Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     665
NP_001185763                                                           19     665
NP_055459                                                              19     665
XP_006711719                                                           19     665
XP_006711718                                                           19     665
XP_006711717                                                           19     665
XP_006711716                                                           19     665
XP_006711715                                                           19     665
XP_006711714                                                           19     665
XP_006711713                                                           19     665
XP_006711712                                                           19     665
XP_006711711                                                           19     665
XP_006711710                                                           19     665
XP_006711709                                                           19     665
XP_005277503                                                           19     665
XP_005273038                                                           19     665
XP_006711708                                                           19     665
XP_005277500                                                           19     665
XP_006711707                                                           19     665
XP_005277499                                                           19     665
XP_006711706                                                           19     665
XP_006711705                                                           19     665
XP_006710143                                                           19     665
XP_006710142                                                           19     665
XP_006710141                                                           19     665
NP_872357                                                              18    1935
XP_006726410                                                           18    1935
XP_005264301                                                           18    1935
XP_006711164                                                           18    1935
NP_006559                                                              17    3301
NP_065923                                                              16    5631
XP_005264815                                                           16    5631
XP_005264814                                                           16    5631
NP_055068                                                              16    7355
NP_001156750                                                           16    7355
NP_001156751                                                           16    7355
NP_001276332                                                           16    7355
NP_001276333                                                           16    7355
NP_001276334                                                           16    7355
NP_071757                                                              16    7355
XP_006724788                                                           16    7355
XP_006718008                                                           16    7355
XP_005270098                                                           16    7355
XP_005270092                                                           16    7355
XP_006718007                                                           16    7355
XP_005263433                                                           16    7355
NP_780775                                                              15    9605
NP_001230199                                                           15    9605
NP_037407                                                              15    9605
NP_055176                                                              15    9605
NP_001243112                                                           15    9605
NP_001243111                                                           15    9605
NP_085152                                                              15    9605
NP_079382                                                              15    9605
NP_001230200                                                           15    9605
XP_006722374                                                           15    9605
XP_006722373                                                           15    9605
XP_006722370                                                           15    9605
XP_006722365                                                           15    9605
XP_006721247                                                           15    9605
XP_006721246                                                           15    9605
XP_006721245                                                           15    9605
XP_006721244                                                           15    9605
XP_005271769                                                           15    9605
XP_006712502                                                           15    9605
XP_005244773                                                           15    9605
XP_005244772                                                           15    9605
XP_005244771                                                           15    9605
XP_006710392                                                           15    9605
NP_116262                                                              15    9605
NP_001254479                                                           15    9605
NP_597681                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1215 SLVKQDSKQ 1223
>NP_001185763
          Length = 2362

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1259 SLVKQDSKQ 1267
>NP_055459
          Length = 2346

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1259 SLVKQDSKQ 1267
>XP_006711719
          Length = 2302

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1215 SLVKQDSKQ 1223
>XP_006711718
          Length = 1436

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SFVKQDSKQ 9
           S VKQDSKQ
Sbjct: 266 SLVKQDSKQ 274
>XP_006711717
          Length = 2385

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1215 SLVKQDSKQ 1223
>XP_006711716
          Length = 2411

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1324 SLVKQDSKQ 1332
>XP_006711715
          Length = 2428

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1258 SLVKQDSKQ 1266
>XP_006711714
          Length = 2429

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1259 SLVKQDSKQ 1267
>XP_006711713
          Length = 2432

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1262 SLVKQDSKQ 1270
>XP_006711712
          Length = 2473

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1422 SLVKQDSKQ 1430
>XP_006711711
          Length = 2482

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1312 SLVKQDSKQ 1320
>XP_006711710
          Length = 2494

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1324 SLVKQDSKQ 1332
>XP_006711709
          Length = 2495

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1325 SLVKQDSKQ 1333
>XP_005277503
          Length = 2498

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1422 SLVKQDSKQ 1430
>XP_005273038
          Length = 2509

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1422 SLVKQDSKQ 1430
>XP_006711708
          Length = 2512

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1422 SLVKQDSKQ 1430
>XP_005277500
          Length = 2525

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1422 SLVKQDSKQ 1430
>XP_006711707
          Length = 2553

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1422 SLVKQDSKQ 1430
>XP_005277499
          Length = 2561

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1422 SLVKQDSKQ 1430
>XP_006711706
          Length = 2591

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1421 SLVKQDSKQ 1429
>XP_006711705
          Length = 2592

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDSKQ
Sbjct: 1422 SLVKQDSKQ 1430
>XP_006710143
          Length = 562

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SFVKQDSKQ 9
           S VKQDSKQ
Sbjct: 101 SLVKQDSKQ 109
>XP_006710142
          Length = 671

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SFVKQDSKQ 9
           S VKQDSKQ
Sbjct: 210 SLVKQDSKQ 218
>XP_006710141
          Length = 672

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SFVKQDSKQ 9
           S VKQDSKQ
Sbjct: 211 SLVKQDSKQ 219
>NP_872357
          Length = 414

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FVKQDSK 8
          F+KQDSK
Sbjct: 28 FIKQDSK 34
>XP_006726410
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDS+Q
Sbjct: 1062 SLVKQDSEQ 1070
>XP_005264301
          Length = 414

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FVKQDSK 8
          F+KQDSK
Sbjct: 28 FIKQDSK 34
>XP_006711164
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SFVKQDSKQ 9
            S VKQDS+Q
Sbjct: 1062 SLVKQDSEQ 1070
>NP_006559
          Length = 332

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   FVKQDSKQ 9
           F+K+DSK+
Sbjct: 141 FIKKDSKE 148
>NP_065923
          Length = 1028

