Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006056                                                              18    1135
XP_005260701                                                           18    1135
XP_005260700                                                           18    1135
XP_005260698                                                           18    1135
XP_006710313                                                           18    1135
NP_001077379                                                           18    1135
NP_079133                                                              18    1482
NP_001248396                                                           17    2528
NP_115517                                                              17    2528
NP_001153441                                                           16    5631
NP_001972                                                              16    5631
NP_005550                                                              16    5631
NP_060613                                                              16    5631
XP_006710509                                                           16    5631
XP_005270675                                                           16    5631
NP_001231118                                                           16    7355
NP_001231121                                                           16    7355
NP_055564                                                              16    7355
NP_001231119                                                           16    7355
NP_001231120                                                           16    7355
NP_001231122                                                           16    7355
NP_001177935                                                           16    7355
NP_689830                                                              16    7355
NP_851825                                                              16    7355
NP_001229347                                                           16    7355
NP_001229346                                                           16    7355
NP_001229345                                                           16    7355
NP_653175                                                              16    7355
NP_851808                                                              16    7355
XP_005260474                                                           16    7355
XP_006720406                                                           16    7355
XP_006720405                                                           16    7355
XP_006720404                                                           16    7355
XP_006720403                                                           16    7355
XP_006720402                                                           16    7355
XP_006720401                                                           16    7355
XP_006720400                                                           16    7355
XP_006720399                                                           16    7355
XP_006720376                                                           16    7355
XP_006720375                                                           16    7355
XP_006720374                                                           16    7355
XP_006720373                                                           16    7355
XP_006720372                                                           16    7355
XP_006720371                                                           16    7355
XP_006720370                                                           16    7355
XP_006720369                                                           16    7355
XP_006710362                                                           16    7355
NP_057088                                                              16    7355
NP_000388                                                              15    9605
NP_570124                                                              15    9605
NP_001547                                                              15    9605
NP_001177649                                                           15    9605
NP_001554                                                              15    9605
NP_001269297                                                           15    9605
NP_001116325                                                           15    9605
NP_002996                                                              15    9605
NP_055887                                                              15    9605
NP_036443                                                              15    9605
NP_001157918                                                           15    9605
NP_588612                                                              15    9605
XP_006717498                                                           15    9605
XP_006717497                                                           15    9605
XP_005273551                                                           15    9605
XP_005273549                                                           15    9605
XP_005273547                                                           15    9605
XP_006715913                                                           15    9605
XP_005245497                                                           15    9605
XP_005245496                                                           15    9605
XP_005245495                                                           15    9605
XP_005245493                                                           15    9605
XP_005245492                                                           15    9605
NP_055632                                                              15    9605
>NP_006056
          Length = 398

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SELSKRNN 8
           SEL+KRNN
Sbjct: 93  SELTKRNN 100
>XP_005260701
          Length = 180

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  SELSKRNN 8
          SEL+KRNN
Sbjct: 92 SELTKRNN 99
>XP_005260700
          Length = 286

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  SELSKRNN 8
          SEL+KRNN
Sbjct: 92 SELTKRNN 99
>XP_005260698
          Length = 397

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  SELSKRNN 8
          SEL+KRNN
Sbjct: 92 SELTKRNN 99
>XP_006710313
          Length = 160

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  SELSKRNN 8
          SEL+KRNN
Sbjct: 76 SELTKRNN 83
>NP_001077379
          Length = 181

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SELSKRNN 8
           SEL+KRNN
Sbjct: 93  SELTKRNN 100
>NP_079133
          Length = 1844

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    ELSKRNN 8
            ELSKRNN
Sbjct: 1029 ELSKRNN 1035
>NP_001248396
          Length = 504

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SELSKRNNE 9
           S+ +KRNNE
Sbjct: 467 SKFAKRNNE 475
>NP_115517
          Length = 558

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SELSKRNNE 9
           S+ +KRNNE
Sbjct: 521 SKFAKRNNE 529
>NP_001153441
          Length = 582

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SELSKRNNE 9
           S LSK NNE
Sbjct: 414 STLSKVNNE 422
>NP_001972
          Length = 896

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SELSKRNNE 9
           S LSK NNE
Sbjct: 728 STLSKVNNE 736
>NP_005550
          Length = 3075

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    LSKRNNE 9
            LSK NNE
Sbjct: 1754 LSKHNNE 1760
>NP_060613
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SELSKRNNE 9
          SELS R NE
Sbjct: 78 SELSWRQNE 86
>XP_006710509
          Length = 658

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SELSKRNNE 9
           S LSK NNE
Sbjct: 490 STLSKVNNE 498
>XP_005270675
          Length = 866

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SELSKRNNE 9
           S LSK NNE
Sbjct: 698 STLSKVNNE 706
>NP_001231118
          Length = 1644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELSKRNN 8
           ELSKR N
Sbjct: 409 ELSKREN 415
>NP_001231121
          Length = 1504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELSKRNN 8
           ELSKR N
Sbjct: 312 ELSKREN 318
>NP_055564
          Length = 1472

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELSKRNN 8
           ELSKR N
Sbjct: 356 ELSKREN 362
>NP_001231119
          Length = 1533

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELSKRNN 8
           ELSKR N
Sbjct: 341 ELSKREN 347
>NP_001231120
          Length = 1463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELSKRNN 8
           ELSKR N
Sbjct: 271 ELSKREN 277
>NP_001231122
          Length = 1347

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELSKRNN 8
           ELSKR N
Sbjct: 216 ELSKREN 222
>NP_001177935
          Length = 173

