Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001188267                                                           17    3301
NP_001188269                                                           17    3301
NP_002958                                                              17    3301
NP_001188268                                                           17    3301
NP_055464                                                              17    3301
NP_001275701                                                           17    3301
NP_004561                                                              17    3301
NP_001275703                                                           17    3301
XP_006722902                                                           17    3301
XP_005253450                                                           17    3301
XP_006719151                                                           17    3301
XP_005252905                                                           17    3301
XP_005252904                                                           17    3301
NP_036326                                                              17    3301
NP_078858                                                              17    4312
NP_001278232                                                           17    4312
NP_001278214                                                           17    4312
NP_060109                                                              17    4312
NP_004217                                                              16    7355
NP_005236                                                              16    7355
NP_079111                                                              16    7355
XP_005276966                                                           16    7355
XP_005257746                                                           16    7355
XP_005270370                                                           16    7355
XP_006717680                                                           16    7355
XP_006714202                                                           16    7355
XP_005262892                                                           16    7355
XP_005262891                                                           16    7355
NP_694579                                                              16    7355
NP_113689                                                              16    7355
NP_061731                                                              16    7355
NP_061885                                                              15    9605
NP_001243716                                                           15    9605
NP_001846                                                              15    9605
NP_001243399                                                           15    9605
NP_001137293                                                           15    9605
NP_001275918                                                           15    9605
NP_001159451                                                           15    9605
NP_057425                                                              15    9605
NP_056164                                                              15    9605
NP_071896                                                              15    9605
NP_001258113                                                           15    9605
NP_001258112                                                           15    9605
NP_001034794                                                           15    9605
XP_006724667                                                           15    9605
XP_006724666                                                           15    9605
XP_006724665                                                           15    9605
XP_006724664                                                           15    9605
XP_006724663                                                           15    9605
XP_006724662                                                           15    9605
XP_006719159                                                           15    9605
XP_006719157                                                           15    9605
XP_006719156                                                           15    9605
XP_006719155                                                           15    9605
XP_005253457                                                           15    9605
XP_006719154                                                           15    9605
XP_005253456                                                           15    9605
XP_005253455                                                           15    9605
XP_006719153                                                           15    9605
XP_006719152                                                           15    9605
XP_006717953                                                           15    9605
XP_006717952                                                           15    9605
XP_006717951                                                           15    9605
XP_006717950                                                           15    9605
XP_006717949                                                           15    9605
XP_006717948                                                           15    9605
XP_005249030                                                           15    9605
XP_005249029                                                           15    9605
>NP_001188267
          Length = 917

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           SGL STTR+
Sbjct: 411 SGLSSTTRA 419
>NP_001188269
          Length = 848

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           SGL STTR+
Sbjct: 342 SGLSSTTRA 350
>NP_002958
          Length = 915

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           SGL STTR+
Sbjct: 411 SGLSSTTRA 419
>NP_001188268
          Length = 916

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           SGL STTR+
Sbjct: 411 SGLSSTTRA 419
>NP_055464
          Length = 953

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           SGL STTR+
Sbjct: 412 SGLSSTTRA 420
>NP_001275701
          Length = 1486

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGLLSTTRS 9
            S LLSTTRS
Sbjct: 1237 SCLLSTTRS 1245
>NP_004561
          Length = 1445

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGLLSTTRS 9
            S LLSTTRS
Sbjct: 1196 SCLLSTTRS 1204
>NP_001275703
          Length = 1264

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGLLSTTRS 9
            S LLSTTRS
Sbjct: 1015 SCLLSTTRS 1023
>XP_006722902
          Length = 914

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           SGL STTR+
Sbjct: 411 SGLSSTTRA 419
>XP_005253450
          Length = 1486

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGLLSTTRS 9
            S LLSTTRS
Sbjct: 1237 SCLLSTTRS 1245
>XP_006719151
          Length = 1486