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SFVKQDSKQ 9
           SFV++DS++
Sbjct: 164 SFVEEDSRR 172
>XP_005264815
          Length = 923

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SFVKQDSKQ 9
           SFV++DS++
Sbjct: 164 SFVEEDSRR 172
>XP_005264814
          Length = 1028

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SFVKQDSKQ 9
           SFV++DS++
Sbjct: 164 SFVEEDSRR 172
>NP_055068
          Length = 2725

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VKQDSK 8
           VKQDSK
Sbjct: 469 VKQDSK 474
>NP_001156750
          Length = 2732

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VKQDSK 8
           VKQDSK
Sbjct: 469 VKQDSK 474
>NP_001156751
          Length = 2731

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VKQDSK 8
           VKQDSK
Sbjct: 468 VKQDSK 473
>NP_001276332
          Length = 987

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SFVKQDSK 8
           SF+K+DS+
Sbjct: 450 SFLKEDSQ 457
>NP_001276333
          Length = 871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SFVKQDSK 8
           SF+K+DS+
Sbjct: 335 SFLKEDSQ 342
>NP_001276334
          Length = 1030

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SFVKQDSK 8
           SF+K+DS+
Sbjct: 493 SFLKEDSQ 500
>NP_071757
          Length = 1030

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SFVKQDSK 8
           SF+K+DS+
Sbjct: 493 SFLKEDSQ 500
>XP_006724788
          Length = 2570

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VKQDSK 8
           VKQDSK
Sbjct: 315 VKQDSK 320
>XP_006718008
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SFVKQDSK 8
           SF+K+DS+
Sbjct: 129 SFLKEDSQ 136
>XP_005270098
          Length = 829

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SFVKQDSK 8
           SF+K+DS+
Sbjct: 292 SFLKEDSQ 299
>XP_005270092
          Length = 872

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SFVKQDSK 8
           SF+K+DS+
Sbjct: 335 SFLKEDSQ 342
>XP_006718007
          Length = 1050

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SFVKQDSK 8
           SF+K+DS+
Sbjct: 514 SFLKEDSQ 521
>XP_005263433
          Length = 2832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SFVKQDSKQ 9
            S  K+DSKQ
Sbjct: 1484 SAAKEDSKQ 1492
>NP_780775
          Length = 1026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SFVKQDSKQ 9
           SFV +DS++
Sbjct: 163 SFVAEDSRR 171
>NP_001230199
          Length = 1100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SFVKQDSKQ 9
           SFV +DS++
Sbjct: 237 SFVAEDSRR 245
>NP_037407
          Length = 2663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VKQDSKQ 9
           VK+DSK+
Sbjct: 881 VKEDSKE 887
>NP_055176
          Length = 1100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SFVKQDSKQ 9
           SFV +DS++
Sbjct: 237 SFVAEDSRR 245
>NP_001243112
          Length = 2663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VKQDSKQ 9
           VK+DSK+
Sbjct: 881 VKEDSKE 887
>NP_001243111
          Length = 2663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VKQDSKQ 9
           VK+DSK+
Sbjct: 881 VKEDSKE 887
>NP_085152
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SFVKQDSKQ 9
           SFVK+D ++
Sbjct: 109 SFVKEDVRK 117
>NP_079382
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  FVKQDSK 8
          FVK+D K
Sbjct: 66 FVKEDDK 72
>NP_001230200
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SFVKQDSKQ 9
           SFV +DS++
Sbjct: 237 SFVAEDSRR 245
>XP_006722374
          Length = 944

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VKQDSKQ 9
           +K+DSKQ
Sbjct: 743 LKEDSKQ 749
>XP_006722373
          Length = 948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VKQDSKQ 9
           +K+DSKQ
Sbjct: 747 LKEDSKQ 753
>XP_006722370
          Length = 956

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VKQDSKQ 9
           +K+DSKQ
Sbjct: 755 LKEDSKQ 761
>XP_006722365
          Length = 981

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VKQDSKQ 9
           +K+DSKQ
Sbjct: 780 LKEDSKQ 786
>XP_006721247
          Length = 2564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VKQDSKQ 9
           VK+DSK+
Sbjct: 782 VKEDSKE 788
>XP_006721246
          Length = 2620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VKQDSKQ 9
           VK+DSK+
Sbjct: 838 VKEDSKE 844
>XP_006721245
          Length = 2629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VKQDSKQ 9
           VK+DSK+
Sbjct: 847 VKEDSKE 853
>XP_006721244
          Length = 2629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VKQDSKQ 9
           VK+DSK+
Sbjct: 847 VKEDSKE 853
>XP_005271769
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FVKQDSKQ 9
           FVK+DS +
Sbjct: 204 FVKEDSAE 211
>XP_006712502
          Length = 588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SFVKQDS 7
           +F+KQDS
Sbjct: 103 NFLKQDS 109
>XP_005244773
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SFVKQDSKQ 9
          SFVK+D ++
Sbjct: 67 SFVKEDVRK 75
>XP_005244772
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SFVKQDSKQ 9
           SFVK+D ++
Sbjct: 109 SFVKEDVRK 117
>XP_005244771
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SFVKQDSKQ 9
           SFVK+D ++
Sbjct: 109 SFVKEDVRK 117
>XP_006710392
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SFVKQDSKQ 9
           SFVK+D ++
Sbjct: 109 SFVKEDVRK 117
>NP_116262
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FVKQDSKQ 9
           FVK+DS +
Sbjct: 176 FVKEDSAE 183
>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SFVKQDSK 8
            SF K++SK
Sbjct: 3585 SFTKEESK 3592
>NP_597681
          Length = 27118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SFVKQDSK 8
            SF K++SK
Sbjct: 3414 SFTKEESK 3421
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.115    0.279 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 535,497
Number of extensions: 811
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package