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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     665
NP_001075109                                                           19     665
NP_065820                                                              16    5631
NP_001001557                                                           16    7355
NP_085150                                                              16    7355
NP_001004477                                                           16    7355
NP_000247                                                              15    9605
NP_001263256                                                           15    9605
NP_001263255                                                           15    9605
NP_653186                                                              15    9605
NP_945185                                                              15    9605
NP_001136175                                                           15    9605
NP_001136176                                                           15    9605
NP_001364                                                              15    9605
NP_060289                                                              15    9605
NP_001273144                                                           15    9605
NP_116237                                                              15    9605
NP_659441                                                              15    9605
NP_115544                                                              15    9605
XP_006725181                                                           15    9605
XP_006725180                                                           15    9605
XP_006722987                                                           15    9605
XP_005254029                                                           15    9605
XP_006718494                                                           15    9605
XP_005273799                                                           15    9605
XP_006718493                                                           15    9605
XP_006718301                                                           15    9605
XP_006716362                                                           15    9605
XP_006716361                                                           15    9605
XP_006711798                                                           15    9605

>NP_008835
          Length = 4128

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVDRSLFT 9
            SFVDRSL T
Sbjct: 1818 SFVDRSLLT 1826



>NP_001075109
          Length = 4097

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SFVDRSLFT 9
            SFVDRSL T
Sbjct: 1818 SFVDRSLLT 1826



>NP_065820
          Length = 1388

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    VDRSLFT 9
            +DRSL+T
Sbjct: 1301 IDRSLYT 1307



>NP_001001557
          Length = 455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SFVDRSL 7
           SFVDR L
Sbjct: 129 SFVDRGL 135



>NP_085150
          Length = 941

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FVDRSLFT 9
           F D+SL+T
Sbjct: 594 FADQSLYT 601



>NP_001004477
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SFVDRSLFT 9
          ++VDRSL T
Sbjct: 65 TWVDRSLHT 73



>NP_000247
          Length = 1274

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DRSLFT 9
           DRS+FT
Sbjct: 732 DRSIFT 737



>NP_001263256
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DRSLFT 9
           DRS+FT
Sbjct: 123 DRSIFT 128



>NP_001263255
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DRSLFT 9
           DRS+FT
Sbjct: 123 DRSIFT 128



>NP_653186
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DRSLFT 9
           DRS+FT
Sbjct: 123 DRSIFT 128



>NP_945185
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VDRSLFT 9
          +DRS+FT
Sbjct: 92 LDRSVFT 98



>NP_001136175
          Length = 704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VDRSLFT 9
          +DRS+FT
Sbjct: 62 LDRSVFT 68



>NP_001136176
          Length = 704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  VDRSLFT 9
          +DRS+FT
Sbjct: 62 LDRSVFT 68



>NP_001364
          Length = 4515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    FVDRSLF 8
            F D+SLF
Sbjct: 2645 FTDKSLF 2651



>NP_060289
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SFVDRSL 7
           SFVD+S+
Sbjct: 311 SFVDKSM 317



>NP_001273144
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SFVDRSLF 8
          S+VD +LF
Sbjct: 56 SYVDETLF 63



>NP_116237
          Length = 269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SFVDRSLF 8
          S+VD +LF
Sbjct: 32 SYVDETLF 39



>NP_659441
          Length = 787

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FVDRSL 7
           F+DRSL
Sbjct: 156 FIDRSL 161



>NP_115544
          Length = 830

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DRSLFT 9
           DRS+FT
Sbjct: 333 DRSIFT 338



>XP_006725181
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FVDRSL 7
           F+DRSL
Sbjct: 156 FIDRSL 161



>XP_006725180
          Length = 774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FVDRSL 7
           F+DRSL
Sbjct: 156 FIDRSL 161



>XP_006722987
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   SFVDRS 6
           SF+DRS
Sbjct: 316 SFIDRS 321



>XP_005254029
          Length = 269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SFVDRSLF 8
          S+VD +LF
Sbjct: 32 SYVDETLF 39



>XP_006718494
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  DRSLFT 9
          DRS+FT
Sbjct: 88 DRSIFT 93



>XP_005273799
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DRSLFT 9
           DRS+FT
Sbjct: 123 DRSIFT 128



>XP_006718493
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DRSLFT 9
           DRS+FT
Sbjct: 123 DRSIFT 128



>XP_006718301
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DRSLFT 9
           DRS+FT
Sbjct: 726 DRSIFT 731



>XP_006716362
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FVDRSL 7
           F+DRSL
Sbjct: 156 FIDRSL 161



>XP_006716361
          Length = 774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FVDRSL 7
           F+DRSL
Sbjct: 156 FIDRSL 161



>XP_006711798
          Length = 4586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    FVDRSLF 8
            F D+SLF
Sbjct: 2651 FTDKSLF 2657



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.337    0.142    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 397,676
Number of extensions: 588
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)