Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003626                                                              17    3301
NP_001094871                                                           17    3301
XP_006723390                                                           17    3301
XP_005270313                                                           17    3301
XP_005270312                                                           17    3301
XP_006718109                                                           17    3301
NP_055672                                                              17    4312
NP_060922                                                              17    4312
XP_006715761                                                           17    4312
XP_006711756                                                           17    4312
XP_005245738                                                           17    4312
XP_006711755                                                           17    4312
XP_005245737                                                           17    4312
NP_689856                                                              16    5631
NP_001004470                                                           16    5631
NP_060787                                                              16    5631
XP_005248229                                                           16    5631
XP_006714030                                                           16    5631
NP_002541                                                              16    7355
NP_001004125                                                           16    7355
NP_001135918                                                           16    7355
NP_079357                                                              16    7355
NP_065208                                                              16    7355
NP_002879                                                              16    7355
NP_996846                                                              16    7355
NP_000557                                                              16    7355
NP_001004340                                                           16    7355
NP_976307                                                              16    7355
NP_001017986                                                           16    7355
NP_001231839                                                           16    7355
XP_005273533                                                           16    7355
XP_005247743                                                           16    7355
XP_005245015                                                           16    7355
XP_005245014                                                           16    7355
NP_065210                                                              16    7355
NP_065209                                                              16    7355
NP_000028                                                              16    7355
NP_001073946                                                           15    9605
NP_055068                                                              15    9605
NP_001156750                                                           15    9605
NP_001156751                                                           15    9605
NP_001272808                                                           15    9605
NP_001272807                                                           15    9605
NP_005185                                                              15    9605
NP_060109                                                              15    9605
NP_115486                                                              15    9605
NP_001116151                                                           15    9605
NP_036337                                                              15    9605
NP_995312                                                              15    9605
NP_995309                                                              15    9605
NP_000669                                                              15    9605
XP_006726609                                                           15    9605
XP_005276342                                                           15    9605
XP_006726193                                                           15    9605
XP_006726105                                                           15    9605
XP_006726004                                                           15    9605
XP_006725915                                                           15    9605
XP_006725808                                                           15    9605
XP_006725589                                                           15    9605
XP_006725111                                                           15    9605
XP_006724788                                                           15    9605
XP_006723441                                                           15    9605
XP_005259313                                                           15    9605
XP_006719787                                                           15    9605
XP_006715273                                                           15    9605
XP_005266009                                                           15    9605
XP_006714961                                                           15    9605
XP_006714960                                                           15    9605
XP_005266007                                                           15    9605
XP_006714321                                                           15    9605
XP_006714320                                                           15    9605
XP_006714319                                                           15    9605
XP_006710027                                                           15    9605
NP_077286                                                              15    9605
>NP_003626
          Length = 883

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SGTPLALRA 9
           S TPLALR+
Sbjct: 737 SQTPLALRS 745
>NP_001094871
          Length = 348

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  GTPLALR 8
          GTPLAL+
Sbjct: 85 GTPLALK 91
>XP_006723390
          Length = 348

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  GTPLALR 8
          GTPLAL+
Sbjct: 85 GTPLALK 91
>XP_005270313
          Length = 509

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SGTPLALRA 9
           S TPLALR+
Sbjct: 363 SQTPLALRS 371
>XP_005270312
          Length = 815

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SGTPLALRA 9
           S TPLALR+
Sbjct: 737 SQTPLALRS 745
>XP_006718109
          Length = 821

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SGTPLALRA 9
           S TPLALR+
Sbjct: 675 SQTPLALRS 683
>NP_055672
          Length = 815

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGTPLALRA 9
           SG P ALRA
Sbjct: 537 SGVPEALRA 545
>NP_060922
          Length = 141

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  SGTPLALRA 9
          SG+ LALRA
Sbjct: 74 SGSSLALRA 82
>XP_006715761
          Length = 361

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SGTPLALRA 9
          SGT L LRA
Sbjct: 11 SGTSLGLRA 19
>XP_006711756
          Length = 985

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGTPLALRA 9
           SG P ALRA
Sbjct: 537 SGVPEALRA 545
>XP_005245738
          Length = 1014

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGTPLALRA 9
           SG P ALRA
Sbjct: 500 SGVPEALRA 508
>XP_006711755
          Length = 1051

