Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              19     869
NP_444254                                                              19     869
NP_444253                                                              19     869
NP_444255                                                              19     869
NP_444260                                                              19     869
XP_005247551                                                           19     869
XP_005247550                                                           19     869
XP_005247549                                                           19     869
NP_001273206                                                           18    1935
NP_001273207                                                           18    1935
NP_001273208                                                           18    1935
NP_006313                                                              18    1935
XP_005268350                                                           18    1935
NP_057724                                                              16    5631
NP_444259                                                              16    7355
NP_001269462                                                           16    7355
NP_001076                                                              16    7355
XP_005260950                                                           16    7355
XP_005260949                                                           16    7355
XP_005260948                                                           16    7355
XP_005260947                                                           16    7355
XP_006713712                                                           16    7355
NP_777567                                                              16    7355
NP_003267                                                              15    9605
NP_783195                                                              15    9605
NP_006522                                                              15    9605
NP_055970                                                              15    9605
NP_064506                                                              15    9605
NP_056400                                                              15    9605
NP_848611                                                              15    9605
NP_620125                                                              15    9605
NP_001245233                                                           15    9605
NP_001245234                                                           15    9605
NP_001245235                                                           15    9605
NP_001073920                                                           15    9605
XP_005260753                                                           15    9605
XP_005260752                                                           15    9605
XP_005260751                                                           15    9605
XP_005260750                                                           15    9605
XP_005260749                                                           15    9605
XP_005260748                                                           15    9605
XP_005260747                                                           15    9605
XP_005260746                                                           15    9605
XP_005260745                                                           15    9605
XP_005266612                                                           15    9605
XP_006719933                                                           15    9605
XP_006719932                                                           15    9605
XP_005266610                                                           15    9605
XP_005266609                                                           15    9605
XP_005266608                                                           15    9605
XP_005266607                                                           15    9605
XP_005266606                                                           15    9605
XP_005266605                                                           15    9605
XP_005266604                                                           15    9605
XP_005266603                                                           15    9605
XP_006717499                                                           15    9605
XP_005252492                                                           15    9605
XP_005252490                                                           15    9605
XP_005252489                                                           15    9605
XP_005252488                                                           15    9605
XP_005263894                                                           15    9605
XP_006712894                                                           15    9605
XP_006712893                                                           15    9605
XP_006712892                                                           15    9605
XP_005263892                                                           15    9605
XP_006712891                                                           15    9605
XP_005263893                                                           15    9605
>NP_444256
          Length = 1794

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SEADVSQAF 9
            SE DVSQAF
Sbjct: 1668 SEEDVSQAF 1676
>NP_444254
          Length = 1845

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SEADVSQAF 9
            SE DVSQAF
Sbjct: 1719 SEEDVSQAF 1727
>NP_444253
          Length = 1914

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SEADVSQAF 9
            SE DVSQAF
Sbjct: 1788 SEEDVSQAF 1796
>NP_444255
          Length = 1863

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SEADVSQAF 9
            SE DVSQAF
Sbjct: 1737 SEEDVSQAF 1745
>NP_444260
          Length = 154

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SEADVSQAF 9
          SE DVSQAF
Sbjct: 28 SEEDVSQAF 36
>XP_005247551
          Length = 1855

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SEADVSQAF 9
            SE DVSQAF
Sbjct: 1729 SEEDVSQAF 1737
>XP_005247550
          Length = 1856

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SEADVSQAF 9
            SE DVSQAF
Sbjct: 1730 SEEDVSQAF 1738
>XP_005247549
          Length = 1924

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SEADVSQAF 9
            SE DVSQAF
Sbjct: 1798 SEEDVSQAF 1806
>NP_001273206
          Length = 897

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  SEADVSQAF 9
          SEADV+Q F
Sbjct: 24 SEADVAQQF 32
>NP_001273207
          Length = 824

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  SEADVSQAF 9
          SEADV+Q F
Sbjct: 24 SEADVAQQF 32
>NP_001273208
          Length = 439

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  SEADVSQAF 9
          SEADV+Q F
Sbjct: 24 SEADVAQQF 32
>NP_006313
          Length = 907

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  SEADVSQAF 9
          SEADV+Q F
Sbjct: 24 SEADVAQQF 32
>XP_005268350
          Length = 818

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  SEADVSQAF 9
          SEADV+Q F
Sbjct: 24 SEADVAQQF 32
>NP_057724
          Length = 439

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SEADVSQAF 9
           SEADV++ F
Sbjct: 347 SEADVTRPF 355
>NP_444259
          Length = 153

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  DVSQAF 9
          DVSQAF
Sbjct: 30 DVSQAF 35
>NP_001269462
          Length = 627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           S+ADVSQ
Sbjct: 413 SQADVSQ 419
>NP_001076
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SEADVSQAF 9
           SEA++ Q+F
Sbjct: 111 SEAEIHQSF 119
>XP_005260950
          Length = 673

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           S+ADVSQ
Sbjct: 459 SQADVSQ 465
>XP_005260949
          Length = 673

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           S+ADVSQ
Sbjct: 459 SQADVSQ 465
>XP_005260948
          Length = 682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           S+ADVSQ
Sbjct: 468 SQADVSQ 474
>XP_005260947
          Length = 703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           S+ADVSQ
Sbjct: 489 SQADVSQ 495
>XP_006713712
          Length = 1923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    DVSQAF 9
            DVSQAF
Sbjct: 1800 DVSQAF 1805
>NP_777567
          Length = 417