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SELSKRNNE 9
           S++SK+ NE
Sbjct: 164 SQVSKKKNE 172
>NP_689830
          Length = 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ELSKRNNE 9
           E+SKR N+
Sbjct: 384 EISKRKNQ 391
>NP_851825
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SELSKRNN 8
           S LSKRN+
Sbjct: 289 SRLSKRNS 296
>NP_001229347
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SELSKRNN 8
           S LSKRN+
Sbjct: 362 SRLSKRNS 369
>NP_001229346
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SELSKRNN 8
           S LSKRN+
Sbjct: 381 SRLSKRNS 388
>NP_001229345
          Length = 520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SELSKRNN 8
           S LSKRN+
Sbjct: 289 SRLSKRNS 296
>NP_653175
          Length = 569

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SELSKRNN 8
           S LSKRN+
Sbjct: 350 SRLSKRNS 357
>NP_851808
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SELSKRNN 8
           S LSKRN+
Sbjct: 350 SRLSKRNS 357
>XP_005260474
          Length = 437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LSKRNNE 9
           LSKRN E
Sbjct: 269 LSKRNRE 275
>XP_006720406
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELSKRNN 8
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720405
          Length = 1347

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELSKRNN 8
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720404
          Length = 1477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELSKRNN 8
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720403
          Length = 1486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELSKRNN 8
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720402
          Length = 1487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELSKRNN 8
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720401
          Length = 1504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELSKRNN 8
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720400
          Length = 1526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELSKRNN 8
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720399
          Length = 1548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELSKRNN 8
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720376
          Length = 334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SELSKRNN 8
           S LSKRN+
Sbjct: 93  SRLSKRNS 100
>XP_006720375
          Length = 334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SELSKRNN 8
           S LSKRN+
Sbjct: 93  SRLSKRNS 100
>XP_006720374
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SELSKRNN 8
           S LSKRN+
Sbjct: 177 SRLSKRNS 184
>XP_006720373
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SELSKRNN 8
           S LSKRN+
Sbjct: 177 SRLSKRNS 184
>XP_006720372
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SELSKRNN 8
           S LSKRN+
Sbjct: 177 SRLSKRNS 184
>XP_006720371
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SELSKRNN 8
           S LSKRN+
Sbjct: 289 SRLSKRNS 296
>XP_006720370
          Length = 584

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SELSKRNN 8
           S LSKRN+
Sbjct: 350 SRLSKRNS 357
>XP_006720369
          Length = 591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SELSKRNN 8
           S LSKRN+
Sbjct: 350 SRLSKRNS 357
>XP_006710362
          Length = 172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SELSKRNNE 9
           S++SK+ NE
Sbjct: 163 SQVSKKKNE 171
>NP_057088
          Length = 437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LSKRNNE 9
           LSKRN E
Sbjct: 269 LSKRNRE 275
>NP_000388
          Length = 570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SELSKRNNE 9
           SEL  R NE
Sbjct: 142 SELGDRQNE 150
>NP_570124
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SELSKRN 7
           SE++KRN
Sbjct: 219 SEIAKRN 225
>NP_001547
          Length = 756

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ELSKRNNE 9
          ELS RN E
Sbjct: 49 ELSPRNRE 56
>NP_001177649
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ELSKRNNE 9
          ELS RN E
Sbjct: 47 ELSPRNRE 54
>NP_001554
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LSKRNNE 9
           +SKRN+E
Sbjct: 774 ISKRNSE 780
>NP_001269297
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LSKRNNE 9
           +SKRN+E
Sbjct: 696 ISKRNSE 702
>NP_001116325
          Length = 251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  ELSKRNN 8
          ELS RNN
Sbjct: 40 ELSLRNN 46
>NP_002996
          Length = 830

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SKRNNE 9
           +KRNNE
Sbjct: 124 NKRNNE 129
>NP_055887
          Length = 1281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SELSKRNN 8
           S++SK NN
Sbjct: 822 SKISKNNN 829
>NP_036443
          Length = 393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SELSKRNNE 9
           +ELS+ N+E
Sbjct: 192 TELSRENDE 200
>NP_001157918
          Length = 1188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SELSKRNN 8
           +ELS+R+N
Sbjct: 927 TELSRRHN 934
>NP_588612
          Length = 251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  ELSKRNN 8
          ELS RNN
Sbjct: 40 ELSLRNN 46
>XP_006717498
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SELSKRNNE 9
          +ELS+ N+E
Sbjct: 86 TELSRENDE 94
>XP_006717497
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SELSKRNNE 9
           +ELS+ N+E
Sbjct: 192 TELSRENDE 200
>XP_005273551
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ELSKRNNE 9
          ELS RN E
Sbjct: 49 ELSPRNRE 56
>XP_005273549
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ELSKRNNE 9
          ELS RN E
Sbjct: 49 ELSPRNRE 56
>XP_005273547
          Length = 805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ELSKRNNE 9
          ELS RN E
Sbjct: 49 ELSPRNRE 56
>XP_006715913
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SELSKRN 7
          SE++KRN
Sbjct: 11 SEIAKRN 17
>XP_005245497
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SKRNNE 9
           +KRNNE
Sbjct: 124 NKRNNE 129
>XP_005245496
          Length = 790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SKRNNE 9
           +KRNNE
Sbjct: 124 NKRNNE 129
>XP_005245495
          Length = 790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SKRNNE 9
           +KRNNE
Sbjct: 124 NKRNNE 129
>XP_005245493
          Length = 830

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SKRNNE 9
           +KRNNE
Sbjct: 124 NKRNNE 129
>XP_005245492
          Length = 830

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SKRNNE 9
           +KRNNE
Sbjct: 124 NKRNNE 129
>NP_055632
          Length = 811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELSKRNN 8
           ELS RNN
Sbjct: 329 ELSLRNN 335
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.281    0.104    0.236 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 531,780
Number of extensions: 990
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.6 bits)
S2: 28 (15.4 bits)

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