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SGLLSTTRS 9
            S LLSTTRS
Sbjct: 1237 SCLLSTTRS 1245
>XP_005252905
          Length = 1854

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SGLLSTT 7
           SGLLSTT
Sbjct: 742 SGLLSTT 748
>XP_005252904
          Length = 1855

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SGLLSTT 7
           SGLLSTT
Sbjct: 742 SGLLSTT 748
>NP_036326
          Length = 1849

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SGLLSTT 7
           SGLLSTT
Sbjct: 736 SGLLSTT 742
>NP_078858
          Length = 4981

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SGLLSTTR 8
            +G+LSTTR
Sbjct: 3563 AGVLSTTR 3570
>NP_001278232
          Length = 4983

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SGLLSTTR 8
            +G+LSTTR
Sbjct: 3565 AGVLSTTR 3572
>NP_001278214
          Length = 4982

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SGLLSTTR 8
            +G+LSTTR
Sbjct: 3565 AGVLSTTR 3572
>NP_060109
          Length = 2916

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SGLLSTTRS 9
            SG LSTTR+
Sbjct: 1427 SGELSTTRA 1435

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SGLLSTT 7
            SGLL+TT
Sbjct: 1218 SGLLTTT 1224
>NP_004217
          Length = 372

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  SGLLSTT 7
          SGLL+TT
Sbjct: 12 SGLLTTT 18
>NP_005236
          Length = 4588

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SGLLSTT 7
            SG+LSTT
Sbjct: 2029 SGVLSTT 2035
>NP_079111
          Length = 697

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLLSTTRS 9
           G+LS TRS
Sbjct: 120 GVLSVTRS 127
>XP_005276966
          Length = 699

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLLSTTRS 9
           G+LS TRS
Sbjct: 120 GVLSVTRS 127
>XP_005257746
          Length = 699

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLLSTTRS 9
           G+LS TRS
Sbjct: 120 GVLSVTRS 127
>XP_005270370
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLLSTT 7
           SGLL+TT
Sbjct: 193 SGLLNTT 199
>XP_006717680
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLLSTT 7
           SGLL+TT
Sbjct: 193 SGLLNTT 199
>XP_006714202
          Length = 4588

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SGLLSTT 7
            SG+LSTT
Sbjct: 2029 SGVLSTT 2035
>XP_005262892
          Length = 4600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SGLLSTT 7
            SG+LSTT
Sbjct: 2029 SGVLSTT 2035
>XP_005262891
          Length = 4600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SGLLSTT 7
            SG+LSTT
Sbjct: 2029 SGVLSTT 2035
>NP_694579
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLLSTT 7
           SGLL+TT
Sbjct: 193 SGLLNTT 199
>NP_113689
          Length = 816

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           +G +STTRS
Sbjct: 627 TGEISTTRS 635
>NP_061731
          Length = 936

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           +G +STTRS
Sbjct: 627 TGEISTTRS 635
>NP_061885
          Length = 1116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLLSTTR 8
           +GLLST R
Sbjct: 699 NGLLSTCR 706
>NP_001243716
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLLSTTR 8
           +GLLST R
Sbjct: 618 NGLLSTCR 625
>NP_001846
          Length = 1388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SGLLSTTRS 9
            +GLLST R+
Sbjct: 1244 AGLLSTYRA 1252
>NP_001243399
          Length = 1282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLLSTTR 8
           +GLLST R
Sbjct: 802 NGLLSTCR 809
>NP_001137293
          Length = 1174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLLSTTR 8
           +GLLST R
Sbjct: 757 NGLLSTCR 764
>NP_001275918
          Length = 2286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SGLLSTTRS 9
            SGLL  TR+
Sbjct: 1000 SGLLELTRA 1008
>NP_001159451
          Length = 1994

