Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_073713                                                              19     665
NP_005145                                                              17    3301
NP_001122082                                                           17    3301
NP_001269978                                                           17    3301
XP_006720825                                                           17    3301
XP_006720824                                                           17    3301
NP_001177369                                                           17    4312
NP_006302                                                              17    4312
XP_006721667                                                           17    4312
XP_005256931                                                           17    4312
XP_005256930                                                           17    4312
XP_006721666                                                           17    4312
XP_005256929                                                           17    4312
XP_005256928                                                           17    4312
XP_006721665                                                           17    4312
XP_005256925                                                           17    4312
XP_005256924                                                           17    4312
XP_006721664                                                           17    4312
XP_005256923                                                           17    4312
NP_001128625                                                           16    5631
NP_689414                                                              16    5631
NP_666019                                                              16    5631
XP_005273523                                                           16    5631
XP_006716387                                                           16    5631
XP_005273522                                                           16    5631
XP_005273521                                                           16    5631
XP_005273520                                                           16    5631
XP_006716386                                                           16    5631
XP_006716176                                                           16    5631
XP_005250625                                                           16    5631
XP_005250624                                                           16    5631
XP_005250623                                                           16    5631
XP_006711002                                                           16    5631
NP_001121903                                                           16    5631
NP_001128626                                                           16    5631
NP_658988                                                              16    5631
NP_056174                                                              16    5631
NP_598408                                                              16    7355
NP_001035962                                                           16    7355
NP_001035961                                                           16    7355
NP_001008901                                                           16    7355
XP_005260355                                                           16    7355
XP_006720856                                                           16    7355
XP_005267190                                                           16    7355
XP_005267189                                                           16    7355
XP_005267187                                                           16    7355
XP_005267185                                                           16    7355
XP_005267184                                                           16    7355
NP_009055                                                              16    7355
NP_789761                                                              16    7355
NP_002373                                                              15    9605
NP_001257997                                                           15    9605
NP_660088                                                              15    9605
NP_660089                                                              15    9605
NP_660087                                                              15    9605
NP_689957                                                              15    9605
NP_932061                                                              15    9605
NP_001074295                                                           15    9605
NP_001257998                                                           15    9605
NP_001012279                                                           15    9605
NP_542763                                                              15    9605
NP_078788                                                              15    9605
XP_006722493                                                           15    9605
XP_006722491                                                           15    9605
XP_006722489                                                           15    9605
XP_006722487                                                           15    9605
XP_006722485                                                           15    9605
XP_006722484                                                           15    9605
XP_005266715                                                           15    9605
XP_005272427                                                           15    9605
XP_005272426                                                           15    9605
NP_001138424                                                           15    9605
>NP_073713
          Length = 985

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ARESIPSK 9
           ARESIPSK
Sbjct: 260 ARESIPSK 267
>NP_005145
          Length = 1118

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SARESIPSK 9
           S  ESIPSK
Sbjct: 338 SLEESIPSK 346
>NP_001122082
          Length = 1118

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SARESIPSK 9
           S  ESIPSK
Sbjct: 338 SLEESIPSK 346
>NP_001269978
          Length = 1012

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SARESIPSK 9
           S  ESIPSK
Sbjct: 261 SLEESIPSK 269
>XP_006720825
          Length = 1089

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SARESIPSK 9
           S  ESIPSK
Sbjct: 338 SLEESIPSK 346
>XP_006720824
          Length = 1118

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SARESIPSK 9
           S  ESIPSK
Sbjct: 338 SLEESIPSK 346
>NP_001177369
          Length = 2337

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    RESIPSK 9
            RESIP+K
Sbjct: 1542 RESIPAK 1548
>NP_006302
          Length = 2440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    RESIPSK 9
            RESIP+K
Sbjct: 1526 RESIPAK 1532
>XP_006721667
          Length = 2456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    RESIPSK 9
            RESIP+K
Sbjct: 1542 RESIPAK 1548
>XP_005256931
          Length = 2466

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    RESIPSK 9
            RESIP+K
Sbjct: 1552 RESIPAK 1558
>XP_005256930
          Length = 2508

