Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001234926                                                           17    4312
NP_002947                                                              17    4312
NP_937883                                                              17    4312
XP_006719618                                                           17    4312
XP_006719617                                                           17    4312
XP_006719616                                                           17    4312
XP_006719615                                                           17    4312
XP_006719614                                                           17    4312
XP_005253652                                                           17    4312
XP_005253651                                                           17    4312
XP_005253650                                                           17    4312
NP_001497                                                              16    7355
NP_056110                                                              15    9605
XP_005258159                                                           15    9605
XP_006722384                                                           15    9605
>NP_001234926
          Length = 1438

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SISLTSAL 8
            SIS+TSAL
Sbjct: 1234 SISITSAL 1241
>NP_002947
          Length = 1427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SISLTSAL 8
            SIS+TSAL
Sbjct: 1223 SISITSAL 1230
>NP_937883
          Length = 1392

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SISLTSAL 8
            SIS+TSAL
Sbjct: 1188 SISITSAL 1195
>XP_006719618
          Length = 1394

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SISLTSAL 8
            SIS+TSAL
Sbjct: 1188 SISITSAL 1195
>XP_006719617
          Length = 1401

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SISLTSAL 8
            SIS+TSAL
Sbjct: 1195 SISITSAL 1202
>XP_006719616
          Length = 1405

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SISLTSAL 8
            SIS+TSAL
Sbjct: 1199 SISITSAL 1206
>XP_006719615
          Length = 1429

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SISLTSAL 8
            SIS+TSAL
Sbjct: 1223 SISITSAL 1230
>XP_006719614
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SISLTSAL 8
            SIS+TSAL
Sbjct: 1234 SISITSAL 1241
>XP_005253652
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SISLTSAL 8
            SIS+TSAL
Sbjct: 1234 SISITSAL 1241
>XP_005253651
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SISLTSAL 8
            SIS+TSAL
Sbjct: 1234 SISITSAL 1241
>XP_005253650
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    SISLTSAL 8
            SIS+TSAL
Sbjct: 1234 SISITSAL 1241
>NP_001497
          Length = 356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SLTSALA 9
           SLTSALA
Sbjct: 330 SLTSALA 336
>NP_056110
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ISLTSALA 9
            I++TSALA
Sbjct: 1081 INITSALA 1088
>XP_005258159
          Length = 1817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ISLTSALA 9
           I++TSALA
Sbjct: 893 INITSALA 900
>XP_006722384
          Length = 1877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ISLTSALA 9
           I++TSALA
Sbjct: 953 INITSALA 960
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.108    0.225 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 207,480
Number of extensions: 170
Number of successful extensions: 15
Number of sequences better than 10000.0: 15
Number of HSP's gapped: 15
Number of HSP's successfully gapped: 15
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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