Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              19     665
NP_009297                                                              19     665
NP_001161710                                                           19     665
NP_001161709                                                           19     665
NP_001161708                                                           19     665
NP_009298                                                              19     665
NP_001129473                                                           19     665
NP_005149                                                              19     665
NP_001161711                                                           19     665
XP_005245145                                                           19     665
NP_001129472                                                           19     665
NP_113676                                                              18    1935
NP_588608                                                              17    4312
NP_065996                                                              17    4312
NP_060113                                                              17    4312
XP_006722025                                                           17    4312
XP_006722024                                                           17    4312
XP_005257527                                                           17    4312
XP_005257526                                                           17    4312
XP_005257525                                                           17    4312
XP_005257524                                                           17    4312
XP_005270063                                                           17    4312
XP_005270062                                                           17    4312
XP_005270061                                                           17    4312
NP_057413                                                              16    5631
NP_005875                                                              16    5631
NP_001014831                                                           16    5631
NP_001014834                                                           16    5631
NP_001014832                                                           16    5631
NP_001014835                                                           16    5631
XP_006723035                                                           16    5631
XP_006723034                                                           16    5631
XP_006713267                                                           16    5631
XP_005265278                                                           16    5631
XP_006713266                                                           16    5631
NP_055873                                                              16    7355
NP_001009814                                                           16    7355
NP_056481                                                              16    7355
NP_055524                                                              16    7355
NP_937793                                                              16    7355
XP_006723838                                                           16    7355
XP_005260450                                                           16    7355
XP_006723837                                                           16    7355
XP_006723836                                                           16    7355
XP_006723835                                                           16    7355
XP_006719855                                                           16    7355
XP_006719853                                                           16    7355
NP_005111                                                              15    9605
NP_002902                                                              15    9605
NP_001004023                                                           15    9605
NP_001004419                                                           15    9605
NP_037401                                                              15    9605
NP_001184246                                                           15    9605
XP_005262376                                                           15    9605
XP_005262374                                                           15    9605
XP_005260072                                                           15    9605
XP_005248339                                                           15    9605
XP_006711640                                                           15    9605
XP_005273372                                                           15    9605
XP_006711639                                                           15    9605
XP_005273373                                                           15    9605
NP_003573                                                              15    9605
>NP_005148
          Length = 1130

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SI LRYEGR
Sbjct: 162 SISLRYEGR 170
>NP_009297
          Length = 1149

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SI LRYEGR
Sbjct: 181 SISLRYEGR 189
>NP_001161710
          Length = 1058

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SI LRYEGR
Sbjct: 187 SISLRYEGR 195
>NP_001161709
          Length = 1079

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SI LRYEGR
Sbjct: 208 SISLRYEGR 216
>NP_001161708
          Length = 1161

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SI LRYEGR
Sbjct: 187 SISLRYEGR 195
>NP_009298
          Length = 1182

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SI LRYEGR
Sbjct: 208 SISLRYEGR 216
>NP_001129473
          Length = 542

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SI LRYEGR
Sbjct: 187 SISLRYEGR 195
>NP_005149
          Length = 1167

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SI LRYEGR
Sbjct: 193 SISLRYEGR 201
>NP_001161711
          Length = 1043

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SI LRYEGR
Sbjct: 172 SISLRYEGR 180
>XP_005245145
          Length = 1146

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SI LRYEGR
Sbjct: 172 SISLRYEGR 180
>NP_001129472
          Length = 1064

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SI LRYEGR
Sbjct: 193 SISLRYEGR 201
>NP_113676
          Length = 705

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILLRYEG 8
           +LLRYEG
Sbjct: 243 VLLRYEG 249
>NP_588608
          Length = 354

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           +ILL Y+GR
Sbjct: 299 AILLDYQGR 307
>NP_065996
          Length = 3184

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILLRYEG 8
           +LLRY+G
Sbjct: 321 VLLRYDG 327
>NP_060113
          Length = 628

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLRYEG 8
           LLRYEG
Sbjct: 206 LLRYEG 211
>XP_006722025
          Length = 464

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  LLRYEG 8
          LLRYEG
Sbjct: 42 LLRYEG 47
>XP_006722024
          Length = 523

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLRYEG 8
           LLRYEG
Sbjct: 231 LLRYEG 236
>XP_005257527
          Length = 628

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLRYEG 8
           LLRYEG
Sbjct: 206 LLRYEG 211
>XP_005257526
          Length = 630

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLRYEG 8
           LLRYEG
Sbjct: 208 LLRYEG 213
>XP_005257525
          Length = 651

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLRYEG 8
           LLRYEG
Sbjct: 229 LLRYEG 234
>XP_005257524
          Length = 653

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLRYEG 8
           LLRYEG
Sbjct: 231 LLRYEG 236
>XP_005270063
          Length = 2005

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILLRYEG 8
           +LLRY+G
Sbjct: 321 VLLRYDG 327
>XP_005270062
          Length = 3184

