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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_078966                                                              18    1935
NP_005179                                                              18    1935
NP_077321                                                              17    4312
NP_004851                                                              17    4312
NP_001273739                                                           17    4312
XP_005251635                                                           17    4312
NP_056324                                                              17    4312
NP_149016                                                              16    5631
NP_060959                                                              16    5631
XP_005265460                                                           16    5631
XP_005245394                                                           16    5631
XP_005245393                                                           16    5631
XP_006711515                                                           16    5631
XP_006711514                                                           16    5631
XP_006711513                                                           16    5631
NP_003244                                                              16    7355
NP_149038                                                              16    7355
NP_056150                                                              16    7355
XP_005261097                                                           16    7355
XP_005261096                                                           16    7355
XP_005261095                                                           16    7355
XP_005261094                                                           16    7355
XP_006719370                                                           16    7355
XP_006719369                                                           16    7355
XP_006719368                                                           16    7355
NP_006075                                                              15    9605
XP_005276320                                                           15    9605
XP_005276319                                                           15    9605
XP_005276318                                                           15    9605
XP_005276317                                                           15    9605
XP_006725067                                                           15    9605
XP_006725066                                                           15    9605
XP_006725065                                                           15    9605
XP_006725064                                                           15    9605
XP_005248451                                                           15    9605
XP_005248450                                                           15    9605
XP_005248449                                                           15    9605
XP_005248448                                                           15    9605
XP_006710226                                                           15    9605

>NP_078966
          Length = 14507

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SDISTASSS 9
            SD STASSS
Sbjct: 2920 SDASTASSS 2928



>NP_005179
          Length = 906

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SDISTASSS 9
           SDIS ASSS
Sbjct: 791 SDISNASSS 799



>NP_077321
          Length = 559

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SDISTASSS 9
           SD++T+SSS
Sbjct: 351 SDLTTSSSS 359



>NP_004851
          Length = 673

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SDISTASSS 9
           SD+STAS +
Sbjct: 447 SDVSTASET 455



>NP_001273739
          Length = 386

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SDISTASSS 9
           SD++T+SSS
Sbjct: 178 SDLTTSSSS 186



>XP_005251635
          Length = 493

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SDISTASSS 9
           SD++T+SSS
Sbjct: 285 SDLTTSSSS 293



>NP_056324
          Length = 275

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   DISTASSS 9
           D STASSS
Sbjct: 254 DFSTASSS 261



>NP_149016
          Length = 589

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SDISTASSS 9
           +D STASSS
Sbjct: 353 TDSSTASSS 361



>NP_060959
          Length = 2964

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SDISTASS 8
           SD+STA S
Sbjct: 538 SDVSTAKS 545



>XP_005265460
          Length = 589

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SDISTASSS 9
           +D STASSS
Sbjct: 353 TDSSTASSS 361



>XP_005245394
          Length = 1741

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SDISTASS 8
           SD+STA S
Sbjct: 538 SDVSTAKS 545



>XP_005245393
          Length = 2663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SDISTASS 8
           SD+STA S
Sbjct: 538 SDVSTAKS 545



>XP_006711515
          Length = 2904

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SDISTASS 8
           SD+STA S
Sbjct: 538 SDVSTAKS 545



>XP_006711514
          Length = 2964

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SDISTASS 8
           SD+STA S
Sbjct: 538 SDVSTAKS 545



>XP_006711513
          Length = 2964

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SDISTASS 8
           SD+STA S
Sbjct: 538 SDVSTAKS 545



>NP_003244
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SDISTASSS 9
          S++ST SSS
Sbjct: 52 SEVSTRSSS 60



>NP_149038
          Length = 512

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SDISTASS 8
           SDI TASS
Sbjct: 118 SDIITASS 125



>NP_056150
          Length = 2210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SDISTASSS 9
            S IST SSS
Sbjct: 1597 SQISTTSSS 1605



>XP_005261097
          Length = 1452

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SDISTASSS 9
          S++ST SSS
Sbjct: 52 SEVSTRSSS 60



>XP_005261096
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SDISTASSS 9
          S++ST SSS
Sbjct: 52 SEVSTRSSS 60



>XP_005261095
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SDISTASSS 9
          S++ST SSS
Sbjct: 52 SEVSTRSSS 60



>XP_005261094
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SDISTASSS 9
          S++ST SSS
Sbjct: 52 SEVSTRSSS 60



>XP_006719370
          Length = 2076

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SDISTASSS 9
            S IST SSS
Sbjct: 1463 SQISTTSSS 1471



>XP_006719369
          Length = 2200

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SDISTASSS 9
            S IST SSS
Sbjct: 1587 SQISTTSSS 1595



>XP_006719368
          Length = 2209

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SDISTASSS 9
            S IST SSS
Sbjct: 1596 SQISTTSSS 1604



>NP_006075
          Length = 393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SDISTASSS 9
           SDI ++SSS
Sbjct: 177 SDIGSSSSS 185



>XP_005276320
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  DISTASSS 9
          DIS++SSS
Sbjct: 69 DISSSSSS 76




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 292 DISSSSSS 299



>XP_005276319
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 177 DISSSSSS 184




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 322 DISSSSSS 329




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 545 DISSSSSS 552



>XP_005276318
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 186 DISSSSSS 193




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 331 DISSSSSS 338




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 554 DISSSSSS 561



>XP_005276317
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 186 DISSSSSS 193




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 331 DISSSSSS 338




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 554 DISSSSSS 561



>XP_006725067
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 177 DISSSSSS 184




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 322 DISSSSSS 329




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 545 DISSSSSS 552



>XP_006725066
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 186 DISSSSSS 193




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 331 DISSSSSS 338




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 554 DISSSSSS 561



>XP_006725065
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 186 DISSSSSS 193




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 331 DISSSSSS 338




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 554 DISSSSSS 561



>XP_006725064
          Length = 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 435 DISSSSSS 442



>XP_005248451
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  DISTASSS 9
          DIS++SSS
Sbjct: 69 DISSSSSS 76




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 292 DISSSSSS 299



>XP_005248450
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 177 DISSSSSS 184




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 322 DISSSSSS 329




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 545 DISSSSSS 552



>XP_005248449
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 186 DISSSSSS 193




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 331 DISSSSSS 338




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 554 DISSSSSS 561



>XP_005248448
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 186 DISSSSSS 193




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 331 DISSSSSS 338




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 554 DISSSSSS 561



>XP_006710226
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DISTASSS 9
           DIS++SSS
Sbjct: 244 DISSSSSS 251



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.268   0.0832    0.167 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 302,871
Number of extensions: 607
Number of successful extensions: 59
Number of sequences better than 10000.0: 39
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 19 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.4 bits)
S2: 28 (15.4 bits)