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EADVSQA 8
           E+DVSQA
Sbjct: 348 ESDVSQA 354
>NP_003267
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EADVSQA 8
           +AD+SQA
Sbjct: 594 QADISQA 600
>NP_783195
          Length = 833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EADVSQAF 9
           E D SQAF
Sbjct: 608 EGDKSQAF 615
>NP_006522
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EADVSQAF 9
           E D SQAF
Sbjct: 599 EGDKSQAF 606
>NP_055970
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SEADVSQAF 9
           +EAD  QA+
Sbjct: 281 TEADAQQAY 289
>NP_064506
          Length = 1516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EADVSQAF 9
           E D+S+AF
Sbjct: 547 EFDISEAF 554
>NP_056400
          Length = 1237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           +EAD+SQ
Sbjct: 781 TEADISQ 787
>NP_848611
          Length = 746

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   EADVSQ 7
           EADVSQ
Sbjct: 359 EADVSQ 364
>NP_620125
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           S+ADVSQ
Sbjct: 196 SKADVSQ 202
>NP_001245233
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           S+ADVSQ
Sbjct: 238 SKADVSQ 244
>NP_001245234
          Length = 272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           S+ADVSQ
Sbjct: 196 SKADVSQ 202
>NP_001245235
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           S+ADVSQ
Sbjct: 130 SKADVSQ 136
>NP_001073920
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   EADVSQAF 9
           EAD+ Q F
Sbjct: 112 EADIHQGF 119
>XP_005260753
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           +EAD+SQ
Sbjct: 390 TEADISQ 396
>XP_005260752
          Length = 1046

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           +EAD+SQ
Sbjct: 590 TEADISQ 596
>XP_005260751
          Length = 1060

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           +EAD+SQ
Sbjct: 604 TEADISQ 610
>XP_005260750
          Length = 1180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           +EAD+SQ
Sbjct: 786 TEADISQ 792
>XP_005260749
          Length = 1211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           +EAD+SQ
Sbjct: 755 TEADISQ 761
>XP_005260748
          Length = 1216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           +EAD+SQ
Sbjct: 760 TEADISQ 766
>XP_005260747
          Length = 1217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           +EAD+SQ
Sbjct: 761 TEADISQ 767
>XP_005260746
          Length = 1237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           +EAD+SQ
Sbjct: 781 TEADISQ 787
>XP_005260745
          Length = 1242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           +EAD+SQ
Sbjct: 786 TEADISQ 792
>XP_005266612
          Length = 805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EADVSQAF 9
           E D SQAF
Sbjct: 580 EGDKSQAF 587
>XP_006719933
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EADVSQAF 9
           E D SQAF
Sbjct: 599 EGDKSQAF 606
>XP_006719932
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EADVSQAF 9
           E D SQAF
Sbjct: 599 EGDKSQAF 606
>XP_005266610
          Length = 833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EADVSQAF 9
           E D SQAF
Sbjct: 608 EGDKSQAF 615
>XP_005266609
          Length = 843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EADVSQAF 9
           E D SQAF
Sbjct: 656 EGDKSQAF 663
>XP_005266608
          Length = 844

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EADVSQAF 9
           E D SQAF
Sbjct: 656 EGDKSQAF 663
>XP_005266607
          Length = 844

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EADVSQAF 9
           E D SQAF
Sbjct: 619 EGDKSQAF 626
>XP_005266606
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EADVSQAF 9
           E D SQAF
Sbjct: 622 EGDKSQAF 629
>XP_005266605
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EADVSQAF 9
           E D SQAF
Sbjct: 627 EGDKSQAF 634
>XP_005266604
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EADVSQAF 9
           E D SQAF
Sbjct: 637 EGDKSQAF 644
>XP_005266603
          Length = 881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EADVSQAF 9
           E D SQAF
Sbjct: 656 EGDKSQAF 663
>XP_006717499
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SEADVSQAF 9
           +EAD  QA+
Sbjct: 124 TEADAQQAY 132
>XP_005252492
          Length = 650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SEADVSQAF 9
           +EAD  QA+
Sbjct: 158 TEADAQQAY 166
>XP_005252490
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SEADVSQAF 9
           +EAD  QA+
Sbjct: 304 TEADAQQAY 312
>XP_005252489
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SEADVSQAF 9
           +EAD  QA+
Sbjct: 281 TEADAQQAY 289
>XP_005252488
          Length = 796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SEADVSQAF 9
           +EAD  QA+
Sbjct: 304 TEADAQQAY 312
>XP_005263894
          Length = 210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  SEADVSQ 7
          S+ADVSQ
Sbjct: 28 SKADVSQ 34
>XP_006712894
          Length = 298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           S+ADVSQ
Sbjct: 116 SKADVSQ 122
>XP_006712893
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           S+ADVSQ
Sbjct: 238 SKADVSQ 244
>XP_006712892
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           S+ADVSQ
Sbjct: 238 SKADVSQ 244
>XP_005263892
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           S+ADVSQ
Sbjct: 172 SKADVSQ 178
>XP_006712891
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           S+ADVSQ
Sbjct: 238 SKADVSQ 244
>XP_005263893
          Length = 480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEADVSQ 7
           S+ADVSQ
Sbjct: 298 SKADVSQ 304
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.110    0.262 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 321,772
Number of extensions: 340
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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