Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              20     509
NP_444254                                                              20     509
NP_444253                                                              20     509
NP_444255                                                              20     509
XP_005247551                                                           20     509
XP_005247550                                                           20     509
XP_006713712                                                           20     509
XP_005247549                                                           20     509
NP_001231892                                                           16    5631
NP_001104488                                                           16    5631
NP_001104489                                                           16    5631
NP_660093                                                              16    5631
NP_892009                                                              16    5631
XP_005253271                                                           16    5631
XP_006718431                                                           16    5631
XP_006718430                                                           16    5631
XP_006718429                                                           16    5631
XP_006718428                                                           16    5631
XP_006718427                                                           16    5631
NP_004490                                                              16    5631
NP_112556                                                              16    5631
NP_079321                                                              16    7355
NP_001171559                                                           16    7355
NP_003889                                                              16    7355
NP_061330                                                              16    7355
NP_004506                                                              16    7355
NP_001254738                                                           16    7355
NP_619636                                                              16    7355
XP_005261808                                                           16    7355
XP_005267257                                                           16    7355
XP_005267256                                                           16    7355
XP_005267255                                                           16    7355
XP_005267254                                                           16    7355
XP_006715654                                                           16    7355
NP_733751                                                              15    9605
NP_001071107                                                           15    9605
NP_060148                                                              15    9605
XP_005259057                                                           15    9605
XP_005259056                                                           15    9605
XP_006723307                                                           15    9605
XP_005259055                                                           15    9605
XP_006716142                                                           15    9605
XP_005250088                                                           15    9605
XP_006716141                                                           15    9605
XP_005250085                                                           15    9605
XP_006716140                                                           15    9605
XP_005250084                                                           15    9605
XP_005250083                                                           15    9605
XP_005250082                                                           15    9605
NP_059128                                                              15    9605
>NP_444256
          Length = 1794

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SDATVKMKP 9
            SDATVK KP
Sbjct: 1149 SDATVKKKP 1157
>NP_444254
          Length = 1845

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SDATVKMKP 9
            SDATVK KP
Sbjct: 1149 SDATVKKKP 1157
>NP_444253
          Length = 1914

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SDATVKMKP 9
            SDATVK KP
Sbjct: 1218 SDATVKKKP 1226
>NP_444255
          Length = 1863

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SDATVKMKP 9
            SDATVK KP
Sbjct: 1218 SDATVKKKP 1226
>XP_005247551
          Length = 1855

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SDATVKMKP 9
            SDATVK KP
Sbjct: 1159 SDATVKKKP 1167
>XP_005247550
          Length = 1856

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SDATVKMKP 9
            SDATVK KP
Sbjct: 1228 SDATVKKKP 1236
>XP_006713712
          Length = 1923

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SDATVKMKP 9
            SDATVK KP
Sbjct: 1228 SDATVKKKP 1236
>XP_005247549
          Length = 1924

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SDATVKMKP 9
            SDATVK KP
Sbjct: 1228 SDATVKKKP 1236
>NP_001231892
          Length = 2488

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SDATVKMKP 9
            SD+ +KM+P
Sbjct: 1019 SDSGIKMEP 1027
>NP_001104488
          Length = 2365

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SDATVKMKP 9
           SD+ +KM+P
Sbjct: 932 SDSGIKMEP 940
>NP_001104489
          Length = 1493

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SDATVKMKP 9
          SD+ +KM+P
Sbjct: 82 SDSGIKMEP 90
>NP_660093
          Length = 2429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SDATVKMKP 9
            SD+ +KM+P
Sbjct: 996  SDSGIKMEP 1004
>NP_892009
          Length = 2432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SDATVKMKP 9
            SD+ +KM+P
Sbjct: 996  SDSGIKMEP 1004
>XP_005253271
          Length = 1481

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SDATVKMKP 9
          SD+ +KM+P
Sbjct: 82 SDSGIKMEP 90
>XP_006718431
          Length = 1493

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SDATVKMKP 9
          SD+ +KM+P
Sbjct: 82 SDSGIKMEP 90
>XP_006718430
          Length = 1551

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  SDATVKMKP 9
          SD+ +KM+P
Sbjct: 82 SDSGIKMEP 90
>XP_006718429
          Length = 2416

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SDATVKMKP 9
           SD+ +KM+P
Sbjct: 947 SDSGIKMEP 955
>XP_006718428
          Length = 2455

