Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_065798                                                              17    3301
XP_005272097                                                           17    3301
XP_005272096                                                           17    3301
XP_006714725                                                           17    3301
XP_005272095                                                           17    3301
XP_005272094                                                           17    3301
NP_937762                                                              16    5631
NP_056141                                                              16    5631
NP_001164108                                                           16    5631
NP_000487                                                              16    5631
NP_001121190                                                           16    5631
NP_000218                                                              16    5631
NP_001121189                                                           16    5631
NP_001093259                                                           16    5631
NP_001093258                                                           16    5631
NP_001093257                                                           16    5631
NP_000864                                                              16    5631
XP_006724204                                                           16    5631
XP_005277570                                                           16    5631
XP_005277569                                                           16    5631
XP_006711309                                                           16    5631
XP_005277568                                                           16    5631
XP_005277567                                                           16    5631
NP_001093256                                                           16    5631
NP_000123                                                              16    7355
NP_110421                                                              16    7355
NP_001139542                                                           16    7355
NP_001139543                                                           16    7355
NP_001243299                                                           16    7355
NP_002139                                                              16    7355
NP_060615                                                              16    7355
XP_005254588                                                           16    7355
XP_005266617                                                           16    7355
XP_005266615                                                           16    7355
XP_005266614                                                           16    7355
XP_005266613                                                           16    7355
NP_001116244                                                           15    9605
NP_001191802                                                           15    9605
NP_001191801                                                           15    9605
NP_009077                                                              15    9605
NP_078939                                                              15    9605
XP_005257701                                                           15    9605
XP_005257700                                                           15    9605
XP_005268682                                                           15    9605



>NP_065798
          Length = 1512

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SGKSQSLNN 9
           SGK + LNN
Sbjct: 660 SGKKKGLNN 668






 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SGKSQSLNN 9
            +GKSQ L+N
Sbjct: 1180 TGKSQLLSN 1188





>XP_005272097
          Length = 1224

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SGKSQSLNN 9
           SGK + LNN
Sbjct: 372 SGKKKGLNN 380






 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGKSQSLNN 9
           +GKSQ L+N
Sbjct: 892 TGKSQLLSN 900





>XP_005272096
          Length = 1511

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SGKSQSLNN 9
           SGK + LNN
Sbjct: 660 SGKKKGLNN 668






 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SGKSQSLNN 9
            +GKSQ L+N
Sbjct: 1180 TGKSQLLSN 1188





>XP_006714725
          Length = 1512

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SGKSQSLNN 9
           SGK + LNN
Sbjct: 660 SGKKKGLNN 668






 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SGKSQSLNN 9
            +GKSQ L+N
Sbjct: 1180 TGKSQLLSN 1188





>XP_005272095
          Length = 1512

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SGKSQSLNN 9
           SGK + LNN
Sbjct: 660 SGKKKGLNN 668






 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SGKSQSLNN 9
            +GKSQ L+N
Sbjct: 1180 TGKSQLLSN 1188





>XP_005272094
          Length = 1512

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SGKSQSLNN 9
           SGK + LNN
Sbjct: 660 SGKKKGLNN 668






 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SGKSQSLNN 9
            +GKSQ L+N
Sbjct: 1180 TGKSQLLSN 1188





>NP_937762
          Length = 3333

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SGKSQSLNN 9
            S K+Q+LNN
Sbjct: 1913 SRKAQTLNN 1921





>NP_056141
          Length = 1071

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGKSQSLNN 9
           +G+S+S NN
Sbjct: 925 AGRSKSFNN 933





>NP_001164108
          Length = 1070

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGKSQSLNN 9
           +G+S+S NN
Sbjct: 924 AGRSKSFNN 932





>NP_000487
          Length = 205

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SGKSQSLN 8
          +GK QSLN
Sbjct: 9  AGKPQSLN 16





>NP_001121190
          Length = 1668

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGKSQSLNN 9
           S K+Q+LNN
Sbjct: 304 SRKAQTLNN 312





>NP_000218
          Length = 1724

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGKSQSLNN 9
           S K+Q+LNN
Sbjct: 304 SRKAQTLNN 312





>NP_001121189
          Length = 3277

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SGKSQSLNN 9
            S K+Q+LNN
Sbjct: 1913 SRKAQTLNN 1921





