Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001120690                                                           18    1135
NP_006221                                                              18    1135
NP_001243808                                                           18    1135
XP_006715808                                                           18    1135
NP_004361                                                              17    4312
XP_005249931                                                           17    4312
XP_005249930                                                           17    4312
XP_005249928                                                           17    4312
XP_006715397                                                           17    4312
NP_001265230                                                           16    7355
NP_001073917                                                           16    7355
NP_055456                                                              16    7355
XP_005275691                                                           16    7355
XP_005275688                                                           16    7355
XP_005275687                                                           16    7355
XP_005275686                                                           16    7355
XP_005275554                                                           16    7355
XP_005275551                                                           16    7355
XP_005275550                                                           16    7355
XP_005275549                                                           16    7355
XP_005275383                                                           16    7355
XP_005275380                                                           16    7355
XP_005275379                                                           16    7355
XP_005275378                                                           16    7355
XP_005275256                                                           16    7355
XP_005275255                                                           16    7355
XP_006725919                                                           16    7355
XP_005275253                                                           16    7355
XP_005275127                                                           16    7355
XP_005275124                                                           16    7355
XP_005275123                                                           16    7355
XP_005275122                                                           16    7355
XP_005272971                                                           16    7355
XP_005272968                                                           16    7355
XP_005272967                                                           16    7355
XP_005272966                                                           16    7355
XP_005274961                                                           16    7355
XP_005274958                                                           16    7355
XP_005274957                                                           16    7355
XP_005274956                                                           16    7355
XP_005249554                                                           16    7355
XP_005249551                                                           16    7355
XP_005249550                                                           16    7355
XP_005249549                                                           16    7355
XP_006713655                                                           16    7355
NP_000020                                                              15    9605
NP_001092882                                                           15    9605
NP_006757                                                              15    9605
NP_001092883                                                           15    9605
NP_001263180                                                           15    9605
NP_056243                                                              15    9605
NP_001273700                                                           15    9605
NP_115593                                                              15    9605
NP_001006657                                                           15    9605
NP_942592                                                              15    9605
NP_003260                                                              15    9605
NP_001273031                                                           15    9605
XP_005273706                                                           15    9605
XP_005265728                                                           15    9605
XP_005265724                                                           15    9605
XP_006712378                                                           15    9605
XP_005263945                                                           15    9605
XP_006712376                                                           15    9605
XP_006712375                                                           15    9605
XP_006712374                                                           15    9605
XP_006712371                                                           15    9605
>NP_001120690
          Length = 469

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SATQSACL 8
           SATQ+ACL
Sbjct: 432 SATQTACL 439
>NP_006221
          Length = 504

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SATQSACL 8
           SATQ+ACL
Sbjct: 467 SATQTACL 474
>NP_001243808
          Length = 469

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SATQSACL 8
           SATQ+ACL
Sbjct: 432 SATQTACL 439
>XP_006715808
          Length = 488

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SATQSACL 8
           SATQ+ACL
Sbjct: 451 SATQTACL 458
>NP_004361
          Length = 3063

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TQSACLR 9
           TQS CLR
Sbjct: 613 TQSICLR 619
>XP_005249931
          Length = 862

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SATQSACL 8
          +ATQS CL
Sbjct: 50 NATQSQCL 57
>XP_005249930
          Length = 888

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SATQSACL 8
          +ATQS CL
Sbjct: 50 NATQSQCL 57
>XP_005249928
          Length = 897

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SATQSACL 8
          +ATQS CL
Sbjct: 50 NATQSQCL 57
>XP_006715397
          Length = 2972

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TQSACLR 9
           TQS CLR
Sbjct: 613 TQSICLR 619
>NP_001265230
          Length = 379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TQSACLR 9
          TQ+ CLR
Sbjct: 72 TQNTCLR 78
>NP_001073917
          Length = 1130

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TQSACLR 9
          TQ+ CLR
Sbjct: 72 TQNTCLR 78
>NP_055456
          Length = 2089

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 751 ATQPFCLR 758
>XP_005275691
          Length = 1920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 772 ATQPFCLR 779
>XP_005275688
          Length = 2089

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 751 ATQPFCLR 758
>XP_005275687
          Length = 2109

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 771 ATQPFCLR 778
>XP_005275686
          Length = 2110

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 772 ATQPFCLR 779
>XP_005275554
          Length = 1920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 772 ATQPFCLR 779
>XP_005275551
          Length = 2089

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 751 ATQPFCLR 758
>XP_005275550
          Length = 2109

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 771 ATQPFCLR 778
>XP_005275549
          Length = 2110

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 772 ATQPFCLR 779
>XP_005275383
          Length = 1920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 772 ATQPFCLR 779
>XP_005275380
          Length = 2089