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILLRYEG 8
           +LLRY+G
Sbjct: 321 VLLRYDG 327
>XP_005270061
          Length = 3184

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILLRYEG 8
           +LLRY+G
Sbjct: 321 VLLRYDG 327
>NP_057413
          Length = 866

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  ILLRYEG 8
          +LLRY+G
Sbjct: 80 LLLRYDG 86
>NP_005875
          Length = 591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SILL ++GR
Sbjct: 445 SILLTHDGR 453
>NP_001014831
          Length = 591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SILL ++GR
Sbjct: 445 SILLTHDGR 453
>NP_001014834
          Length = 438

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SILL ++GR
Sbjct: 292 SILLTHDGR 300
>NP_001014832
          Length = 591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SILL ++GR
Sbjct: 445 SILLTHDGR 453
>NP_001014835
          Length = 438

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SILL ++GR
Sbjct: 292 SILLTHDGR 300
>XP_006723035
          Length = 438

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SILL ++GR
Sbjct: 292 SILLTHDGR 300
>XP_006723034
          Length = 591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SILL ++GR
Sbjct: 445 SILLTHDGR 453
>XP_006713267
          Length = 866

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  ILLRYEG 8
          +LLRY+G
Sbjct: 80 LLLRYDG 86
>XP_005265278
          Length = 866

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  ILLRYEG 8
          +LLRY+G
Sbjct: 80 LLLRYDG 86
>XP_006713266
          Length = 866

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  ILLRYEG 8
          +LLRY+G
Sbjct: 80 LLLRYDG 86
>NP_055873
          Length = 1905

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SILL +EG+
Sbjct: 344 SILLGHEGK 352
>NP_001009814
          Length = 1039

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SILL +EG+
Sbjct: 344 SILLGHEGK 352
>NP_056481
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SILLRYEG 8
           S+L RY+G
Sbjct: 127 SVLSRYQG 134
>NP_055524
          Length = 3546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SILLRYEG 8
            S+L+ YEG
Sbjct: 3170 SVLVAYEG 3177
>NP_937793
          Length = 536

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SILLRYEGR 9
           + LLR EGR
Sbjct: 150 AFLLRQEGR 158
>XP_006723838
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SILLRYEG 8
           S+L RY+G
Sbjct: 127 SVLSRYQG 134
>XP_005260450
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SILLRYEG 8
           S+L RY+G
Sbjct: 127 SVLSRYQG 134
>XP_006723837
          Length = 422

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SILLRYEG 8
           S+L RY+G
Sbjct: 143 SVLSRYQG 150
>XP_006723836
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SILLRYEG 8
           S+L RY+G
Sbjct: 155 SVLSRYQG 162
>XP_006723835
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SILLRYEG 8
           S+L RY+G
Sbjct: 155 SVLSRYQG 162
>XP_006719855
          Length = 1046

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SILL +EG+
Sbjct: 344 SILLGHEGK 352
>XP_006719853
          Length = 1809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           SILL +EG+
Sbjct: 248 SILLGHEGK 256
>NP_005111
          Length = 2177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   ILLRYEG 8
           +LLRY G
Sbjct: 279 LLLRYSG 285
>NP_002902
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ILLRYE 7
           +LLRYE
Sbjct: 292 VLLRYE 297
>NP_001004023
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           +ILL++ GR
Sbjct: 320 NILLKHHGR 328
>NP_001004419
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SILLRYEG 8
           + LLRY+G
Sbjct: 120 NFLLRYKG 127
>NP_037401
          Length = 191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SILLRYEG 8
           + LLRY+G
Sbjct: 120 NFLLRYKG 127
>NP_001184246
          Length = 154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SILLRYEG 8
          + LLRY+G
Sbjct: 83 NFLLRYKG 90
>XP_005262376
          Length = 2155

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   ILLRYEG 8
           +LLRY G
Sbjct: 279 LLLRYSG 285
>XP_005262374
          Length = 2180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   ILLRYEG 8
           +LLRY G
Sbjct: 279 LLLRYSG 285
>XP_005260072
          Length = 1129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ILLRYE 7
           +LLRYE
Sbjct: 292 VLLRYE 297
>XP_005248339
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SILLRY 6
          SILLRY
Sbjct: 12 SILLRY 17
>XP_006711640
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           +ILL++ GR
Sbjct: 320 NILLKHHGR 328
>XP_005273372
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           +ILL++ GR
Sbjct: 320 NILLKHHGR 328
>XP_006711639
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           +ILL++ GR
Sbjct: 320 NILLKHHGR 328
>XP_005273373
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           +ILL++ GR
Sbjct: 320 NILLKHHGR 328
>NP_003573
          Length = 588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SILLRYEGR 9
           +ILL++ GR
Sbjct: 340 NILLKHHGR 348
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.151    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 524,412
Number of extensions: 1209
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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