Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              17    2528
XP_006716142                                                           17    2528
XP_005250088                                                           17    2528
XP_006716141                                                           17    2528
XP_005250085                                                           17    2528
XP_006716140                                                           17    2528
XP_005250084                                                           17    2528
XP_005250083                                                           17    2528
XP_005250082                                                           17    2528
NP_006134                                                              17    4312
NP_054808                                                              16    5631
NP_001008564                                                           16    5631
NP_001034806                                                           16    5631
XP_005266657                                                           16    5631
XP_005263298                                                           16    5631
XP_006714387                                                           16    5631
XP_006714386                                                           16    5631
XP_005263300                                                           16    5631
XP_006714385                                                           16    5631
XP_005263299                                                           16    5631
XP_006714384                                                           16    5631
XP_005263295                                                           16    5631
XP_006714383                                                           16    5631
XP_006714382                                                           16    5631
XP_006714381                                                           16    5631
NP_001002909                                                           16    7355
NP_061945                                                              16    7355
XP_006721846                                                           16    7355
XP_006721845                                                           16    7355
XP_006721844                                                           16    7355
XP_005248605                                                           16    7355
NP_002438                                                              15    9605
NP_001231866                                                           15    9605
NP_001139438                                                           15    9605
NP_078966                                                              15    9605
NP_079510                                                              15    9605
NP_001073312                                                           15    9605
NP_996744                                                              15    9605
NP_055665                                                              15    9605
NP_001028289                                                           15    9605
XP_005254804                                                           15    9605
XP_006720791                                                           15    9605
XP_005254803                                                           15    9605
XP_005254800                                                           15    9605
XP_005254799                                                           15    9605
XP_005254755                                                           15    9605
XP_006717618                                                           15    9605
XP_005269456                                                           15    9605
XP_006717617                                                           15    9605
XP_006717616                                                           15    9605
XP_006717615                                                           15    9605
XP_005269454                                                           15    9605
XP_005269453                                                           15    9605
XP_006717614                                                           15    9605
XP_006717613                                                           15    9605
XP_006717612                                                           15    9605
XP_005269452                                                           15    9605
XP_005269451                                                           15    9605
XP_006717611                                                           15    9605
XP_005269450                                                           15    9605
XP_005269449                                                           15    9605
XP_005269448                                                           15    9605
XP_005269447                                                           15    9605
XP_005269446                                                           15    9605
XP_005269445                                                           15    9605
XP_006713496                                                           15    9605
XP_005265227                                                           15    9605
XP_006710775                                                           15    9605
XP_005263536                                                           15    9605
NP_003913                                                              15    9605
>NP_733751
          Length = 4911

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SFSSSADKS 9
           SFSSSAD S
Sbjct: 769 SFSSSADIS 777
>XP_006716142
          Length = 4927

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SFSSSADKS 9
           SFSSSAD S
Sbjct: 770 SFSSSADIS 778
>XP_005250088
          Length = 4928

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SFSSSADKS 9
           SFSSSAD S
Sbjct: 770 SFSSSADIS 778
>XP_006716141
          Length = 4959

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SFSSSADKS 9
           SFSSSAD S
Sbjct: 770 SFSSSADIS 778
>XP_005250085
          Length = 4979

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SFSSSADKS 9
           SFSSSAD S
Sbjct: 770 SFSSSADIS 778
>XP_006716140
          Length = 4982

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SFSSSADKS 9
           SFSSSAD S
Sbjct: 770 SFSSSADIS 778
>XP_005250084
          Length = 4982

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SFSSSADKS 9
           SFSSSAD S
Sbjct: 770 SFSSSADIS 778
>XP_005250083
          Length = 4982

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SFSSSADKS 9
           SFSSSAD S
Sbjct: 769 SFSSSADIS 777
>XP_005250082
          Length = 4983

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SFSSSADKS 9
           SFSSSAD S
Sbjct: 770 SFSSSADIS 778
>NP_006134
          Length = 415

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SFSSSADK 8
           SFSSSA K
Sbjct: 319 SFSSSASK 326
>NP_054808
          Length = 599

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSSSADK 8
           FSSS+DK
Sbjct: 221 FSSSSDK 227
>NP_001008564
          Length = 587

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSSSADK 8
           FSSS+DK
Sbjct: 209 FSSSSDK 215
>NP_001034806
          Length = 414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSSSADK 8
           F+SSADK
Sbjct: 247 FTSSADK 253
>XP_005266657
          Length = 566

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSSSADK 8
           FSSS+DK
Sbjct: 221 FSSSSDK 227
>XP_005263298
          Length = 448

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSSSADK 8
           F+SSADK
Sbjct: 281 FTSSADK 287
>XP_006714387
          Length = 295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSSSADK 8
           F+SSADK
Sbjct: 112 FTSSADK 118
>XP_006714386
          Length = 295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSSSADK 8
           F+SSADK
Sbjct: 112 FTSSADK 118
>XP_005263300
          Length = 321