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 751 ATQPFCLR 758
>XP_005275379
          Length = 2109

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 771 ATQPFCLR 778
>XP_005275378
          Length = 2110

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 772 ATQPFCLR 779
>XP_005275256
          Length = 1899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 751 ATQPFCLR 758
>XP_005275255
          Length = 2088

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 750 ATQPFCLR 757
>XP_006725919
          Length = 2089

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 751 ATQPFCLR 758
>XP_005275253
          Length = 2089

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 751 ATQPFCLR 758
>XP_005275127
          Length = 1920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 772 ATQPFCLR 779
>XP_005275124
          Length = 2089

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 751 ATQPFCLR 758
>XP_005275123
          Length = 2109

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 771 ATQPFCLR 778
>XP_005275122
          Length = 2110

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 772 ATQPFCLR 779
>XP_005272971
          Length = 1920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 772 ATQPFCLR 779
>XP_005272968
          Length = 2089

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 751 ATQPFCLR 758
>XP_005272967
          Length = 2109

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 771 ATQPFCLR 778
>XP_005272966
          Length = 2110

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 772 ATQPFCLR 779
>XP_005274961
          Length = 1920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 772 ATQPFCLR 779
>XP_005274958
          Length = 2089

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 751 ATQPFCLR 758
>XP_005274957
          Length = 2109

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 771 ATQPFCLR 778
>XP_005274956
          Length = 2110

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 772 ATQPFCLR 779
>XP_005249554
          Length = 1920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 772 ATQPFCLR 779
>XP_005249551
          Length = 2089

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 751 ATQPFCLR 758
>XP_005249550
          Length = 2109

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 771 ATQPFCLR 778
>XP_005249549
          Length = 2110

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ATQSACLR 9
           ATQ  CLR
Sbjct: 772 ATQPFCLR 779
>XP_006713655
          Length = 1146

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TQSACLR 9
          TQ+ CLR
Sbjct: 72 TQNTCLR 78
>NP_000020
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   TQSACL 8
           T+SACL
Sbjct: 337 TESACL 342
>NP_001092882
          Length = 2004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SATQSACL 8
            S TQS+C+
Sbjct: 1597 SLTQSSCV 1604
>NP_006757
          Length = 2004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SATQSACL 8
            S TQS+C+
Sbjct: 1597 SLTQSSCV 1604
>NP_001092883
          Length = 2004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SATQSACL 8
            S TQS+C+
Sbjct: 1597 SLTQSSCV 1604
>NP_001263180
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  SATQSACL 8
          S+TQ  CL
Sbjct: 11 SSTQEGCL 18
>NP_056243
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   TQSACL 8
           TQS+CL
Sbjct: 768 TQSSCL 773
>NP_001273700
          Length = 2490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    ATQSAC 7
            +TQSAC
Sbjct: 2112 STQSAC 2117
>NP_115593
          Length = 2603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    ATQSAC 7
            +TQSAC
Sbjct: 2225 STQSAC 2230
>NP_001006657
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   TQSACL 8
           TQS+CL
Sbjct: 768 TQSSCL 773
>NP_942592
          Length = 2352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    ATQSAC 7
            +TQSAC
Sbjct: 1974 STQSAC 1979
>NP_003260
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATQSACLR 9
           AT+ ACL+
Sbjct: 282 ATEFACLK 289
>NP_001273031
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATQSACLR 9
           AT+ ACL+
Sbjct: 319 ATEFACLK 326
>XP_005273706
          Length = 1997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SATQSACL 8
            S TQS+C+
Sbjct: 1590 SLTQSSCV 1597
>XP_005265728
          Length = 2351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    ATQSAC 7
            +TQSAC
Sbjct: 1973 STQSAC 1978
>XP_005265724
          Length = 2602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    ATQSAC 7
            +TQSAC
Sbjct: 2224 STQSAC 2229
>XP_006712378
          Length = 671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ATQSAC 7
           ATQS+C
Sbjct: 635 ATQSSC 640
>XP_005263945
          Length = 671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ATQSAC 7
           ATQS+C
Sbjct: 635 ATQSSC 640
>XP_006712376
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ATQSAC 7
           ATQS+C
Sbjct: 641 ATQSSC 646
>XP_006712375
          Length = 685

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ATQSAC 7
           ATQS+C
Sbjct: 641 ATQSSC 646
>XP_006712374
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ATQSAC 7
           ATQS+C
Sbjct: 685 ATQSSC 690
>XP_006712371
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   ATQSAC 7
           ATQS+C
Sbjct: 685 ATQSSC 690
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.109    0.308 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 532,405
Number of extensions: 374
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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