Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005219                                                              20     509
NP_001276866                                                           20     509
NP_004439                                                              20     509
NP_001276865                                                           20     509
NP_001005862                                                           20     509
XP_005257197                                                           20     509
XP_006721828                                                           20     509
NP_001171313                                                           17    2528
NP_003130                                                              17    2528
XP_006720036                                                           17    2528
XP_005268376                                                           17    2528
XP_006720034                                                           17    2528
XP_006720033                                                           17    2528
XP_005268375                                                           17    2528
XP_006720032                                                           17    2528
NP_060375                                                              17    2528
NP_004295                                                              17    4312
NP_001008225                                                           17    4312
NP_060473                                                              17    4312
NP_071942                                                              17    4312
NP_055045                                                              17    4312
NP_065998                                                              17    4312
NP_001247431                                                           17    4312
XP_005256132                                                           17    4312
XP_006721303                                                           17    4312
XP_005256131                                                           17    4312
XP_005254586                                                           17    4312
XP_005254585                                                           17    4312
XP_005254584                                                           17    4312
NP_037509                                                              16    5631
NP_115901                                                              16    5631
NP_068746                                                              16    5631
NP_065937                                                              16    5631
NP_001158067                                                           16    5631
XP_005271696                                                           16    5631
XP_005271695                                                           16    5631
XP_005271694                                                           16    5631
XP_005271693                                                           16    5631
XP_005271690                                                           16    5631
XP_005271689                                                           16    5631
XP_005271688                                                           16    5631
XP_005271687                                                           16    5631
NP_001155056                                                           16    7355
NP_060216                                                              16    7355
XP_006711403                                                           16    7355
NP_653300                                                              16    7355
NP_001032360                                                           16    7355
NP_003742                                                              16    7355
NP_899645                                                              15    9605
NP_899647                                                              15    9605
NP_899648                                                              15    9605
NP_004281                                                              15    9605
NP_001188294                                                           15    9605
NP_899646                                                              15    9605
NP_000867                                                              15    9605
NP_002894                                                              15    9605
XP_005268600                                                           15    9605
XP_005268599                                                           15    9605
XP_005268598                                                           15    9605
XP_005268597                                                           15    9605
XP_005268596                                                           15    9605
XP_005268595                                                           15    9605
XP_005268594                                                           15    9605
XP_005268593                                                           15    9605
>NP_005219
          Length = 1210

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KANKEILD 9
           KANKEILD
Sbjct: 754 KANKEILD 761
>NP_001276866
          Length = 1055

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KANKEILD 9
           KANKEILD
Sbjct: 762 KANKEILD 769
>NP_004439
          Length = 1255

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KANKEILD 9
           KANKEILD
Sbjct: 762 KANKEILD 769
>NP_001276865
          Length = 1240

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KANKEILD 9
           KANKEILD
Sbjct: 747 KANKEILD 754
>NP_001005862
          Length = 1225

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KANKEILD 9
           KANKEILD
Sbjct: 732 KANKEILD 739
>XP_005257197
          Length = 1225

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KANKEILD 9
           KANKEILD
Sbjct: 732 KANKEILD 739
>XP_006721828
          Length = 1336

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KANKEILD 9
           KANKEILD
Sbjct: 843 KANKEILD 850
>NP_001171313
          Length = 610

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ANKEILD 9
           ANKE+LD
Sbjct: 226 ANKEVLD 232
>NP_003130
          Length = 638

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ANKEILD 9
           ANKE+LD
Sbjct: 254 ANKEVLD 260
>XP_006720036
          Length = 296

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SKANKEIL 8
           SK NKEIL
Sbjct: 112 SKGNKEIL 119
>XP_005268376
          Length = 543

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SKANKEIL 8
           SK NKEIL
Sbjct: 493 SKGNKEIL 500
>XP_006720034
          Length = 613

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SKANKEIL 8
           SK NKEIL
Sbjct: 429 SKGNKEIL 436
>XP_006720033
          Length = 646

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SKANKEIL 8
           SK NKEIL
Sbjct: 462 SKGNKEIL 469
>XP_005268375
          Length = 655

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SKANKEIL 8
           SK NKEIL
Sbjct: 493 SKGNKEIL 500
>XP_006720032
          Length = 677

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SKANKEIL 8
           SK NKEIL
Sbjct: 493 SKGNKEIL 500
>NP_060375
          Length = 677

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SKANKEIL 8
           SK NKEIL
Sbjct: 493 SKGNKEIL 500
>NP_004295
          Length = 1620

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    SKANKEILD 9
            SK+N+E+L+
Sbjct: 1332 SKSNQEVLE 1340
>NP_001008225
          Length = 1403

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKANKEILD 9
           +K N+E+LD
Sbjct: 864 AKTNRELLD 872
>NP_060473
          Length = 1416

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKANKEILD 9
           +K N+E+LD
Sbjct: 877 AKTNRELLD 885
>NP_071942
          Length = 173

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SKANKEILD 9
           +K+NKEI++
Sbjct: 92  TKSNKEIME 100
>NP_055045
          Length = 627

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SKANKEILD 9
          SKANKE  D
Sbjct: 48 SKANKEFGD 56
>NP_065998
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKANKEILD 9
           +K NK ILD
Sbjct: 420 AKGNKSILD 428
>NP_001247431
          Length = 589