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGTPLALRA 9
           SG P ALRA
Sbjct: 537 SGVPEALRA 545
>XP_005245737
          Length = 1051

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGTPLALRA 9
           SG P ALRA
Sbjct: 537 SGVPEALRA 545
>NP_689856
          Length = 1749

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SGTPLALRA 9
            +GTPL L A
Sbjct: 1252 AGTPLGLMA 1260
>NP_001004470
          Length = 398

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  GTPLALR 8
          GTP ALR
Sbjct: 46 GTPAALR 52
>NP_060787
          Length = 526

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GTPLALRA 9
           G+P ALRA
Sbjct: 251 GSPTALRA 258
>XP_005248229
          Length = 461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GTPLALRA 9
           G+P ALRA
Sbjct: 186 GSPTALRA 193
>XP_006714030
          Length = 495

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GTPLALRA 9
           G+P ALRA
Sbjct: 220 GSPTALRA 227
>NP_002541
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SGTPLAL 7
           +GTP+AL
Sbjct: 210 AGTPMAL 216
>NP_001004125
          Length = 212

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GTPLALRA 9
           G+P ALRA
Sbjct: 152 GSPRALRA 159
>NP_001135918
          Length = 1897

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TPLALR 8
            TPLALR
Sbjct: 1421 TPLALR 1426
>NP_079357
          Length = 1898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SGTPLALR 8
            SGTPL+ +
Sbjct: 1887 SGTPLSFK 1894
>NP_065208
          Length = 1856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TPLALR 8
            TPLALR
Sbjct: 1380 TPLALR 1385
>NP_002879
          Length = 228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SGTPLALR 8
          SG+P ALR
Sbjct: 74 SGSPSALR 81
>NP_996846
          Length = 294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SGTPLALR 8
          SG+P ALR
Sbjct: 74 SGSPSALR 81
>NP_000557
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GTPLALR 8
           G PLALR
Sbjct: 117 GEPLALR 123
>NP_001004340
          Length = 188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  GTPLALR 8
          G PLALR
Sbjct: 25 GEPLALR 31
>NP_976307
          Length = 247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SGTPLAL 7
           SGTP+A+
Sbjct: 135 SGTPIAV 141
>NP_001017986
          Length = 280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GTPLALR 8
           G PLALR
Sbjct: 117 GEPLALR 123
>NP_001231839
          Length = 224

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GTPLALR 8
           G PLALR
Sbjct: 117 GEPLALR 123
>XP_005273533
          Length = 1921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TPLALR 8
            TPLALR
Sbjct: 1421 TPLALR 1426
>XP_005247743
          Length = 436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGTPLALR 8
           SG+P ALR
Sbjct: 220 SGSPSALR 227
>XP_005245015
          Length = 282

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  GTPLALR 8
          G PLALR
Sbjct: 25 GEPLALR 31
>XP_005245014
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GTPLALR 8
           G PLALR
Sbjct: 118 GEPLALR 124
>NP_065210
          Length = 1719

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TPLALR 8
            TPLALR
Sbjct: 1380 TPLALR 1385
>NP_065209
          Length = 1881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TPLALR 8
            TPLALR
Sbjct: 1380 TPLALR 1385
>NP_000028
          Length = 1880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TPLALR 8
            TPLALR
Sbjct: 1380 TPLALR 1385
>NP_001073946
          Length = 2699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SGTPLAL 7
            +GTPLA+
Sbjct: 2299 TGTPLAV 2305
>NP_055068
          Length = 2725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SGTPLAL 7
            +GTPLA+
Sbjct: 2320 TGTPLAV 2326
>NP_001156750
          Length = 2732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SGTPLAL 7
            +GTPLA+
Sbjct: 2327 TGTPLAV 2333
>NP_001156751
          Length = 2731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SGTPLAL 7
            +GTPLA+
Sbjct: 2326 TGTPLAV 2332
>NP_001272808
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SGTPLALRA 9
          +G P ALRA
Sbjct: 3  AGFPYALRA 11
>NP_001272807
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SGTPLALRA 9
           +G P ALRA
Sbjct: 178 AGFPYALRA 186
>NP_005185
          Length = 345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SGTPLALRA 9
           +G P ALRA
Sbjct: 201 AGFPYALRA 209
>NP_060109
          Length = 2916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTPLALRA 9
            GTPLA+ A
Sbjct: 2529 GTPLAVFA 2536
>NP_115486
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  GTPLALRA 9
          G PL LRA
Sbjct: 53 GPPLLLRA 60
>NP_001116151
          Length = 2765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SGTPLAL 7
            +GTPLA+
Sbjct: 2363 TGTPLAV 2369
>NP_036337
          Length = 286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SGTPLAL 7
           +GTPL+L
Sbjct: 196 AGTPLSL 202
>NP_995312
          Length = 59