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    RESIPSK 9
            RESIP+K
Sbjct: 1594 RESIPAK 1600
>XP_006721666
          Length = 2511

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    RESIPSK 9
            RESIP+K
Sbjct: 1610 RESIPAK 1616
>XP_005256929
          Length = 2514

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    RESIPSK 9
            RESIP+K
Sbjct: 1600 RESIPAK 1606
>XP_005256928
          Length = 2515

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    RESIPSK 9
            RESIP+K
Sbjct: 1601 RESIPAK 1607
>XP_006721665
          Length = 2523

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    RESIPSK 9
            RESIP+K
Sbjct: 1609 RESIPAK 1615
>XP_005256925
          Length = 2523

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    RESIPSK 9
            RESIP+K
Sbjct: 1609 RESIPAK 1615
>XP_005256924
          Length = 2524

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    RESIPSK 9
            RESIP+K
Sbjct: 1610 RESIPAK 1616
>XP_006721664
          Length = 2524

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    RESIPSK 9
            RESIP+K
Sbjct: 1610 RESIPAK 1616
>XP_005256923
          Length = 2524

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    RESIPSK 9
            RESIP+K
Sbjct: 1610 RESIPAK 1616
>NP_001128625
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARESIPSK 9
           A ES+PSK
Sbjct: 259 ASESLPSK 266
>NP_689414
          Length = 852

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SARESIPS 8
           SARE+ PS
Sbjct: 175 SARETFPS 182
>NP_666019
          Length = 473

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RESIPSK 9
           RES+P+K
Sbjct: 263 RESVPTK 269
>XP_005273523
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARESIPSK 9
           A ES+PSK
Sbjct: 259 ASESLPSK 266
>XP_006716387
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARESIPSK 9
           A ES+PSK
Sbjct: 259 ASESLPSK 266
>XP_005273522
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARESIPSK 9
           A ES+PSK
Sbjct: 259 ASESLPSK 266
>XP_005273521
          Length = 502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARESIPSK 9
           A ES+PSK
Sbjct: 269 ASESLPSK 276
>XP_005273520
          Length = 502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARESIPSK 9
           A ES+PSK
Sbjct: 269 ASESLPSK 276
>XP_006716386
          Length = 502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARESIPSK 9
           A ES+PSK
Sbjct: 269 ASESLPSK 276
>XP_006716176
          Length = 473

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RESIPSK 9
           RES+P+K
Sbjct: 263 RESVPTK 269
>XP_005250625
          Length = 473

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RESIPSK 9
           RES+P+K
Sbjct: 263 RESVPTK 269
>XP_005250624
          Length = 473

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RESIPSK 9
           RES+P+K
Sbjct: 263 RESVPTK 269
>XP_005250623
          Length = 473

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RESIPSK 9
           RES+P+K
Sbjct: 263 RESVPTK 269
>XP_006711002
          Length = 535

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SARESIPS 8
           SARE+ PS
Sbjct: 175 SARETFPS 182
>NP_001121903
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARESIPSK 9
           A ES+PSK
Sbjct: 259 ASESLPSK 266
>NP_001128626
          Length = 481

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARESIPSK 9
           A ES+PSK
Sbjct: 259 ASESLPSK 266
>NP_658988
          Length = 937

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RESIPSK 9
           +ESIPSK
Sbjct: 386 QESIPSK 392
>NP_056174
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARESIPSK 9
           A ES+PSK
Sbjct: 259 ASESLPSK 266
>NP_598408
          Length = 1150

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SARESIP 7
          S+RES+P
Sbjct: 46 SSRESVP 52
>NP_001035962
          Length = 1135

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SARESIP 7
          S+RES+P
Sbjct: 46 SSRESVP 52
>NP_001035961
          Length = 1141

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SARESIP 7
          S+RES+P
Sbjct: 37 SSRESVP 43
>NP_001008901
          Length = 123

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SARESIPSK 9
           SARE+ P K
Sbjct: 109 SARETSPQK 117
>XP_005260355
          Length = 103