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSSSADK 8
           F+SSADK
Sbjct: 154 FTSSADK 160
>XP_006714385
          Length = 337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSSSADK 8
           F+SSADK
Sbjct: 154 FTSSADK 160
>XP_005263299
          Length = 337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSSSADK 8
           F+SSADK
Sbjct: 154 FTSSADK 160
>XP_006714384
          Length = 463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSSSADK 8
           F+SSADK
Sbjct: 296 FTSSADK 302
>XP_005263295
          Length = 464

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSSSADK 8
           F+SSADK
Sbjct: 281 FTSSADK 287
>XP_006714383
          Length = 479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSSSADK 8
           F+SSADK
Sbjct: 296 FTSSADK 302
>XP_006714382
          Length = 479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSSSADK 8
           F+SSADK
Sbjct: 296 FTSSADK 302
>XP_006714381
          Length = 479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSSSADK 8
           F+SSADK
Sbjct: 296 FTSSADK 302
>NP_001002909
          Length = 1502

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SFSSSADKS 9
           S+SSS+D S
Sbjct: 869 SYSSSSDAS 877
>NP_061945
          Length = 304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SFSSSADK 8
           SFSSSA++
Sbjct: 295 SFSSSAEE 302
>XP_006721846
          Length = 1424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SFSSSADKS 9
           S+SSS+D S
Sbjct: 791 SYSSSSDAS 799
>XP_006721845
          Length = 1424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SFSSSADKS 9
           S+SSS+D S
Sbjct: 791 SYSSSSDAS 799
>XP_006721844
          Length = 1424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SFSSSADKS 9
           S+SSS+D S
Sbjct: 791 SYSSSSDAS 799
>XP_005248605
          Length = 304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SFSSSADK 8
           SFSSSA++
Sbjct: 295 SFSSSAEE 302
>NP_002438
          Length = 1400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SFSSSADKS 9
            SFS S D+S
Sbjct: 1039 SFSDSEDES 1047
>NP_001231866
          Length = 1351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFS S D+S
Sbjct: 990 SFSDSEDES 998
>NP_001139438
          Length = 2896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 128 SFSSDPDES 136
>NP_078966
          Length = 14507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SFSSSADK 8
            +FSS++DK
Sbjct: 5096 NFSSTSDK 5103
>NP_079510
          Length = 305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSSADKS 9
           SSS+DKS
Sbjct: 249 SSSSDKS 255
>NP_001073312
          Length = 1759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FSSSAD 7
            FSSSAD
Sbjct: 1551 FSSSAD 1556
>NP_996744
          Length = 2948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 189 SFSSGIDQS 197
>NP_055665
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SSSADKS 9
            +SSADKS
Sbjct: 1090 NSSADKS 1096
>NP_001028289
          Length = 1075

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SSSADKS 9
            +SSADKS
Sbjct: 1066 NSSADKS 1072
>XP_005254804
          Length = 4796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           S  SSAD+S
Sbjct: 309 SLGSSADRS 317
>XP_006720791
          Length = 4853

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           S  SSAD+S
Sbjct: 309 SLGSSADRS 317
>XP_005254803
          Length = 4854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           S  SSAD+S
Sbjct: 309 SLGSSADRS 317
>XP_005254800
          Length = 4861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           S  SSAD+S
Sbjct: 309 SLGSSADRS 317
>XP_005254799
          Length = 4861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           S  SSAD+S
Sbjct: 309 SLGSSADRS 317
>XP_005254755
          Length = 305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSSADKS 9
           SSS+DKS
Sbjct: 249 SSSSDKS 255
>XP_006717618
          Length = 2826

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 189 SFSSGIDQS 197
>XP_005269456
          Length = 2846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_006717617
          Length = 2887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_006717616
          Length = 2891

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_006717615
          Length = 2903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_005269454
          Length = 2912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_005269453
          Length = 2922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_006717614
          Length = 2938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_006717613
          Length = 2948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 189 SFSSGIDQS 197
>XP_006717612
          Length = 2950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_005269452
          Length = 2954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_005269451
          Length = 2957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_006717611
          Length = 2964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_005269450
          Length = 2968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_005269449
          Length = 2969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_005269448
          Length = 2979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 189 SFSSGIDQS 197
>XP_005269447
          Length = 2980

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_005269446
          Length = 2999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_005269445
          Length = 2999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           SFSS  D+S
Sbjct: 209 SFSSGIDQS 217
>XP_006713496
          Length = 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSSADKS 9
           +SSADKS
Sbjct: 582 NSSADKS 588
>XP_005265227
          Length = 1401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SFSSSADKS 9
            SFS S D+S
Sbjct: 1040 SFSDSEDES 1048
>XP_006710775
          Length = 1759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FSSSAD 7
            FSSSAD
Sbjct: 1551 FSSSAD 1556
>XP_005263536
          Length = 1783

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FSSSAD 7
            FSSSAD
Sbjct: 1575 FSSSAD 1580
>NP_003913
          Length = 4861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFSSSADKS 9
           S  SSAD+S
Sbjct: 309 SLGSSADRS 317
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.280   0.0914    0.200 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 480,399
Number of extensions: 863
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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