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SGTPLALRA 9
          +GTPL + A
Sbjct: 44 AGTPLCISA 52
>NP_995309
          Length = 66

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SGTPLALRA 9
          +GTPL + A
Sbjct: 51 AGTPLCISA 59
>NP_000669
          Length = 572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   GTPLALRA 9
           G PLAL A
Sbjct: 459 GAPLALTA 466
>XP_006726609
          Length = 2838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SGTPLALR 8
            SG+PL L+
Sbjct: 2739 SGSPLTLK 2746
>XP_005276342
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SGTPLAL 7
           SG PLAL
Sbjct: 224 SGRPLAL 230
>XP_006726193
          Length = 59

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SGTPLALRA 9
          +GTPL + A
Sbjct: 44 AGTPLCISA 52
>XP_006726105
          Length = 59

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SGTPLALRA 9
          +GTPL + A
Sbjct: 44 AGTPLCISA 52
>XP_006726004
          Length = 59

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SGTPLALRA 9
          +GTPL + A
Sbjct: 44 AGTPLCISA 52
>XP_006725915
          Length = 59

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SGTPLALRA 9
          +GTPL + A
Sbjct: 44 AGTPLCISA 52
>XP_006725808
          Length = 59

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SGTPLALRA 9
          +GTPL + A
Sbjct: 44 AGTPLCISA 52
>XP_006725589
          Length = 59

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SGTPLALRA 9
          +GTPL + A
Sbjct: 44 AGTPLCISA 52
>XP_006725111
          Length = 59

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SGTPLALRA 9
          +GTPL + A
Sbjct: 44 AGTPLCISA 52
>XP_006724788
          Length = 2570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SGTPLAL 7
            +GTPLA+
Sbjct: 2165 TGTPLAV 2171
>XP_006723441
          Length = 279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  SGTPLAL 7
          SG PLAL
Sbjct: 25 SGQPLAL 31
>XP_005259313
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SGTPLAL 7
           SG PLAL
Sbjct: 110 SGQPLAL 116
>XP_006719787
          Length = 2838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SGTPLALR 8
            SG+PL L+
Sbjct: 2739 SGSPLTLK 2746
>XP_006715273
          Length = 59

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SGTPLALRA 9
          +GTPL + A
Sbjct: 44 AGTPLCISA 52
>XP_005266009
          Length = 2378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SGTPLAL 7
            +GTPLA+
Sbjct: 1976 TGTPLAV 1982
>XP_006714961
          Length = 2548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SGTPLAL 7
            +GTPLA+
Sbjct: 2146 TGTPLAV 2152
>XP_006714960
          Length = 2758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SGTPLAL 7
            +GTPLA+
Sbjct: 2356 TGTPLAV 2362
>XP_005266007
          Length = 2765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SGTPLAL 7
            +GTPLA+
Sbjct: 2363 TGTPLAV 2369
>XP_006714321
          Length = 2713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SGTPLAL 7
            +GTPLA+
Sbjct: 2313 TGTPLAV 2319
>XP_006714320
          Length = 2720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SGTPLAL 7
            +GTPLA+
Sbjct: 2320 TGTPLAV 2326
>XP_006714319
          Length = 2721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SGTPLAL 7
            +GTPLA+
Sbjct: 2321 TGTPLAV 2327
>XP_006710027
          Length = 2837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SGTPLALR 8
            SG+PL L+
Sbjct: 2738 SGSPLTLK 2745
>NP_077286
          Length = 279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  SGTPLAL 7
          SG PLAL
Sbjct: 25 SGQPLAL 31
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.128    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 724,988
Number of extensions: 1277
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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