Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001096654                                                           18    1482
NP_001264242                                                           18    1482
XP_005264309                                                           17    3301
XP_005264308                                                           17    3301
XP_006712048                                                           17    3301
NP_001129978                                                           17    4312
NP_689658                                                              16    5631
NP_068587                                                              16    5631
NP_851996                                                              16    5631
NP_001229537                                                           16    5631
NP_001070150                                                           16    5631
NP_001229536                                                           16    5631
NP_000606                                                              16    5631
NP_005468                                                              16    7355
NP_001193858                                                           16    7355
NP_001193861                                                           16    7355
NP_001127                                                              16    7355
NP_001017975                                                           16    7355
NP_060045                                                              16    7355
NP_001136113                                                           16    7355
XP_005256627                                                           16    7355
XP_006721558                                                           16    7355
XP_006721557                                                           16    7355
XP_006721556                                                           16    7355
XP_005256626                                                           16    7355
XP_006719805                                                           16    7355
XP_005266236                                                           16    7355
XP_005266234                                                           16    7355
XP_005266233                                                           16    7355
XP_006719804                                                           16    7355
XP_005266232                                                           16    7355
XP_005266231                                                           16    7355
XP_005266230                                                           16    7355
XP_005266229                                                           16    7355
XP_005266228                                                           16    7355
NP_659477                                                              16    7355
NP_004487                                                              15    9605
NP_001273331                                                           15    9605
NP_000237                                                              15    9605
NP_056093                                                              15    9605
NP_001243793                                                           15    9605
NP_001243794                                                           15    9605
NP_001980                                                              15    9605
NP_055602                                                              15    9605
NP_001244286                                                           15    9605
NP_001078846                                                           15    9605
NP_002494                                                              15    9605
NP_005512                                                              15    9605
NP_001073927                                                           15    9605
NP_079452                                                              15    9605
NP_001182446                                                           15    9605
NP_005193                                                              15    9605
XP_006723617                                                           15    9605
XP_005260737                                                           15    9605
XP_006723616                                                           15    9605
XP_006723615                                                           15    9605
XP_005260735                                                           15    9605
XP_006720946                                                           15    9605
XP_005255380                                                           15    9605
XP_006720945                                                           15    9605
XP_006720944                                                           15    9605
XP_005255378                                                           15    9605
XP_005255377                                                           15    9605
XP_006720943                                                           15    9605
XP_005249697                                                           15    9605
XP_005249696                                                           15    9605
XP_005266932                                                           15    9605
XP_006715469                                                           15    9605
XP_005266931                                                           15    9605
XP_006714680                                                           15    9605
XP_005270536                                                           15    9605
XP_005270535                                                           15    9605
XP_005270534                                                           15    9605
>NP_001096654
          Length = 1196

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SGLGSLSAA 9
           SGLGSLS A
Sbjct: 660 SGLGSLSPA 668
>NP_001264242
          Length = 1419

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SGLGSLSAA 9
           SGLGSLS A
Sbjct: 883 SGLGSLSPA 891
>XP_005264309
          Length = 1324

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    GLGSLSA 8
            GLGSLSA
Sbjct: 1042 GLGSLSA 1048
>XP_005264308
          Length = 1218

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   GLGSLSA 8
           GLGSLSA
Sbjct: 936 GLGSLSA 942
>XP_006712048
          Length = 1249

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   GLGSLSA 8
           GLGSLSA
Sbjct: 967 GLGSLSA 973
>NP_001129978
          Length = 552

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   GLGSLSAA 9
           G+GS+SAA
Sbjct: 441 GIGSVSAA 448
>NP_689658
          Length = 710

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SGLGSLSA 8
           SGL SLSA
Sbjct: 504 SGLASLSA 511
>NP_068587
          Length = 580

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   GLGSLSAA 9
           GLG++SAA
Sbjct: 336 GLGAVSAA 343
>NP_851996
          Length = 858

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLGSLSAA 9
           GLG +SAA
Sbjct: 593 GLGEISAA 600
>NP_001229537
          Length = 726

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLGSLSAA 9
           GLG +SAA
Sbjct: 583 GLGEISAA 590
>NP_001070150
          Length = 761

