Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_073713                                                              21     175
NP_056147                                                              17    3301
NP_060236                                                              17    4312
NP_001073312                                                           17    4312
XP_006710775                                                           17    4312
XP_005263536                                                           17    4312
NP_835488                                                              16    5631
NP_073753                                                              16    5631
XP_005270412                                                           16    5631
XP_006710350                                                           16    5631
NP_009101                                                              16    5631
NP_689957                                                              16    7355
NP_055186                                                              16    7355
NP_001278407                                                           16    7355
NP_055873                                                              16    7355
NP_001009814                                                           16    7355
NP_001019849                                                           16    7355
XP_005259911                                                           16    7355
XP_006719855                                                           16    7355
XP_006719854                                                           16    7355
XP_006719853                                                           16    7355
NP_079162                                                              16    7355
NP_001277144                                                           15    9605
NP_001277143                                                           15    9605
NP_001243210                                                           15    9605
NP_001319                                                              15    9605
NP_001012632                                                           15    9605
NP_284941                                                              15    9605
NP_976046                                                              15    9605
NP_981967                                                              15    9605
NP_001077383                                                           15    9605
NP_001320                                                              15    9605
NP_061728                                                              15    9605
NP_060600                                                              15    9605
NP_008932                                                              15    9605
NP_001273919                                                           15    9605
NP_113683                                                              15    9605
XP_005269629                                                           15    9605
XP_005269628                                                           15    9605
XP_005269627                                                           15    9605
XP_005269626                                                           15    9605
XP_006717706                                                           15    9605
XP_005269625                                                           15    9605
XP_005269624                                                           15    9605
XP_006717705                                                           15    9605
XP_005269622                                                           15    9605
XP_005269621                                                           15    9605
XP_006717704                                                           15    9605
XP_005269619                                                           15    9605
XP_005269618                                                           15    9605
XP_006717002                                                           15    9605
XP_005251733                                                           15    9605
XP_005251732                                                           15    9605
XP_005251731                                                           15    9605
XP_005251730                                                           15    9605
XP_005272320                                                           15    9605
XP_005272319                                                           15    9605
XP_005272318                                                           15    9605
XP_005247653                                                           15    9605
XP_005247652                                                           15    9605
NP_689506                                                              15    9605
NP_113684                                                              15    9605
>NP_073713
          Length = 985

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SGAARIPKE 9
           SGAAR+PKE
Sbjct: 115 SGAARVPKE 123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 713 SGAARIRGE 721
>NP_056147
          Length = 361

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGAARIPKE 9
           +GAA +P+E
Sbjct: 156 AGAAEVPRE 164
>NP_060236
          Length = 1166

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SGAARIPK 8
          SGAAR P+
Sbjct: 71 SGAARAPR 78
>NP_001073312
          Length = 1759

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SGAARIPK 8
          SGAAR P+
Sbjct: 71 SGAARAPR 78
>XP_006710775
          Length = 1759

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SGAARIPK 8
          SGAAR P+
Sbjct: 71 SGAARAPR 78
>XP_005263536
          Length = 1783

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SGAARIPK 8
           SGAAR P+
Sbjct: 95  SGAARAPR 102
>NP_835488
          Length = 343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  GAARIPK 8
          GAAR+P+
Sbjct: 19 GAARLPR 25
>NP_073753
          Length = 836

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  GAARIPK 8
          GAAR+P+
Sbjct: 19 GAARLPR 25
>XP_005270412
          Length = 522

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GAARIPK 8
           GAAR PK
Sbjct: 343 GAARTPK 349
>XP_006710350
          Length = 571

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GAARIPK 8
           GAAR PK
Sbjct: 392 GAARTPK 398
>NP_009101
          Length = 571

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GAARIPK 8
           GAAR PK
Sbjct: 392 GAARTPK 398
>NP_689957
          Length = 2213

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SGAARIPK 8
           SG+ RIP+
Sbjct: 522 SGSVRIPR 529
>NP_055186
          Length = 646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SGAARIP 7
           SGA+R+P
Sbjct: 213 SGASRLP 219
>NP_001278407
          Length = 585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SGAARIP 7
           SGA+R+P
Sbjct: 152 SGASRLP 158
>NP_055873
          Length = 1905

