Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     665
NP_001185763                                                           19     665
NP_055459                                                              19     665
XP_006726410                                                           19     665
XP_006711719                                                           19     665
XP_006711718                                                           19     665
XP_006711717                                                           19     665
XP_006711716                                                           19     665
XP_006711715                                                           19     665
XP_006711714                                                           19     665
XP_006711713                                                           19     665
XP_006711712                                                           19     665
XP_006711711                                                           19     665
XP_006711710                                                           19     665
XP_006711709                                                           19     665
XP_005277503                                                           19     665
XP_005273038                                                           19     665
XP_006711708                                                           19     665
XP_005277500                                                           19     665
XP_006711707                                                           19     665
XP_005277499                                                           19     665
XP_006711706                                                           19     665
XP_006711705                                                           19     665
XP_006711164                                                           19     665
XP_006710143                                                           19     665
XP_006710142                                                           19     665
XP_006710141                                                           19     665
NP_001269788                                                           18    1135
NP_001193941                                                           16    5631
NP_002623                                                              16    5631
NP_001007254                                                           16    5631
XP_005267818                                                           16    5631
NP_056046                                                              16    7355
XP_006718233                                                           16    7355
NP_006077                                                              15    9605
NP_821080                                                              15    9605
NP_001276052                                                           15    9605
NP_006078                                                              15    9605
NP_821133                                                              15    9605
NP_001276058                                                           15    9605
NP_001276060                                                           15    9605
NP_001276059                                                           15    9605
NP_001276056                                                           15    9605
NP_115914                                                              15    9605
NP_001184110                                                           15    9605
NP_110400                                                              15    9605
NP_817124                                                              15    9605
NP_055785                                                              15    9605
NP_001186217                                                           15    9605
NP_001186216                                                           15    9605
NP_001186215                                                           15    9605
NP_001186214                                                           15    9605
NP_001008781                                                           15    9605
NP_001008489                                                           15    9605
NP_001060                                                              15    9605
NP_001191443                                                           15    9605
NP_001191446                                                           15    9605
NP_001191445                                                           15    9605
XP_006724942                                                           15    9605
XP_005258216                                                           15    9605
XP_006718827                                                           15    9605
XP_005250260                                                           15    9605
XP_005245027                                                           15    9605
XP_006710331                                                           15    9605
NP_690852                                                              15    9605
NP_006079                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1577 SDMDIVSEY 1585
>NP_001185763
          Length = 2362

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1621 SDMDIVSEY 1629
>NP_055459
          Length = 2346

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1621 SDMDIVSEY 1629
>XP_006726410
          Length = 2087

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1424 SDMDIVSEY 1432
>XP_006711719
          Length = 2302

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1577 SDMDIVSEY 1585
>XP_006711718
          Length = 1436

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SGMDIVSEY 9
           S MDIVSEY
Sbjct: 628 SDMDIVSEY 636
>XP_006711717
          Length = 2385

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1577 SDMDIVSEY 1585
>XP_006711716
          Length = 2411

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1686 SDMDIVSEY 1694
>XP_006711715
          Length = 2428

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1620 SDMDIVSEY 1628
>XP_006711714
          Length = 2429

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1621 SDMDIVSEY 1629
>XP_006711713
          Length = 2432

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1624 SDMDIVSEY 1632
>XP_006711712
          Length = 2473

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1784 SDMDIVSEY 1792
>XP_006711711
          Length = 2482

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1674 SDMDIVSEY 1682
>XP_006711710
          Length = 2494

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1686 SDMDIVSEY 1694
>XP_006711709
          Length = 2495

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1687 SDMDIVSEY 1695
>XP_005277503
          Length = 2498

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1784 SDMDIVSEY 1792
>XP_005273038
          Length = 2509

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1784 SDMDIVSEY 1792
>XP_006711708
          Length = 2512

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1784 SDMDIVSEY 1792
>XP_005277500
          Length = 2525

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1784 SDMDIVSEY 1792
>XP_006711707
          Length = 2553

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1784 SDMDIVSEY 1792
>XP_005277499
          Length = 2561

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1784 SDMDIVSEY 1792
>XP_006711706
          Length = 2591

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1783 SDMDIVSEY 1791
>XP_006711705
          Length = 2592

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1784 SDMDIVSEY 1792
>XP_006711164
          Length = 2087

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGMDIVSEY 9
            S MDIVSEY
Sbjct: 1424 SDMDIVSEY 1432
>XP_006710143
          Length = 562