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLGSLSAA 9
           GLG +SAA
Sbjct: 583 GLGEISAA 590
>NP_001229536
          Length = 884

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLGSLSAA 9
           GLG +SAA
Sbjct: 619 GLGEISAA 626
>NP_000606
          Length = 848

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLGSLSAA 9
           GLG +SAA
Sbjct: 583 GLGEISAA 590
>NP_005468
          Length = 1203

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLGSLSA 8
           SGLG+L A
Sbjct: 812 SGLGNLGA 819
>NP_001193858
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLGSLSAA 9
           SGLG+L+ A
Sbjct: 352 SGLGTLALA 360
>NP_001193861
          Length = 390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLGSLSAA 9
           SGLG+L+ A
Sbjct: 322 SGLGTLALA 330
>NP_001127
          Length = 404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLGSLSAA 9
           SGLG+L+ A
Sbjct: 336 SGLGTLALA 344
>NP_001017975
          Length = 1435

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLGSLSA 8
           +GLGSL A
Sbjct: 256 NGLGSLKA 263
>NP_060045
          Length = 1419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLGSLS 7
           +GLGSLS
Sbjct: 878 NGLGSLS 884
>NP_001136113
          Length = 1045

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GLGSLSA 8
           GLGSLS+
Sbjct: 691 GLGSLSS 697
>XP_005256627
          Length = 899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLGSLS 7
           +GLGSLS
Sbjct: 878 NGLGSLS 884
>XP_006721558
          Length = 909

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLGSLS 7
           +GLGSLS
Sbjct: 878 NGLGSLS 884
>XP_006721557
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLGSLS 7
           +GLGSLS
Sbjct: 878 NGLGSLS 884
>XP_006721556
          Length = 1357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLGSLS 7
           +GLGSLS
Sbjct: 816 NGLGSLS 822
>XP_005256626
          Length = 1388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLGSLS 7
           +GLGSLS
Sbjct: 847 NGLGSLS 853
>XP_006719805
          Length = 1009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GLGSLSA 8
           GLGSLS+
Sbjct: 655 GLGSLSS 661
>XP_005266236
          Length = 986

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GLGSLSA 8
           GLGSLS+
Sbjct: 632 GLGSLSS 638
>XP_005266234
          Length = 1043

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GLGSLSA 8
           GLGSLS+
Sbjct: 689 GLGSLSS 695
>XP_005266233
          Length = 1044

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GLGSLSA 8
           GLGSLS+
Sbjct: 690 GLGSLSS 696
>XP_006719804
          Length = 1051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GLGSLSA 8
           GLGSLS+
Sbjct: 697 GLGSLSS 703
>XP_005266232
          Length = 1062

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GLGSLSA 8
           GLGSLS+
Sbjct: 708 GLGSLSS 714
>XP_005266231
          Length = 1062

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GLGSLSA 8
           GLGSLS+
Sbjct: 708 GLGSLSS 714
>XP_005266230
          Length = 1083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GLGSLSA 8
           GLGSLS+
Sbjct: 729 GLGSLSS 735
>XP_005266229
          Length = 1084

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GLGSLSA 8
           GLGSLS+
Sbjct: 730 GLGSLSS 736
>XP_005266228
          Length = 1085

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GLGSLSA 8
           GLGSLS+
Sbjct: 731 GLGSLSS 737
>NP_659477
          Length = 261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  SGLGSLS 7
          SGLG+LS
Sbjct: 62 SGLGALS 68
>NP_004487
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SGLGSLSA 8
          SGLGS+++
Sbjct: 36 SGLGSMNS 43
>NP_001273331
          Length = 1131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SGLGSL 6
           SGLGSL
Sbjct: 872 SGLGSL 877
>NP_000237
          Length = 1130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SGLGSL 6
           SGLGSL
Sbjct: 871 SGLGSL 876
>NP_056093
          Length = 1247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLGSLS 7
           GLGSLS
Sbjct: 396 GLGSLS 401
>NP_001243793
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLGSLSAA 9
           G+GS SAA
Sbjct: 706 GMGSKSAA 713
>NP_001243794
          Length = 900