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SKANKEILD 9
          SKANKE  D
Sbjct: 48 SKANKEFGD 56
>XP_005256132
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKANKEILD 9
           +K NK ILD
Sbjct: 420 AKGNKSILD 428
>XP_006721303
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKANKEILD 9
           +K NK ILD
Sbjct: 420 AKGNKSILD 428
>XP_005256131
          Length = 494

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SKANKEILD 9
           +K NK ILD
Sbjct: 458 AKGNKSILD 466
>XP_005254586
          Length = 1392

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKANKEILD 9
           +K N+E+LD
Sbjct: 853 AKTNRELLD 861
>XP_005254585
          Length = 1405

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKANKEILD 9
           +K N+E+LD
Sbjct: 866 AKTNRELLD 874
>XP_005254584
          Length = 1411

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKANKEILD 9
           +K N+E+LD
Sbjct: 872 AKTNRELLD 880
>NP_037509
          Length = 778

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           K NK+ILD
Sbjct: 740 KRNKKILD 747
>NP_115901
          Length = 769

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           K NK+ILD
Sbjct: 731 KRNKKILD 738
>NP_068746
          Length = 669

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SKANKEILD 9
           +K NK++LD
Sbjct: 98  TKNNKQVLD 106
>NP_065937
          Length = 1077

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SKANKEIL 8
          S ANKE+L
Sbjct: 81 SAANKEVL 88
>NP_001158067
          Length = 1036

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KANKEILD 9
            K NK+ILD
Sbjct: 998  KRNKKILD 1005
>XP_005271696
          Length = 1045

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SKANKEIL 8
          S ANKE+L
Sbjct: 81 SAANKEVL 88
>XP_005271695
          Length = 1046

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SKANKEIL 8
          S ANKE+L
Sbjct: 81 SAANKEVL 88
>XP_005271694
          Length = 1078

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SKANKEIL 8
          S ANKE+L
Sbjct: 81 SAANKEVL 88
>XP_005271693
          Length = 1080

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SKANKEIL 8
          S ANKE+L
Sbjct: 81 SAANKEVL 88
>XP_005271690
          Length = 1118

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SKANKEIL 8
          S ANKE+L
Sbjct: 59 SAANKEVL 66
>XP_005271689
          Length = 1137

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SKANKEIL 8
          S ANKE+L
Sbjct: 78 SAANKEVL 85
>XP_005271688
          Length = 1139

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SKANKEIL 8
          S ANKE+L
Sbjct: 81 SAANKEVL 88
>XP_005271687
          Length = 1140

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SKANKEIL 8
          S ANKE+L
Sbjct: 81 SAANKEVL 88
>NP_001155056
          Length = 913

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKANKEIL 8
           ++ANKE+L
Sbjct: 585 ARANKELL 592
>NP_060216
          Length = 929

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SKANKEIL 8
           ++ANKE+L
Sbjct: 582 ARANKELL 589
>XP_006711403
          Length = 961

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KANKEIL 8
           KAN+EIL
Sbjct: 374 KANQEIL 380
>NP_653300
          Length = 1029

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KANKEIL 8
           KAN+EIL
Sbjct: 442 KANQEIL 448
>NP_001032360
          Length = 814

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SKANKEILD 9
           SKA+KE+++
Sbjct: 740 SKASKELVE 748
>NP_003742
          Length = 814

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SKANKEILD 9
           SKA+KE+++
Sbjct: 740 SKASKELVE 748
>NP_899645
          Length = 348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           +ANK +LD
Sbjct: 243 EANKRLLD 250
>NP_899647
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           +ANK +LD
Sbjct: 369 EANKRLLD 376
>NP_899648
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           +ANK +LD
Sbjct: 369 EANKRLLD 376
>NP_004281
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           +ANK +LD
Sbjct: 369 EANKRLLD 376
>NP_001188294
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           +ANK +LD
Sbjct: 369 EANKRLLD 376
>NP_899646
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           +ANK +LD
Sbjct: 369 EANKRLLD 376
>NP_000867
          Length = 2491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KANKEI 7
           KANKE+
Sbjct: 167 KANKEV 172
>NP_002894
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ANKEIL 8
           ANKEIL
Sbjct: 178 ANKEIL 183
>XP_005268600
          Length = 298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           +ANK +LD
Sbjct: 193 EANKRLLD 200
>XP_005268599
          Length = 298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           +ANK +LD
Sbjct: 193 EANKRLLD 200
>XP_005268598
          Length = 348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           +ANK +LD
Sbjct: 243 EANKRLLD 250
>XP_005268597
          Length = 348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           +ANK +LD
Sbjct: 243 EANKRLLD 250
>XP_005268596
          Length = 348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           +ANK +LD
Sbjct: 243 EANKRLLD 250
>XP_005268595
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           +ANK +LD
Sbjct: 369 EANKRLLD 376
>XP_005268594
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           +ANK +LD
Sbjct: 369 EANKRLLD 376
>XP_005268593
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KANKEILD 9
           +ANK +LD
Sbjct: 369 EANKRLLD 376
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.296    0.118    0.279 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 463,209
Number of extensions: 931
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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