Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              18    1135
XP_005266703                                                           18    1135
NP_006759                                                              17    2528
XP_005254001                                                           17    2528
NP_878918                                                              17    4312
NP_055995                                                              17    4312
XP_006720147                                                           17    4312
XP_005267517                                                           17    4312
XP_005267516                                                           17    4312
XP_005267515                                                           17    4312
XP_005267514                                                           17    4312
XP_005267513                                                           17    4312
XP_005267512                                                           17    4312
XP_005267511                                                           17    4312
NP_057121                                                              16    7355
NP_001633                                                              16    7355
NP_001269893                                                           16    7355
NP_001096645                                                           16    7355
NP_001230228                                                           16    7355
XP_005255192                                                           16    7355
XP_006720913                                                           16    7355
NP_001135748                                                           16    7355
NP_001135749                                                           16    7355
NP_001135750                                                           16    7355
NP_001259004                                                           15    9605
NP_001177718                                                           15    9605
NP_005144                                                              15    9605
NP_000424                                                              15    9605
NP_899236                                                              15    9605
NP_056363                                                              15    9605
NP_001138241                                                           15    9605
NP_001138242                                                           15    9605
NP_001275993                                                           15    9605
NP_000225                                                              15    9605
NP_001275992                                                           15    9605
NP_006337                                                              15    9605
NP_001008723                                                           15    9605
NP_001177723                                                           15    9605
NP_001157871                                                           15    9605
NP_001121123                                                           15    9605
XP_006723279                                                           15    9605
XP_005258991                                                           15    9605
XP_006723278                                                           15    9605
XP_005257998                                                           15    9605
XP_005257995                                                           15    9605
XP_005257994                                                           15    9605
XP_006721395                                                           15    9605
XP_006721393                                                           15    9605
XP_006719818                                                           15    9605
XP_005266286                                                           15    9605
XP_006715232                                                           15    9605
XP_005249382                                                           15    9605
XP_005249381                                                           15    9605
XP_005249380                                                           15    9605
XP_005249379                                                           15    9605
XP_005249377                                                           15    9605
XP_005249376                                                           15    9605
XP_005249375                                                           15    9605
XP_005249374                                                           15    9605
XP_005249373                                                           15    9605
XP_005249372                                                           15    9605
XP_005249371                                                           15    9605
XP_005249370                                                           15    9605
XP_005249369                                                           15    9605
XP_005249368                                                           15    9605
XP_005249367                                                           15    9605
XP_005245264                                                           15    9605
NP_001139669                                                           15    9605
NP_001273                                                              15    9605
NP_001025177                                                           15    9605
>NP_443179
          Length = 2170

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SETKQEVQQ 9
            SETKQ VQQ
Sbjct: 1131 SETKQGVQQ 1139
>XP_005266703
          Length = 1501

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SETKQEVQQ 9
           SETKQ VQQ
Sbjct: 462 SETKQGVQQ 470
>NP_006759
          Length = 592

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SETKQEVQQ 9
           +ET+QE+Q+
Sbjct: 551 AETRQEIQE 559
>XP_005254001
          Length = 633

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SETKQEVQQ 9
           +ET+QE+Q+
Sbjct: 592 AETRQEIQE 600
>NP_878918
          Length = 6907

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SETKQEVQQ 9
            SETK+ V+Q
Sbjct: 1865 SETKKSVEQ 1873
>NP_055995
          Length = 6885

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SETKQEVQQ 9
            SETK+ V+Q
Sbjct: 1865 SETKKSVEQ 1873
>XP_006720147
          Length = 4788

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SETKQEVQQ 9
            SETK+ V+Q
Sbjct: 1865 SETKKSVEQ 1873
>XP_005267517
          Length = 6883

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SETKQEVQQ 9
            SETK+ V+Q
Sbjct: 1865 SETKKSVEQ 1873
>XP_005267516
          Length = 6884

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SETKQEVQQ 9
            SETK+ V+Q
Sbjct: 1865 SETKKSVEQ 1873
>XP_005267515
          Length = 6899

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SETKQEVQQ 9
            SETK+ V+Q
Sbjct: 1865 SETKKSVEQ 1873
>XP_005267514
          Length = 6908

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SETKQEVQQ 9
            SETK+ V+Q
Sbjct: 1865 SETKKSVEQ 1873
>XP_005267513
          Length = 6921

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SETKQEVQQ 9
            SETK+ V+Q
Sbjct: 1865 SETKKSVEQ 1873
>XP_005267512
          Length = 6922

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SETKQEVQQ 9
            SETK+ V+Q
Sbjct: 1865 SETKKSVEQ 1873
>XP_005267511
          Length = 6922

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SETKQEVQQ 9
            SETK+ V+Q
Sbjct: 1865 SETKKSVEQ 1873
>NP_057121
          Length = 253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ETKQEVQQ 9
           +TK+EV+Q
Sbjct: 141 DTKKEVEQ 148
>NP_001633
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ETKQEVQQ 9
          ETK+EV Q
Sbjct: 82 ETKEEVLQ 89
>NP_001269893
          Length = 249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SETKQEV 7
           SETK+EV
Sbjct: 130 SETKKEV 136
>NP_001096645
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SETKQEVQQ 9
           S+T+QE+Q+
Sbjct: 168 SQTEQELQR 176
>NP_001230228
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ETKQEVQQ 9
          ETK+EV Q
Sbjct: 92 ETKEEVLQ 99
>XP_005255192
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SETKQEVQQ 9
           S+T+QE+Q+
Sbjct: 168 SQTEQELQR 176
>XP_006720913
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SETKQEVQQ 9
           S+T+QE+Q+
Sbjct: 168 SQTEQELQR 176
>NP_001135748
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ETKQEVQQ 9
          ETK+EV Q
Sbjct: 82 ETKEEVLQ 89
>NP_001135749
          Length = 695

