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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              18    1482
NP_443161                                                              17    4312
NP_001276018                                                           17    4312
NP_079048                                                              17    4312
NP_001276019                                                           17    4312
NP_001276017                                                           17    4312
NP_001276020                                                           17    4312
XP_005271279                                                           17    4312
XP_005271277                                                           17    4312
XP_005271276                                                           17    4312
XP_005271275                                                           17    4312
XP_005271273                                                           17    4312
XP_006710380                                                           17    4312
XP_005245788                                                           17    4312
XP_006710379                                                           17    4312
XP_006710378                                                           17    4312
NP_954868                                                              16    5631
NP_954869                                                              16    5631
NP_001277153                                                           16    5631
NP_954870                                                              16    5631
NP_079039                                                              16    5631
NP_996897                                                              16    5631
NP_954863                                                              16    5631
XP_005271269                                                           16    5631
NP_001041631                                                           16    7355
NP_003026                                                              16    7355
NP_001269867                                                           16    7355
NP_001269868                                                           16    7355
NP_001269866                                                           16    7355
NP_001269865                                                           16    7355
XP_005259315                                                           16    7355
XP_005259314                                                           16    7355
XP_006710898                                                           16    7355
XP_006710897                                                           16    7355
NP_077297                                                              16    7355
NP_055616                                                              15    9605
XP_005273329                                                           15    9605

>NP_115803
          Length = 1156

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SFLDIKIIR 9
           SFLDIK IR
Sbjct: 199 SFLDIKRIR 207



>NP_443161
          Length = 1412

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SFLDIKIIR 9
            SFLD+K +R
Sbjct: 1179 SFLDLKNLR 1187



>NP_001276018
          Length = 1123

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FLDIKIIR 9
           FLD+ IIR
Sbjct: 730 FLDLSIIR 737



>NP_079048
          Length = 1142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FLDIKIIR 9
           FLD+ IIR
Sbjct: 749 FLDLSIIR 756



>NP_001276019
          Length = 1142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FLDIKIIR 9
           FLD+ IIR
Sbjct: 749 FLDLSIIR 756



>NP_001276017
          Length = 1142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FLDIKIIR 9
           FLD+ IIR
Sbjct: 749 FLDLSIIR 756



>NP_001276020
          Length = 782

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FLDIKIIR 9
           FLD+ IIR
Sbjct: 389 FLDLSIIR 396



>XP_005271279
          Length = 782

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FLDIKIIR 9
           FLD+ IIR
Sbjct: 389 FLDLSIIR 396



>XP_005271277
          Length = 951

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FLDIKIIR 9
           FLD+ IIR
Sbjct: 558 FLDLSIIR 565



>XP_005271276
          Length = 1067

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FLDIKIIR 9
           FLD+ IIR
Sbjct: 674 FLDLSIIR 681



>XP_005271275
          Length = 1067

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FLDIKIIR 9
           FLD+ IIR
Sbjct: 674 FLDLSIIR 681



>XP_005271273
          Length = 1130

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FLDIKIIR 9
           FLD+ IIR
Sbjct: 737 FLDLSIIR 744



>XP_006710380
          Length = 1398

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SFLDIKIIR 9
            SFLD+K +R
Sbjct: 1165 SFLDLKNLR 1173



>XP_005245788
          Length = 1434

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SFLDIKIIR 9
            SFLD+K +R
Sbjct: 1201 SFLDLKNLR 1209



>XP_006710379
          Length = 1452

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SFLDIKIIR 9
            SFLD+K +R
Sbjct: 1201 SFLDLKNLR 1209



>XP_006710378
          Length = 1478

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SFLDIKIIR 9
            SFLD+K +R
Sbjct: 1200 SFLDLKNLR 1208



>NP_954868
          Length = 533

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FLDIKIIR 9
           F DIK++R
Sbjct: 160 FFDIKLLR 167



>NP_954869
          Length = 513

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FLDIKIIR 9
           F DIK++R
Sbjct: 140 FFDIKLLR 147



>NP_001277153
          Length = 413

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  FLDIKIIR 9
          F DIK++R
Sbjct: 40 FFDIKLLR 47



>NP_954870
          Length = 551

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FLDIKIIR 9
           F DIK++R
Sbjct: 178 FFDIKLLR 185



>NP_079039
          Length = 848

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SFLDIKIIR 9
           SF D+++IR
Sbjct: 212 SFTDLQVIR 220



>NP_996897
          Length = 545

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SFLDIKIIR 9
           SF D+++IR
Sbjct: 212 SFTDLQVIR 220



>NP_954863
          Length = 522

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FLDIKIIR 9
           F DIK++R
Sbjct: 160 FFDIKLLR 167



>XP_005271269
          Length = 783

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SFLDIKIIR 9
           SF D+++IR
Sbjct: 212 SFTDLQVIR 220



>NP_001041631
          Length = 1288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SFLDIKIIR 9
            +FLD+K +R
Sbjct: 1274 TFLDVKRLR 1282



>NP_003026
          Length = 1287

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SFLDIKIIR 9
            +FLD+K +R
Sbjct: 1273 TFLDVKRLR 1281



>NP_001269867
          Length = 1241

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SFLDIKIIR 9
            +FLD+K +R
Sbjct: 1227 TFLDVKRLR 1235



>NP_001269868
          Length = 1223

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SFLDIKIIR 9
            +FLD+K +R
Sbjct: 1209 TFLDVKRLR 1217



>NP_001269866
          Length = 1270

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SFLDIKIIR 9
            +FLD+K +R
Sbjct: 1256 TFLDVKRLR 1264



>NP_001269865
          Length = 1287

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SFLDIKIIR 9
            +FLD+K +R
Sbjct: 1273 TFLDVKRLR 1281



>XP_005259315
          Length = 451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFLDIKIIR 9
           SFL  K+IR
Sbjct: 377 SFLKAKVIR 385



>XP_005259314
          Length = 473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFLDIKIIR 9
           SFL  K+IR
Sbjct: 399 SFLKAKVIR 407



>XP_006710898
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SFLDIKIIR 9
           +FLD+K +R
Sbjct: 828 TFLDVKRLR 836



>XP_006710897
          Length = 1288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SFLDIKIIR 9
            +FLD+K +R
Sbjct: 1274 TFLDVKRLR 1282



>NP_077297
          Length = 480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFLDIKIIR 9
           SFL  K+IR
Sbjct: 406 SFLKAKVIR 414



>NP_055616
          Length = 2137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SFLDIKIIR 9
            SFL  K+I+
Sbjct: 1768 SFLSFKVIK 1776



>XP_005273329
          Length = 1934

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SFLDIKIIR 9
            SFL  K+I+
Sbjct: 1565 SFLSFKVIK 1573



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.345    0.163    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 437,573
Number of extensions: 651
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)