Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004324                                                              19     869
XP_005250103                                                           19     869
XP_005250102                                                           19     869
NP_000746                                                              17    2528
NP_001244292                                                           17    2528
XP_005251766                                                           17    2528
XP_005251765                                                           17    2528
XP_005251764                                                           17    2528
XP_005251763                                                           17    2528
NP_002418                                                              15    9605
NP_001934                                                              15    9605
NP_055186                                                              15    9605
NP_054860                                                              15    9605
NP_001139192                                                           15    9605
XP_006715982                                                           15    9605
NP_689756                                                              15    9605
>NP_004324
          Length = 766

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SASMDSVTS 9
           SASMD+VTS
Sbjct: 114 SASMDTVTS 122
>XP_005250103
          Length = 758

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SASMDSVTS 9
           SASMD+VTS
Sbjct: 114 SASMDTVTS 122
>XP_005250102
          Length = 767

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SASMDSVTS 9
           SASMD+VTS
Sbjct: 114 SASMDTVTS 122
>NP_000746
          Length = 626

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SASMDSVT 8
           SASMDS+T
Sbjct: 470 SASMDSLT 477
>NP_001244292
          Length = 605

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SASMDSVT 8
           SASMDS+T
Sbjct: 449 SASMDSLT 456
>XP_005251766
          Length = 605

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SASMDSVT 8
           SASMDS+T
Sbjct: 449 SASMDSLT 456
>XP_005251765
          Length = 605

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SASMDSVT 8
           SASMDS+T
Sbjct: 449 SASMDSLT 456
>XP_005251764
          Length = 622

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SASMDSVT 8
           SASMDS+T
Sbjct: 466 SASMDSLT 473
>XP_005251763
          Length = 627

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   SASMDSVT 8
           SASMDS+T
Sbjct: 471 SASMDSLT 478
>NP_002418
          Length = 471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SASMDSVTS 9
           S S+D++TS
Sbjct: 287 SLSLDAITS 295
>NP_001934
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SMDSVTS 9
           S+DSVTS
Sbjct: 439 SVDSVTS 445
>NP_055186
          Length = 646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SASMDSVTS 9
          SAS DSV S
Sbjct: 85 SASADSVLS 93
>NP_054860
          Length = 1331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SASMDSVTS 9
           SASMD +++
Sbjct: 666 SASMDQISA 674
>NP_001139192
          Length = 495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SASMDSVTS 9
          +AS+D VTS
Sbjct: 65 TASLDIVTS 73
>XP_006715982
          Length = 827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SASMDSVTS 9
           SASMD +++
Sbjct: 162 SASMDQISA 170
>NP_689756
          Length = 186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ASMDSVT 8
           AS+DS+T
Sbjct: 106 ASLDSIT 112
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.280   0.0875    0.183 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 296,701
Number of extensions: 312
Number of successful extensions: 16
Number of sequences better than 10000.0: 16
Number of HSP's gapped: 16
Number of HSP's successfully gapped: 16
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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