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ETKQEVQQ 9
          ETK+EV Q
Sbjct: 82 ETKEEVLQ 89
>NP_001135750
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ETKQEVQQ 9
          ETK+EV Q
Sbjct: 82 ETKEEVLQ 89
>NP_001259004
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETKQEVQ 8
           ++TKQEV+
Sbjct: 665 TKTKQEVE 672
>NP_001177718
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ETKQEVQ 8
           ETK+E+Q
Sbjct: 173 ETKEELQ 179
>NP_005144
          Length = 798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETKQEVQ 8
           ++TKQEV+
Sbjct: 661 TKTKQEVE 668
>NP_000424
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ETKQEVQ 8
           ETK+E+Q
Sbjct: 254 ETKEELQ 260
>NP_899236
          Length = 5497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 2697 KQEIQQ 2702
>NP_056363
          Length = 5171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 2371 KQEIQQ 2376
>NP_001138241
          Length = 5675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 2875 KQEIQQ 2880
>NP_001138242
          Length = 5537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 2737 KQEIQQ 2742
>NP_001275993
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKQEVQQ 9
           TKQE+Q+
Sbjct: 139 TKQELQE 145
>NP_000225
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKQEVQQ 9
           TKQE+Q+
Sbjct: 207 TKQELQE 213
>NP_001275992
          Length = 888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKQEVQQ 9
           TKQE+Q+
Sbjct: 176 TKQELQE 182
>NP_006337
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SETKQEVQQ 9
           ++TKQ +QQ
Sbjct: 248 ADTKQLIQQ 256
>NP_001008723
          Length = 872

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SETKQEVQQ 9
           S+ +QE+QQ
Sbjct: 198 SQFQQEIQQ 206
>NP_001177723
          Length = 481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ETKQEVQ 8
           ETK+E+Q
Sbjct: 209 ETKEELQ 215
>NP_001157871
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ETKQEVQQ 9
           + KQE+QQ
Sbjct: 616 DVKQELQQ 623
>NP_001121123
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ETKQEVQ 8
           ETK+E+Q
Sbjct: 254 ETKEELQ 260
>XP_006723279
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKQEVQQ 9
           TKQE+Q+
Sbjct: 207 TKQELQE 213
>XP_005258991
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKQEVQQ 9
           TKQE+Q+
Sbjct: 177 TKQELQE 183
>XP_006723278
          Length = 918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKQEVQQ 9
           TKQE+Q+
Sbjct: 206 TKQELQE 212
>XP_005257998
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SETKQEVQQ 9
           SET++ VQQ
Sbjct: 497 SETQELVQQ 505
>XP_005257995
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SETKQEVQQ 9
           SET++ VQQ
Sbjct: 497 SETQELVQQ 505
>XP_005257994
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SETKQEVQQ 9
           SET++ VQQ
Sbjct: 497 SETQELVQQ 505
>XP_006721395
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETKQEVQ 8
           ++TKQEV+
Sbjct: 465 TKTKQEVE 472
>XP_006721393
          Length = 781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SETKQEVQ 8
           ++TKQEV+
Sbjct: 666 TKTKQEVE 673
>XP_006719818
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SETKQEVQQ 9
           ++TKQ +QQ
Sbjct: 248 ADTKQLIQQ 256
>XP_005266286
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SETKQEVQQ 9
           ++TKQ +QQ
Sbjct: 248 ADTKQLIQQ 256
>XP_006715232
          Length = 7498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 4783 KQEIQQ 4788
>XP_005249382
          Length = 5732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 2908 KQEIQQ 2913
>XP_005249381
          Length = 7281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 4457 KQEIQQ 4462
>XP_005249380
          Length = 7607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 4783 KQEIQQ 4788
>XP_005249379
          Length = 7633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 4809 KQEIQQ 4814
>XP_005249377
          Length = 7640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 4816 KQEIQQ 4821
>XP_005249376
          Length = 7647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 4823 KQEIQQ 4828
>XP_005249375
          Length = 7680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 4856 KQEIQQ 4861
>XP_005249374
          Length = 7709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 4994 KQEIQQ 4999
>XP_005249373
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 4899 KQEIQQ 4904
>XP_005249372
          Length = 7785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 4961 KQEIQQ 4966
>XP_005249371
          Length = 7788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 4994 KQEIQQ 4999
>XP_005249370
          Length = 7794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 4994 KQEIQQ 4999
>XP_005249369
          Length = 7797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 4973 KQEIQQ 4978
>XP_005249368
          Length = 7812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 4994 KQEIQQ 4999
>XP_005249367
          Length = 7818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    KQEVQQ 9
            KQE+QQ
Sbjct: 4994 KQEIQQ 4999
>XP_005245264
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ETKQEVQ 8
           ETK+E+Q
Sbjct: 218 ETKEELQ 224
>NP_001139669
          Length = 7081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SETKQEVQQ 9
            +E K+EVQ+
Sbjct: 2248 TEEKEEVQE 2256
>NP_001273
          Length = 937

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SETKQEVQQ 9
           SET++ VQQ
Sbjct: 497 SETQELVQQ 505
>NP_001025177
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SETKQEVQQ 9
           SET++ VQQ
Sbjct: 497 SETQELVQQ 505
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.276   0.0946    0.201 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 530,994
Number of extensions: 1331
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.6 bits)
S2: 28 (15.4 bits)

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