Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443200                                                              16    5631
NP_001160070                                                           16    5631
XP_006718824                                                           16    5631
NP_001277162                                                           16    7355
NP_004594                                                              16    7355
NP_001159375                                                           16    7355
XP_005250609                                                           16    7355
NP_996888                                                              15    9605
NP_009053                                                              15    9605
NP_001263302                                                           15    9605
NP_001274745                                                           15    9605
XP_006725043                                                           15    9605
XP_006725041                                                           15    9605
XP_006725040                                                           15    9605
XP_006725039                                                           15    9605
XP_006725038                                                           15    9605
XP_006725037                                                           15    9605
XP_006711911                                                           15    9605
XP_006711910                                                           15    9605
XP_006711909                                                           15    9605
XP_006711908                                                           15    9605
XP_006711907                                                           15    9605
XP_006711906                                                           15    9605
XP_005245729                                                           15    9605
XP_005245726                                                           15    9605
XP_006711745                                                           15    9605
>NP_443200
          Length = 366

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SAYSATQS 8
          SA+SATQ+
Sbjct: 16 SAFSATQA 23
>NP_001160070
          Length = 366

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SAYSATQS 8
          SA+SATQ+
Sbjct: 16 SAFSATQA 23
>XP_006718824
          Length = 366

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SAYSATQS 8
          SA+SATQ+
Sbjct: 16 SAFSATQA 23
>NP_001277162
          Length = 286

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SAYSATQSA 9
           S+ SATQSA
Sbjct: 258 SSASATQSA 266
>NP_004594
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SAYSATQS 8
           S Y+ATQS
Sbjct: 132 SEYNATQS 139
>NP_001159375
          Length = 251

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SAYSATQS 8
           S Y+ATQS
Sbjct: 132 SEYNATQS 139
>XP_005250609
          Length = 280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SAYSATQS 8
           S Y+ATQS
Sbjct: 132 SEYNATQS 139
>NP_996888
          Length = 251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  SAYSATQS 8
          S Y ATQS
Sbjct: 23 SGYPATQS 30
>NP_009053
          Length = 310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  SAYSATQS 8
          S Y ATQS
Sbjct: 82 SGYPATQS 89
>NP_001263302
          Length = 310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  SAYSATQS 8
          S Y ATQS
Sbjct: 82 SGYPATQS 89
>NP_001274745
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    SAYSATQS 8
            S YS TQS
Sbjct: 995  SVYSKTQS 1002
>XP_006725043
          Length = 1593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AYSATQSA 9
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006725041
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AYSATQSA 9
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006725040
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AYSATQSA 9
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006725039
          Length = 1629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AYSATQSA 9
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006725038
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AYSATQSA 9
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006725037
          Length = 1656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AYSATQSA 9
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006711911
          Length = 1593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AYSATQSA 9
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006711910
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AYSATQSA 9
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006711909
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AYSATQSA 9
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006711908
          Length = 1629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AYSATQSA 9
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006711907
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AYSATQSA 9
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_006711906
          Length = 1656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AYSATQSA 9
           +YS TQSA
Sbjct: 445 SYSFTQSA 452
>XP_005245729
          Length = 1067

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SAYSATQS 8
           S YS TQS
Sbjct: 984 SVYSKTQS 991
>XP_005245726
          Length = 1095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    SAYSATQS 8
            S YS TQS
Sbjct: 995  SVYSKTQS 1002
>XP_006711745
          Length = 1170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    SAYSATQS 8
            S YS TQS
Sbjct: 995  SVYSKTQS 1002
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.281   0.0837    0.183 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 325,689
Number of extensions: 427
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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