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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001167558                                                           18    1935
NP_858045                                                              18    1935
NP_006525                                                              18    1935
NP_001167559                                                           18    1935
NP_065961                                                              17    4312
NP_001158137                                                           17    4312
XP_006716134                                                           17    4312
NP_079421                                                              16    7355
XP_005270233                                                           16    7355
XP_005270232                                                           16    7355
XP_005270231                                                           16    7355
XP_005270230                                                           16    7355
XP_005270229                                                           16    7355
XP_005270228                                                           16    7355
NP_036397                                                              15    9605
NP_060884                                                              15    9605
XP_006724287                                                           15    9605
XP_005261561                                                           15    9605

>NP_001167558
          Length = 1423

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SEGVETSLL 9
           SEGV TSLL
Sbjct: 530 SEGVGTSLL 538



>NP_858045
          Length = 1424

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SEGVETSLL 9
           SEGV TSLL
Sbjct: 530 SEGVGTSLL 538



>NP_006525
          Length = 1420

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SEGVETSLL 9
           SEGV TSLL
Sbjct: 530 SEGVGTSLL 538



>NP_001167559
          Length = 1415

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SEGVETSLL 9
           SEGV TSLL
Sbjct: 540 SEGVGTSLL 548



>NP_065961
          Length = 1934

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SEGVETSL 8
           +EGVET+L
Sbjct: 274 TEGVETTL 281



>NP_001158137
          Length = 1950

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SEGVETSL 8
           +EGVET+L
Sbjct: 274 TEGVETTL 281



>XP_006716134
          Length = 1847

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SEGVETSL 8
           +EGVET+L
Sbjct: 198 TEGVETTL 205



>NP_079421
          Length = 1665

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GVETSLL 9
           GV+TSLL
Sbjct: 987 GVDTSLL 993



>XP_005270233
          Length = 927

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GVETSLL 9
           GV+TSLL
Sbjct: 249 GVDTSLL 255



>XP_005270232
          Length = 1535

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GVETSLL 9
           GV+TSLL
Sbjct: 988 GVDTSLL 994



>XP_005270231
          Length = 1627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GVETSLL 9
           GV+TSLL
Sbjct: 949 GVDTSLL 955



>XP_005270230
          Length = 1627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GVETSLL 9
           GV+TSLL
Sbjct: 949 GVDTSLL 955



>XP_005270229
          Length = 1637

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GVETSLL 9
           GV+TSLL
Sbjct: 988 GVDTSLL 994



>XP_005270228
          Length = 1666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GVETSLL 9
           GV+TSLL
Sbjct: 988 GVDTSLL 994



>NP_036397
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EGVETSLL 9
           EG++ SLL
Sbjct: 299 EGIQASLL 306



>NP_060884
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SEGVETSLL 9
          S+GV+ SLL
Sbjct: 12 SQGVQWSLL 20



>XP_006724287
          Length = 258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EGVETSLL 9
           EG++ SLL
Sbjct: 171 EGIQASLL 178



>XP_005261561
          Length = 389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EGVETSLL 9
           EG++ SLL
Sbjct: 302 EGIQASLL 309



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.293    0.118    0.272 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 513,364
Number of extensions: 913
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)