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SGLLSTTRS 9
           SGLL  TR+
Sbjct: 692 SGLLELTRA 700
>NP_057425
          Length = 2302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SGLLSTTRS 9
            SGLL  TR+
Sbjct: 1000 SGLLELTRA 1008
>NP_056164
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLLSTT 7
           GLLSTT
Sbjct: 641 GLLSTT 646
>NP_071896
          Length = 800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLLSTTR 8
           G+L+TTR
Sbjct: 644 GILATTR 650
>NP_001258113
          Length = 1034

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           SG+LST+ S
Sbjct: 463 SGVLSTSTS 471
>NP_001258112
          Length = 962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           SG+LST+ S
Sbjct: 391 SGVLSTSTS 399
>NP_001034794
          Length = 1431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           SG+LST+ S
Sbjct: 860 SGVLSTSTS 868
>XP_006724667
          Length = 1387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           SG+LST+ S
Sbjct: 816 SGVLSTSTS 824
>XP_006724666
          Length = 1387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           SG+LST+ S
Sbjct: 816 SGVLSTSTS 824
>XP_006724665
          Length = 1431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           SG+LST+ S
Sbjct: 860 SGVLSTSTS 868
>XP_006724664
          Length = 1431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           SG+LST+ S
Sbjct: 860 SGVLSTSTS 868
>XP_006724663
          Length = 1431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           SG+LST+ S
Sbjct: 860 SGVLSTSTS 868
>XP_006724662
          Length = 1431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLLSTTRS 9
           SG+LST+ S
Sbjct: 860 SGVLSTSTS 868
>XP_006719159
          Length = 1276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLLSTTR 8
           +GLLST R
Sbjct: 796 NGLLSTCR 803
>XP_006719157
          Length = 1128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLLSTTR 8
           +GLLST R
Sbjct: 648 NGLLSTCR 655
>XP_006719156
          Length = 1151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLLSTTR 8
           +GLLST R
Sbjct: 671 NGLLSTCR 678
>XP_006719155
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLLSTTR 8
           +GLLST R
Sbjct: 756 NGLLSTCR 763
>XP_005253457
          Length = 1179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLLSTTR 8
           +GLLST R
Sbjct: 699 NGLLSTCR 706
>XP_006719154
          Length = 1197

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLLSTTR 8
           +GLLST R
Sbjct: 717 NGLLSTCR 724
>XP_005253456
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLLSTTR 8
           +GLLST R
Sbjct: 726 NGLLSTCR 733
>XP_005253455
          Length = 1218

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLLSTTR 8
           +GLLST R
Sbjct: 738 NGLLSTCR 745
>XP_006719153
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLLSTTR 8
           +GLLST R
Sbjct: 744 NGLLSTCR 751
>XP_006719152
          Length = 1236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLLSTTR 8
           +GLLST R
Sbjct: 756 NGLLSTCR 763
>XP_006717953
          Length = 2008

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SGLLSTTRS 9
           SGLL  TR+
Sbjct: 692 SGLLELTRA 700
>XP_006717952
          Length = 2300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SGLLSTTRS 9
            SGLL  TR+
Sbjct: 1000 SGLLELTRA 1008
>XP_006717951
          Length = 2315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SGLLSTTRS 9
            SGLL  TR+
Sbjct: 1000 SGLLELTRA 1008
>XP_006717950
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SGLLSTTRS 9
            SGLL  TR+
Sbjct: 1000 SGLLELTRA 1008
>XP_006717949
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SGLLSTTRS 9
            SGLL  TR+
Sbjct: 1000 SGLLELTRA 1008
>XP_006717948
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SGLLSTTRS 9
            SGLL  TR+
Sbjct: 1000 SGLLELTRA 1008
>XP_005249030
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLLSTT 7
           GLLSTT
Sbjct: 641 GLLSTT 646
>XP_005249029
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLLSTT 7
           GLLSTT
Sbjct: 641 GLLSTT 646
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.113    0.268 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 373,360
Number of extensions: 570
Number of successful extensions: 69
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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