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGAARIPKE 9
           SG++ +PKE
Sbjct: 367 SGSSLLPKE 375
>NP_001009814
          Length = 1039

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGAARIPKE 9
           SG++ +PKE
Sbjct: 367 SGSSLLPKE 375
>NP_001019849
          Length = 513

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GAARIP 7
           GAAR+P
Sbjct: 352 GAARVP 357
>XP_005259911
          Length = 612

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SGAARIP 7
           SGA+R+P
Sbjct: 179 SGASRLP 185
>XP_006719855
          Length = 1046

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGAARIPKE 9
           SG++ +PKE
Sbjct: 367 SGSSLLPKE 375
>XP_006719854
          Length = 1550

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SGAARIPKE 9
          SG++ +PKE
Sbjct: 12 SGSSLLPKE 20
>XP_006719853
          Length = 1809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SGAARIPKE 9
           SG++ +PKE
Sbjct: 271 SGSSLLPKE 279
>NP_079162
          Length = 257

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SGAARIPK 8
          SG+ R+PK
Sbjct: 16 SGSRRLPK 23
>NP_001277144
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>NP_001277143
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>NP_001243210
          Length = 198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAARIPKE 9
           GAA +P+E
Sbjct: 162 GAAPVPEE 169
>NP_001319
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 167 SGAARIRGE 175
>NP_001012632
          Length = 429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 156 SGAARIRGE 164
>NP_284941
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ARIPKE 9
           AR+PKE
Sbjct: 696 ARLPKE 701
>NP_976046
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SGAARIPKE 9
          +GAA +P E
Sbjct: 66 AGAASLPSE 74
>NP_981967
          Length = 238

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SGAARIPK 8
           +GA+R+P+
Sbjct: 159 AGASRVPQ 166
>NP_001077383
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>NP_001320
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>NP_061728
          Length = 948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SGAARIP 7
           +G+ARIP
Sbjct: 615 TGSARIP 621
>NP_060600
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAARIPKE 9
           GA+ IP+E
Sbjct: 111 GASEIPEE 118
>NP_008932
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  GAARIP 7
          GAAR+P
Sbjct: 17 GAARLP 22
>NP_001273919
          Length = 249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  GAARIP 7
          GAAR+P
Sbjct: 17 GAARLP 22
>NP_113683
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SGAARIP 7
           +G+ARIP
Sbjct: 615 TGSARIP 621
>XP_005269629
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>XP_005269628
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>XP_005269627
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>XP_005269626
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>XP_006717706
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>XP_005269625
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>XP_005269624
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>XP_006717705
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>XP_005269622
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>XP_005269621
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>XP_006717704
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>XP_005269619
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>XP_005269618
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 173 SGAARIRGE 181
>XP_006717002
          Length = 202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  GAARIP 7
          GAAR+P
Sbjct: 17 GAARLP 22
>XP_005251733
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  GAARIP 7
          GAAR+P
Sbjct: 17 GAARLP 22
>XP_005251732
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  GAARIP 7
          GAAR+P
Sbjct: 17 GAARLP 22
>XP_005251731
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  GAARIP 7
          GAAR+P
Sbjct: 17 GAARLP 22
>XP_005251730
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  GAARIP 7
          GAAR+P
Sbjct: 17 GAARLP 22
>XP_005272320
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 156 SGAARIRGE 164
>XP_005272319
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 156 SGAARIRGE 164
>XP_005272318
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SGAARIPKE 9
           SGAARI  E
Sbjct: 167 SGAARIRGE 175
>XP_005247653
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ARIPKE 9
           AR+PKE
Sbjct: 696 ARLPKE 701
>XP_005247652
          Length = 769

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ARIPKE 9
           AR+PKE
Sbjct: 724 ARLPKE 729
>NP_689506
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAARIPKE 9
           GA+R P+E
Sbjct: 98  GASRTPQE 105
>NP_113684
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SGAARIP 7
           +G+ARIP
Sbjct: 615 TGSARIP 621
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.124    0.331 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 651,422
Number of extensions: 1302
Number of successful extensions: 63
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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