XP_006721308
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KSSNQY 8
           KS+NQY
Sbjct: 642 KSNNQY 647
>XP_005256149
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KSSNQY 8
           KS+NQY
Sbjct: 689 KSNNQY 694
>XP_006715464
          Length = 2027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KKSSNQYL 9
            KKSSN+ L
Sbjct: 1311 KKSSNEKL 1318
>XP_006715463
          Length = 2434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KKSSNQYL 9
            KKSSN+ L
Sbjct: 1311 KKSSNEKL 1318
>XP_006715462
          Length = 2452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KKSSNQYL 9
            KKSSN+ L
Sbjct: 1278 KKSSNEKL 1285
>XP_006715461
          Length = 2456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KKSSNQYL 9
            KKSSN+ L
Sbjct: 1302 KKSSNEKL 1309
>XP_006715460
          Length = 2465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KKSSNQYL 9
            KKSSN+ L
Sbjct: 1311 KKSSNEKL 1318
>XP_006715459
          Length = 2475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KKSSNQYL 9
            KKSSN+ L
Sbjct: 1301 KKSSNEKL 1308
>XP_006715458
          Length = 2476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KKSSNQYL 9
            KKSSN+ L
Sbjct: 1302 KKSSNEKL 1309
>XP_006715457
          Length = 2485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KKSSNQYL 9
            KKSSN+ L
Sbjct: 1311 KKSSNEKL 1318
>XP_006715456
          Length = 2485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KKSSNQYL 9
            KKSSN+ L
Sbjct: 1311 KKSSNEKL 1318
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.287    0.102    0.238 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 444,965
Number of extensions: 854
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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