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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1482
NP_671714                                                              18    1482
XP_006715890                                                           18    1482
XP_005250160                                                           18    1482
XP_005250159                                                           18    1482
NP_056329                                                              17    2528
NP_001036100                                                           17    2528
NP_065969                                                              16    5631
NP_001231878                                                           16    5631
NP_001177875                                                           16    5631
XP_005270057                                                           16    5631
XP_005270056                                                           16    5631
XP_005270055                                                           16    5631
XP_006714948                                                           16    5631
XP_006714947                                                           16    5631
XP_006714946                                                           16    5631
XP_006714944                                                           16    5631
XP_006714943                                                           16    5631
XP_006714942                                                           16    5631
XP_006714941                                                           16    5631
XP_006714940                                                           16    5631
XP_006714939                                                           16    5631
XP_006714938                                                           16    5631
NP_878917                                                              16    7355
NP_878914                                                              16    7355
NP_878918                                                              16    7355
NP_001184033                                                           16    7355
NP_005924                                                              16    7355
NP_055995                                                              16    7355
XP_005267517                                                           16    7355
XP_005267516                                                           16    7355
XP_005267515                                                           16    7355
XP_005267514                                                           16    7355
XP_005267513                                                           16    7355
XP_005267512                                                           16    7355
XP_005267511                                                           16    7355

>NP_005742
          Length = 3907

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SDISALTL 8
            SDISALTL
Sbjct: 2599 SDISALTL 2606



>NP_671714
          Length = 3899

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SDISALTL 8
            SDISALTL
Sbjct: 2591 SDISALTL 2598



>XP_006715890
          Length = 3860

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SDISALTL 8
            SDISALTL
Sbjct: 2552 SDISALTL 2559



>XP_005250160
          Length = 3939

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SDISALTL 8
            SDISALTL
Sbjct: 2631 SDISALTL 2638



>XP_005250159
          Length = 3952

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    SDISALTL 8
            SDISALTL
Sbjct: 2644 SDISALTL 2651



>NP_056329
          Length = 311

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SDISALTLG 9
           SDISALT G
Sbjct: 276 SDISALTGG 284



>NP_001036100
          Length = 315

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SDISALTLG 9
           SDISALT G
Sbjct: 276 SDISALTGG 284



>NP_065969
          Length = 828

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2 DISALTLG 9
         D SALTLG
Sbjct: 2 DESALTLG 9



>NP_001231878
          Length = 828

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2 DISALTLG 9
         D SALTLG
Sbjct: 2 DESALTLG 9



>NP_001177875
          Length = 822

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DISALTLG 9
           D+S LTLG
Sbjct: 533 DLSPLTLG 540



>XP_005270057
          Length = 599

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2 DISALTLG 9
         D SALTLG
Sbjct: 2 DESALTLG 9



>XP_005270056
          Length = 789

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2 DISALTLG 9
         D SALTLG
Sbjct: 2 DESALTLG 9



>XP_005270055
          Length = 828

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2 DISALTLG 9
         D SALTLG
Sbjct: 2 DESALTLG 9



>XP_006714948
          Length = 448

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DISALTLG 9
           D+S LTLG
Sbjct: 159 DLSPLTLG 166



>XP_006714947
          Length = 448

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DISALTLG 9
           D+S LTLG
Sbjct: 159 DLSPLTLG 166



>XP_006714946
          Length = 448

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DISALTLG 9
           D+S LTLG
Sbjct: 159 DLSPLTLG 166



>XP_006714944
          Length = 586

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DISALTLG 9
           D+S LTLG
Sbjct: 297 DLSPLTLG 304



>XP_006714943
          Length = 789

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DISALTLG 9
           D+S LTLG
Sbjct: 500 DLSPLTLG 507



>XP_006714942
          Length = 789

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DISALTLG 9
           D+S LTLG
Sbjct: 500 DLSPLTLG 507



>XP_006714941
          Length = 789

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DISALTLG 9
           D+S LTLG
Sbjct: 500 DLSPLTLG 507



>XP_006714940
          Length = 789

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DISALTLG 9
           D+S LTLG
Sbjct: 500 DLSPLTLG 507



>XP_006714939
          Length = 789

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DISALTLG 9
           D+S LTLG
Sbjct: 500 DLSPLTLG 507



>XP_006714938
          Length = 902

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DISALTLG 9
           D+S LTLG
Sbjct: 613 DLSPLTLG 620



>NP_878917
          Length = 556

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SDISALT 7
           SDISA+T
Sbjct: 215 SDISAIT 221



>NP_878914
          Length = 429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  SDISALT 7
          SDISA+T
Sbjct: 89 SDISAIT 95



>NP_878918
          Length = 6907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SDISALT 7
            SDISA+T
Sbjct: 6581 SDISAIT 6587



>NP_001184033
          Length = 3972

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SDISALTLG 9
           +DI+++TLG
Sbjct: 943 TDITSVTLG 951



>NP_005924
          Length = 3969

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SDISALTLG 9
           +DI+++TLG
Sbjct: 943 TDITSVTLG 951



>NP_055995
          Length = 6885

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SDISALT 7
            SDISA+T
Sbjct: 6558 SDISAIT 6564



>XP_005267517
          Length = 6883

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SDISALT 7
            SDISA+T
Sbjct: 6542 SDISAIT 6548



>XP_005267516
          Length = 6884

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SDISALT 7
            SDISA+T
Sbjct: 6558 SDISAIT 6564



>XP_005267515
          Length = 6899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SDISALT 7
            SDISA+T
Sbjct: 6558 SDISAIT 6564



>XP_005267514
          Length = 6908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SDISALT 7
            SDISA+T
Sbjct: 6581 SDISAIT 6587



>XP_005267513
          Length = 6921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SDISALT 7
            SDISA+T
Sbjct: 6581 SDISAIT 6587



>XP_005267512
          Length = 6922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SDISALT 7
            SDISA+T
Sbjct: 6581 SDISAIT 6587



>XP_005267511
          Length = 6922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    SDISALT 7
            SDISA+T
Sbjct: 6581 SDISAIT 6587



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.128    0.316 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 307,672
Number of extensions: 372
Number of successful extensions: 36
Number of sequences better than 10000.0: 36
Number of HSP's gapped: 36
Number of HSP's successfully gapped: 36
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)