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SDATVKMKP 9
            SD+ +KM+P
Sbjct: 1019 SDSGIKMEP 1027
>XP_006718427
          Length = 2465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SDATVKMKP 9
            SD+ +KM+P
Sbjct: 996  SDSGIKMEP 1004
>NP_004490
          Length = 285

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   DATVKMKP 9
           D T+KM P
Sbjct: 98  DCTIKMDP 105
>NP_112556
          Length = 332

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   DATVKMKP 9
           D T+KM P
Sbjct: 98  DCTIKMDP 105
>NP_079321
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATVKMKP 9
           ATVK++P
Sbjct: 511 ATVKLRP 517
>NP_001171559
          Length = 1259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    SDATVKMKP 9
            SD T  MKP
Sbjct: 1157 SDGTKAMKP 1165
>NP_003889
          Length = 1496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    SDATVKMKP 9
            SD T  MKP
Sbjct: 1394 SDGTKAMKP 1402
>NP_061330
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATVKMKP 9
           ATVK++P
Sbjct: 493 ATVKLRP 499
>NP_004506
          Length = 390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SDATVKM 7
           SDATVK+
Sbjct: 169 SDATVKI 175
>NP_001254738
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SDATVKM 7
           SDATVK+
Sbjct: 131 SDATVKI 137
>NP_619636
          Length = 760

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ATVKMKP 9
           ATVK KP
Sbjct: 104 ATVKCKP 110
>XP_005261808
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATVKMKP 9
           ATVK++P
Sbjct: 511 ATVKLRP 517
>XP_005267257
          Length = 909

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SDATVKMKP 9
           SD T  MKP
Sbjct: 807 SDGTKAMKP 815
>XP_005267256
          Length = 1113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    SDATVKMKP 9
            SD T  MKP
Sbjct: 1011 SDGTKAMKP 1019
>XP_005267255
          Length = 1165

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    SDATVKMKP 9
            SD T  MKP
Sbjct: 1063 SDGTKAMKP 1071
>XP_005267254
          Length = 1443

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    SDATVKMKP 9
            SD T  MKP
Sbjct: 1341 SDGTKAMKP 1349
>XP_006715654
          Length = 1495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    SDATVKMKP 9
            SD T  MKP
Sbjct: 1393 SDGTKAMKP 1401
>NP_733751
          Length = 4911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TVKMKP 9
            TVK+KP
Sbjct: 4328 TVKLKP 4333
>NP_001071107
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ATVKMK 8
           ATVKMK
Sbjct: 333 ATVKMK 338
>NP_060148
          Length = 260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  ATVKMK 8
          ATVKMK
Sbjct: 49 ATVKMK 54
>XP_005259057
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SDATVKMK 8
           SD+T K+K
Sbjct: 109 SDSTAKLK 116
>XP_005259056
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SDATVKMK 8
           SD+T K+K
Sbjct: 109 SDSTAKLK 116
>XP_006723307
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SDATVKMK 8
           SD+T K+K
Sbjct: 124 SDSTAKLK 131
>XP_005259055
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SDATVKMK 8
           SD+T K+K
Sbjct: 124 SDSTAKLK 131
>XP_006716142
          Length = 4927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TVKMKP 9
            TVK+KP
Sbjct: 4344 TVKLKP 4349
>XP_005250088
          Length = 4928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TVKMKP 9
            TVK+KP
Sbjct: 4345 TVKLKP 4350
>XP_006716141
          Length = 4959

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TVKMKP 9
            TVK+KP
Sbjct: 4376 TVKLKP 4381
>XP_005250085
          Length = 4979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TVKMKP 9
            TVK+KP
Sbjct: 4400 TVKLKP 4405
>XP_006716140
          Length = 4982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TVKMKP 9
            TVK+KP
Sbjct: 4399 TVKLKP 4404
>XP_005250084
          Length = 4982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TVKMKP 9
            TVK+KP
Sbjct: 4399 TVKLKP 4404
>XP_005250083
          Length = 4982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TVKMKP 9
            TVK+KP
Sbjct: 4399 TVKLKP 4404
>XP_005250082
          Length = 4983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TVKMKP 9
            TVK+KP
Sbjct: 4400 TVKLKP 4405
>NP_059128
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SDATVKMK 8
           SD+T K+K
Sbjct: 109 SDSTAKLK 116
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.113    0.297 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 420,478
Number of extensions: 769
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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