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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              17    2528
XP_006714104                                                           17    2528
XP_005265800                                                           17    2528
XP_006714103                                                           17    2528
XP_006714102                                                           17    2528
NP_849157                                                              16    5631
XP_006714159                                                           16    5631
XP_006714158                                                           16    5631
XP_006714157                                                           16    5631
NP_000248                                                              16    7355
NP_001177344                                                           16    7355
NP_647476                                                              16    7355
NP_005632                                                              16    7355
XP_005267754                                                           16    7355
XP_005267753                                                           16    7355
XP_006716165                                                           16    7355
XP_006716164                                                           16    7355
XP_006716163                                                           16    7355
NP_000531                                                              15    9605
NP_001036188                                                           15    9605
NP_940870                                                              15    9605
XP_006723382                                                           15    9605
XP_006723381                                                           15    9605
XP_006723380                                                           15    9605
XP_006715494                                                           15    9605
XP_006715493                                                           15    9605

>NP_006197
          Length = 1089

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SIKLVSTLT 9
           SIKLV TLT
Sbjct: 268 SIKLVYTLT 276



>XP_006714104
          Length = 832

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SIKLVSTLT 9
           SIKLV TLT
Sbjct: 293 SIKLVYTLT 301



>XP_005265800
          Length = 1089

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SIKLVSTLT 9
           SIKLV TLT
Sbjct: 268 SIKLVYTLT 276



>XP_006714103
          Length = 1111

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SIKLVSTLT 9
           SIKLV TLT
Sbjct: 290 SIKLVYTLT 298



>XP_006714102
          Length = 1114

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SIKLVSTLT 9
           SIKLV TLT
Sbjct: 293 SIKLVYTLT 301



>NP_849157
          Length = 1077

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SIKLVSTLT 9
           S+KLVST T
Sbjct: 868 SVKLVSTDT 876



>XP_006714159
          Length = 1077

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SIKLVSTLT 9
           S+KLVST T
Sbjct: 868 SVKLVSTDT 876



>XP_006714158
          Length = 1077

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SIKLVSTLT 9
           S+KLVST T
Sbjct: 868 SVKLVSTDT 876



>XP_006714157
          Length = 1077

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SIKLVSTLT 9
           S+KLVST T
Sbjct: 868 SVKLVSTDT 876



>NP_000248
          Length = 1935

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SIKLVSTL 8
           S+KL+STL
Sbjct: 613 SLKLLSTL 620



>NP_001177344
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IKLVSTLT 9
           +KLVST T
Sbjct: 619 VKLVSTAT 626



>NP_647476
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IKLVSTLT 9
           +KLVST T
Sbjct: 582 VKLVSTAT 589



>NP_005632
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IKLVSTLT 9
           +KLVST T
Sbjct: 582 VKLVSTAT 589



>XP_005267754
          Length = 1087

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SIKLVSTL 8
           S+KL+STL
Sbjct: 613 SLKLLSTL 620



>XP_005267753
          Length = 1935

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SIKLVSTL 8
           S+KL+STL
Sbjct: 613 SLKLLSTL 620



>XP_006716165
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IKLVSTLT 9
           +KLVST T
Sbjct: 572 VKLVSTAT 579



>XP_006716164
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IKLVSTLT 9
           +KLVST T
Sbjct: 572 VKLVSTAT 579



>XP_006716163
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IKLVSTLT 9
           +KLVST T
Sbjct: 582 VKLVSTAT 589



>NP_000531
          Length = 5038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    IKLVSTL 8
            +KLVSTL
Sbjct: 1842 LKLVSTL 1848



>NP_001036188
          Length = 5033

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    IKLVSTL 8
            +KLVSTL
Sbjct: 1842 LKLVSTL 1848



>NP_940870
          Length = 1243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IKLVSTLT 9
            I L+STLT
Sbjct: 1191 IHLISTLT 1198



>XP_006723382
          Length = 5027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    IKLVSTL 8
            +KLVSTL
Sbjct: 1842 LKLVSTL 1848



>XP_006723381
          Length = 5031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    IKLVSTL 8
            +KLVSTL
Sbjct: 1841 LKLVSTL 1847



>XP_006723380
          Length = 5032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    IKLVSTL 8
            +KLVSTL
Sbjct: 1842 LKLVSTL 1848



>XP_006715494
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IKLVSTLT 9
           I L+STLT
Sbjct: 965 IHLISTLT 972



>XP_006715493
          Length = 1243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IKLVSTLT 9
            I L+STLT
Sbjct: 1191 IHLISTLT 1198



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.122    0.269 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 250,768
Number of extensions: 279
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)