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SGMDIVSEY 9
           S MDIVSEY
Sbjct: 463 SDMDIVSEY 471
>XP_006710142
          Length = 671

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SGMDIVSEY 9
           S MDIVSEY
Sbjct: 572 SDMDIVSEY 580
>XP_006710141
          Length = 672

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SGMDIVSEY 9
           S MDIVSEY
Sbjct: 573 SDMDIVSEY 581
>NP_001269788
          Length = 459

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   GMDIVSEY 9
           G+D+VSEY
Sbjct: 443 GVDVVSEY 450
>NP_001193941
          Length = 149

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  MDIVSEY 9
          +D+VSEY
Sbjct: 59 VDVVSEY 65
>NP_002623
          Length = 170

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  MDIVSEY 9
          +D+VSEY
Sbjct: 59 VDVVSEY 65
>NP_001007254
          Length = 604

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SGMDIVSEY 9
           SG D+VS Y
Sbjct: 112 SGKDVVSLY 120
>XP_005267818
          Length = 169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  MDIVSEY 9
          +D+VSEY
Sbjct: 58 VDVVSEY 64
>NP_056046
          Length = 1436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    MDIVSEY 9
            +D+VSEY
Sbjct: 1351 VDLVSEY 1357
>XP_006718233
          Length = 782

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   MDIVSEY 9
           +D+VSEY
Sbjct: 697 VDLVSEY 703
>NP_006077
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 417 DLVSEY 422
>NP_821080
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 417 DLVSEY 422
>NP_001276052
          Length = 495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 468 DLVSEY 473
>NP_006078
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 417 DLVSEY 422
>NP_821133
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 417 DLVSEY 422
>NP_001276058
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 417 DLVSEY 422
>NP_001276060
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 345 DLVSEY 350
>NP_001276059
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 345 DLVSEY 350
>NP_001276056
          Length = 489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 462 DLVSEY 467
>NP_115914
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 417 DLVSEY 422
>NP_001184110
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 345 DLVSEY 350
>NP_110400
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 417 DLVSEY 422
>NP_817124
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 417 DLVSEY 422
>NP_055785
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   MDIVSEY 9
           +DI++EY
Sbjct: 657 LDIIAEY 663
>NP_001186217
          Length = 241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SGMDIVS 7
           SG+DI+S
Sbjct: 227 SGVDIIS 233
>NP_001186216
          Length = 241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SGMDIVS 7
           SG+DI+S
Sbjct: 227 SGVDIIS 233
>NP_001186215
          Length = 241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SGMDIVS 7
           SG+DI+S
Sbjct: 227 SGVDIIS 233
>NP_001186214
          Length = 241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SGMDIVS 7
           SG+DI+S
Sbjct: 227 SGVDIIS 233
>NP_001008781
          Length = 4557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GMDIVSEY 9
            G DI SEY
Sbjct: 4398 GYDIDSEY 4405
>NP_001008489
          Length = 241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SGMDIVS 7
           SG+DI+S
Sbjct: 227 SGVDIIS 233
>NP_001060
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 417 DLVSEY 422
>NP_001191443
          Length = 714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   MDIVSEY 9
           +DI++EY
Sbjct: 579 LDIIAEY 585
>NP_001191446
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   MDIVSEY 9
           +DI++EY
Sbjct: 617 LDIIAEY 623
>NP_001191445
          Length = 748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   MDIVSEY 9
           +DI++EY
Sbjct: 613 LDIIAEY 619
>XP_006724942
          Length = 641

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   MDIVSEY 9
           MDI+S Y
Sbjct: 559 MDIISTY 565
>XP_005258216
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 271 DLVSEY 276
>XP_006718827
          Length = 3479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GMDIVSEY 9
            G DI SEY
Sbjct: 3320 GYDIDSEY 3327
>XP_005250260
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  SGMDIVSEY 9
          SG++++SE+
Sbjct: 29 SGLELLSEH 37
>XP_005245027
          Length = 794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   MDIVSEY 9
           +DI++EY
Sbjct: 657 LDIIAEY 663
>XP_006710331
          Length = 641

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   MDIVSEY 9
           MDI+S Y
Sbjct: 559 MDIISTY 565
>NP_690852
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  SGMDIVSEY 9
          SG++++SE+
Sbjct: 29 SGLELLSEH 37
>NP_006079
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DIVSEY 9
           D+VSEY
Sbjct: 417 DLVSEY 422
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.130    0.342 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 472,925
Number of extensions: 1118
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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