Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           20     509
NP_036462                                                              20     509
NP_001243397                                                           20     509
XP_005269721                                                           20     509
NP_001092882                                                           18    1482
NP_006757                                                              18    1482
NP_001092883                                                           18    1482
XP_005273706                                                           18    1482
NP_055641                                                              15    9605
NP_003598                                                              15    9605
XP_006711900                                                           15    9605
XP_005273381                                                           15    9605
XP_005273380                                                           15    9605
XP_005273379                                                           15    9605
XP_006711899                                                           15    9605
XP_005273378                                                           15    9605
XP_005273377                                                           15    9605
XP_006711898                                                           15    9605
XP_006711897                                                           15    9605
XP_005273375                                                           15    9605
XP_005273374                                                           15    9605
>NP_001243398
          Length = 1781

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SETVQAIQS 9
            SETVQA+QS
Sbjct: 1247 SETVQAVQS 1255
>NP_036462
          Length = 2073

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SETVQAIQS 9
            SETVQA+QS
Sbjct: 1539 SETVQAVQS 1547
>NP_001243397
          Length = 1890

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SETVQAIQS 9
            SETVQA+QS
Sbjct: 1356 SETVQAVQS 1364
>XP_005269721
          Length = 2073

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SETVQAIQS 9
            SETVQA+QS
Sbjct: 1539 SETVQAVQS 1547
>NP_001092882
          Length = 2004

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    ETVQAIQS 9
            ETVQA+QS
Sbjct: 1423 ETVQAVQS 1430
>NP_006757
          Length = 2004

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    ETVQAIQS 9
            ETVQA+QS
Sbjct: 1423 ETVQAVQS 1430
>NP_001092883
          Length = 2004

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    ETVQAIQS 9
            ETVQA+QS
Sbjct: 1423 ETVQAVQS 1430
>XP_005273706
          Length = 1997

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    ETVQAIQS 9
            ETVQA+QS
Sbjct: 1416 ETVQAVQS 1423
>NP_055641
          Length = 1638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETVQAIQ 8
           ++TVQA+Q
Sbjct: 466 TQTVQALQ 473
>NP_003598
          Length = 1719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETVQAIQ 8
           ++TVQA+Q
Sbjct: 466 TQTVQALQ 473
>XP_006711900
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETVQAIQ 8
           ++TVQA+Q
Sbjct: 466 TQTVQALQ 473
>XP_005273381
          Length = 1732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETVQAIQ 8
           ++TVQA+Q
Sbjct: 466 TQTVQALQ 473
>XP_005273380
          Length = 1751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETVQAIQ 8
           ++TVQA+Q
Sbjct: 466 TQTVQALQ 473
>XP_005273379
          Length = 1754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETVQAIQ 8
           ++TVQA+Q
Sbjct: 466 TQTVQALQ 473
>XP_006711899
          Length = 1770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETVQAIQ 8
           ++TVQA+Q
Sbjct: 466 TQTVQALQ 473
>XP_005273378
          Length = 1781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETVQAIQ 8
           ++TVQA+Q
Sbjct: 466 TQTVQALQ 473
>XP_005273377
          Length = 1794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETVQAIQ 8
           ++TVQA+Q
Sbjct: 466 TQTVQALQ 473
>XP_006711898
          Length = 1797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETVQAIQ 8
           ++TVQA+Q
Sbjct: 466 TQTVQALQ 473
>XP_006711897
          Length = 1816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETVQAIQ 8
           ++TVQA+Q
Sbjct: 466 TQTVQALQ 473
>XP_005273375
          Length = 1829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETVQAIQ 8
           ++TVQA+Q
Sbjct: 466 TQTVQALQ 473
>XP_005273374
          Length = 1832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETVQAIQ 8
           ++TVQA+Q
Sbjct: 466 TQTVQALQ 473
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.289   0.0995    0.208 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 284,690
Number of extensions: 419
Number of successful extensions: 21
Number of sequences better than 10000.0: 21
Number of HSP's gapped: 21
Number of HSP's successfully gapped: 21
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package