Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              18    1935
NP_001120972                                                           18    1935
XP_006716054                                                           18    1935
XP_006716053                                                           18    1935
XP_006716052                                                           18    1935
XP_006716051                                                           18    1935
NP_001032208                                                           15    9605
NP_055729                                                              15    9605
NP_009045                                                              15    9605
XP_006712302                                                           15    9605
XP_006712301                                                           15    9605
XP_006712300                                                           15    9605
XP_005246116                                                           15    9605
XP_006712299                                                           15    9605
XP_005246115                                                           15    9605
XP_006712298                                                           15    9605
XP_006712297                                                           15    9605
>NP_000236
          Length = 1390

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SARSVSSTT 9
           SARSVS TT
Sbjct: 985 SARSVSPTT 993
>NP_001120972
          Length = 1408

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SARSVSSTT 9
            SARSVS TT
Sbjct: 1003 SARSVSPTT 1011
>XP_006716054
          Length = 960

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SARSVSSTT 9
           SARSVS TT
Sbjct: 555 SARSVSPTT 563
>XP_006716053
          Length = 960

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SARSVSSTT 9
           SARSVS TT
Sbjct: 555 SARSVSPTT 563
>XP_006716052
          Length = 1409

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SARSVSSTT 9
            SARSVS TT
Sbjct: 1004 SARSVSPTT 1012
>XP_006716051
          Length = 1427

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SARSVSSTT 9
            SARSVS TT
Sbjct: 1022 SARSVSPTT 1030
>NP_001032208
          Length = 857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SARSVSSTT 9
           S+ S+SSTT
Sbjct: 504 SSPSISSTT 512
>NP_055729
          Length = 804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SARSVSSTT 9
           S+ S+SSTT
Sbjct: 451 SSPSISSTT 459
>NP_009045
          Length = 1093

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ARSVSSTT 9
           ++SVSSTT
Sbjct: 761 SQSVSSTT 768
>XP_006712302
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SARSVSSTT 9
           S+ S+SSTT
Sbjct: 404 SSPSISSTT 412
>XP_006712301
          Length = 748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SARSVSSTT 9
           S+ S+SSTT
Sbjct: 370 SSPSISSTT 378
>XP_006712300
          Length = 748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SARSVSSTT 9
           S+ S+SSTT
Sbjct: 370 SSPSISSTT 378
>XP_005246116
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SARSVSSTT 9
           S+ S+SSTT
Sbjct: 455 SSPSISSTT 463
>XP_006712299
          Length = 833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SARSVSSTT 9
           S+ S+SSTT
Sbjct: 455 SSPSISSTT 463
>XP_005246115
          Length = 861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SARSVSSTT 9
           S+ S+SSTT
Sbjct: 508 SSPSISSTT 516
>XP_006712298
          Length = 882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SARSVSSTT 9
           S+ S+SSTT
Sbjct: 504 SSPSISSTT 512
>XP_006712297
          Length = 886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SARSVSSTT 9
           S+ S+SSTT
Sbjct: 508 SSPSISSTT 516
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.277   0.0829    0.169 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 190,757
Number of extensions: 274
Number of successful extensions: 17
Number of sequences better than 10000.0: 17
Number of HSP's gapped: 17
Number of HSP's successfully gapped: 17
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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