>NP_001093259
          Length = 275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGKSQSLNN 9
           SGK +S+N+
Sbjct: 96  SGKQESMNS 104





>NP_001093258
          Length = 275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGKSQSLNN 9
           SGK +S+N+
Sbjct: 96  SGKQESMNS 104





>NP_001093257
          Length = 275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGKSQSLNN 9
           SGK +S+N+
Sbjct: 96  SGKQESMNS 104





>NP_000864
          Length = 275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGKSQSLNN 9
           SGK +S+N+
Sbjct: 96  SGKQESMNS 104





>XP_006724204
          Length = 205

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SGKSQSLN 8
          +GK QSLN
Sbjct: 9  AGKPQSLN 16





>XP_005277570
          Length = 918

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGKSQSLNN 9
           +G+S+S NN
Sbjct: 772 AGRSKSFNN 780





>XP_005277569
          Length = 918

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGKSQSLNN 9
           +G+S+S NN
Sbjct: 772 AGRSKSFNN 780





>XP_006711309
          Length = 973

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGKSQSLNN 9
           +G+S+S NN
Sbjct: 925 AGRSKSFNN 933





>XP_005277568
          Length = 1070

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGKSQSLNN 9
           +G+S+S NN
Sbjct: 924 AGRSKSFNN 932





>XP_005277567
          Length = 1071

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGKSQSLNN 9
           +G+S+S NN
Sbjct: 925 AGRSKSFNN 933





>NP_001093256
          Length = 275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGKSQSLNN 9
           SGK +S+N+
Sbjct: 96  SGKQESMNS 104





>NP_000123
          Length = 2351

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGKSQSLNN 9
           S KSQ LNN
Sbjct: 425 SYKSQYLNN 433





>NP_110421
          Length = 651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KSQSLNN 9
           KSQ++NN
Sbjct: 457 KSQTINN 463





>NP_001139542
          Length = 744

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KSQSLNN 9
           KSQ++NN
Sbjct: 550 KSQTINN 556





>NP_001139543
          Length = 651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KSQSLNN 9
           KSQ++NN
Sbjct: 457 KSQTINN 463





>NP_001243299
          Length = 441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GKSQSLNN 9
          G+S +LNN
Sbjct: 13 GRSSTLNN 20





>NP_002139
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SGKSQSLNN 9
           +GK+Q  NN
Sbjct: 160 TGKTQEYNN 168





>NP_060615
          Length = 470

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GKSQSLNN 9
          G+SQSL N
Sbjct: 42 GRSQSLPN 49





>XP_005254588
          Length = 470

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GKSQSLNN 9
          G+SQSL N
Sbjct: 42 GRSQSLPN 49





>XP_005266617
          Length = 716

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KSQSLNN 9
           KSQ++NN
Sbjct: 457 KSQTINN 463





>XP_005266615
          Length = 744

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KSQSLNN 9
           KSQ++NN
Sbjct: 550 KSQTINN 556





>XP_005266614
          Length = 808

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KSQSLNN 9
           KSQ++NN
Sbjct: 550 KSQTINN 556





>XP_005266613
          Length = 809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KSQSLNN 9
           KSQ++NN
Sbjct: 550 KSQTINN 556





>NP_001116244
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GKSQSLNN 9
           GKS++L+N
Sbjct: 271 GKSKTLDN 278





>NP_001191802
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SGKSQSLNN 9
           SGK+  +NN
Sbjct: 284 SGKTVEINN 292





>NP_001191801
          Length = 495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SGKSQSLNN 9
           SGK+  +NN
Sbjct: 304 SGKTVEINN 312





>NP_009077
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GKSQSLN 8
           G+SQS+N
Sbjct: 309 GQSQSIN 315





>NP_078939
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SGKSQSLNN 9
           SGK+  +NN
Sbjct: 332 SGKTVEINN 340





>XP_005257701
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GKSQSLN 8
           G+SQS+N
Sbjct: 306 GQSQSIN 312





>XP_005257700
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GKSQSLN 8
           G+SQS+N
Sbjct: 315 GQSQSIN 321





>XP_005268682
          Length = 1172

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GKSQSLNN 9
           GKS++L+N
Sbjct: 271 GKSKTLDN 278





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.280    0.101    0.239 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 509,141
Number of extensions: 879
Number of successful extensions: 50
Number of sequences better than 10000.0: 44
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.6 bits)
S2: 28 (15.4 bits)

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