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLGSLSAA 9
           G+GS SAA
Sbjct: 636 GMGSKSAA 643
>NP_001980
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLGSLSAA 9
           GLG+ SAA
Sbjct: 286 GLGAASAA 293
>NP_055602
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLGSLSAA 9
           G+GS SAA
Sbjct: 649 GMGSKSAA 656
>NP_001244286
          Length = 1021

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GLGSLSA 8
           GLG LSA
Sbjct: 658 GLGELSA 664
>NP_001078846
          Length = 1019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLGSLSAA 9
           + LG+LSAA
Sbjct: 136 NSLGALSAA 144
>NP_002494
          Length = 356

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SGLGSL 6
          SGLGSL
Sbjct: 19 SGLGSL 24
>NP_005512
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLGSLSAA 9
           G G+LSAA
Sbjct: 122 GAGALSAA 129
>NP_001073927
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SGLGSL 6
           SGLGSL
Sbjct: 160 SGLGSL 165
>NP_079452
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLGSLSA 8
           SGLG+L A
Sbjct: 746 SGLGALPA 753
>NP_001182446
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLGSLSAA 9
           G G+LSAA
Sbjct: 122 GAGALSAA 129
>NP_005193
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GLGSLSA 8
           GLG LSA
Sbjct: 565 GLGELSA 571
>XP_006723617
          Length = 762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLGSLSA 8
           SGLG+L A
Sbjct: 126 SGLGALPA 133
>XP_005260737
          Length = 1015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLGSLSA 8
           SGLG+L A
Sbjct: 379 SGLGALPA 386
>XP_006723616
          Length = 1223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLGSLSA 8
           SGLG+L A
Sbjct: 587 SGLGALPA 594
>XP_006723615
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLGSLSA 8
           SGLG+L A
Sbjct: 746 SGLGALPA 753
>XP_005260735
          Length = 1398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGLGSLSA 8
           SGLG+L A
Sbjct: 762 SGLGALPA 769
>XP_006720946
          Length = 1081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SGLGSL 6
           SGLGSL
Sbjct: 822 SGLGSL 827
>XP_005255380
          Length = 1082

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SGLGSL 6
           SGLGSL
Sbjct: 823 SGLGSL 828
>XP_006720945
          Length = 1096

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SGLGSL 6
           SGLGSL
Sbjct: 837 SGLGSL 842
>XP_006720944
          Length = 1097

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SGLGSL 6
           SGLGSL
Sbjct: 838 SGLGSL 843
>XP_005255378
          Length = 1145

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SGLGSL 6
           SGLGSL
Sbjct: 886 SGLGSL 891
>XP_005255377
          Length = 1146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SGLGSL 6
           SGLGSL
Sbjct: 887 SGLGSL 892
>XP_006720943
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SGLGSL 6
           SGLGSL
Sbjct: 949 SGLGSL 954
>XP_005249697
          Length = 225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLGSLSAA 9
           GLG+ SAA
Sbjct: 104 GLGAASAA 111
>XP_005249696
          Length = 225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GLGSLSAA 9
           GLG+ SAA
Sbjct: 104 GLGAASAA 111
>XP_005266932
          Length = 1008

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLGSLS 7
           GLGSLS
Sbjct: 157 GLGSLS 162
>XP_006715469
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLGSLS 7
           GLGSLS
Sbjct: 384 GLGSLS 389
>XP_005266931
          Length = 1283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLGSLS 7
           GLGSLS
Sbjct: 432 GLGSLS 437
>XP_006714680
          Length = 1002

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLGSLSAA 9
           + LG+LSAA
Sbjct: 97  NSLGALSAA 105
>XP_005270536
          Length = 638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GLGSLSA 8
           GLG LSA
Sbjct: 500 GLGELSA 506
>XP_005270535
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GLGSLSA 8
           GLG LSA
Sbjct: 565 GLGELSA 571
>XP_005270534
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GLGSLSA 8
           GLG LSA
Sbjct: 642 GLGELSA 648
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.297    0.115    0.280 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 464,579
Number of extensions: 728
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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