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SARESIPSK 9
          SARE+ P K
Sbjct: 89 SARETSPQK 97
>XP_006720856
          Length = 1101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SARESIP 7
          S+RES+P
Sbjct: 46 SSRESVP 52
>XP_005267190
          Length = 3424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SARESIPS 8
           S+R+S+PS
Sbjct: 820 SSRQSLPS 827
>XP_005267189
          Length = 3425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SARESIPS 8
           S+R+S+PS
Sbjct: 834 SSRQSLPS 841
>XP_005267187
          Length = 3433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SARESIPS 8
           S+R+S+PS
Sbjct: 829 SSRQSLPS 836
>XP_005267185
          Length = 3437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SARESIPS 8
           S+R+S+PS
Sbjct: 833 SSRQSLPS 840
>XP_005267184
          Length = 3438

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SARESIPS 8
           S+R+S+PS
Sbjct: 834 SSRQSLPS 841
>NP_009055
          Length = 3433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SARESIPS 8
           S+R+S+PS
Sbjct: 829 SSRQSLPS 836
>NP_789761
          Length = 148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SARESIPSK 9
           SARE+ P K
Sbjct: 134 SARETSPQK 142
>NP_002373
          Length = 160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SARESIPS 8
          S R+S+PS
Sbjct: 45 SLRDSVPS 52
>NP_001257997
          Length = 87

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SARESIPS 8
          S R+S+PS
Sbjct: 36 SLRDSVPS 43
>NP_660088
          Length = 103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SARESIPS 8
          S R+S+PS
Sbjct: 45 SLRDSVPS 52
>NP_660089
          Length = 96

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SARESIPS 8
          S R+S+PS
Sbjct: 45 SLRDSVPS 52
>NP_660087
          Length = 151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SARESIPS 8
          S R+S+PS
Sbjct: 36 SLRDSVPS 43
>NP_689957
          Length = 2213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    RESIPS 8
            RES+PS
Sbjct: 1272 RESVPS 1277
>NP_932061
          Length = 83

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SARESIPS 8
          S R+S+PS
Sbjct: 45 SLRDSVPS 52
>NP_001074295
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RESIPSK 9
           RES+PS+
Sbjct: 229 RESLPSE 235
>NP_001257998
          Length = 74

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SARESIPS 8
          S R+S+PS
Sbjct: 36 SLRDSVPS 43
>NP_001012279
          Length = 947

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ESIPSK 9
           ES+PSK
Sbjct: 151 ESVPSK 156
>NP_542763
          Length = 137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RESIPSK 9
           RE+IP+K
Sbjct: 110 RETIPAK 116
>NP_078788
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RESIPS 8
           RES+PS
Sbjct: 355 RESVPS 360
>XP_006722493
          Length = 872

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RESIPS 8
           RES+PS
Sbjct: 460 RESVPS 465
>XP_006722491
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RESIPS 8
           RES+PS
Sbjct: 581 RESVPS 586
>XP_006722489
          Length = 1019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RESIPS 8
           RES+PS
Sbjct: 607 RESVPS 612
>XP_006722487
          Length = 1102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RESIPS 8
           RES+PS
Sbjct: 690 RESVPS 695
>XP_006722485
          Length = 1168

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RESIPS 8
           RES+PS
Sbjct: 756 RESVPS 761
>XP_006722484
          Length = 1252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RESIPS 8
           RES+PS
Sbjct: 840 RESVPS 845
>XP_005266715
          Length = 1272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RESIPS 8
           RES+PS
Sbjct: 860 RESVPS 865
>XP_005272427
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RESIPSK 9
           RES+PS+
Sbjct: 229 RESLPSE 235
>XP_005272426
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RESIPSK 9
           RES+PS+
Sbjct: 229 RESLPSE 235
>NP_001138424
          Length = 2172

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    RESIPS 8
            RES+PS
Sbjct: 1195 RESVPS 1200
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.291    0.106    0.254 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 675,430
Number of extensions: 1161
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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