Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_062541                                                              18    1135
NP_006268                                                              18    1135
NP_055833                                                              17    2528
NP_001186871                                                           17    2528
NP_002509                                                              17    2528
XP_006715463                                                           17    2528
XP_006715462                                                           17    2528
XP_006715461                                                           17    2528
XP_006715460                                                           17    2528
XP_006715459                                                           17    2528
XP_006715458                                                           17    2528
XP_006715457                                                           17    2528
XP_006715456                                                           17    2528
XP_005264018                                                           17    2528
XP_005264017                                                           17    2528
XP_005264016                                                           17    2528
XP_005264015                                                           17    2528
XP_005264014                                                           17    2528
XP_005264012                                                           17    2528
XP_005264011                                                           17    2528
XP_005264010                                                           17    2528
NP_060606                                                              17    3301
NP_001229285                                                           16    5631
NP_001229286                                                           16    5631
NP_001137531                                                           16    7355
NP_001137530                                                           16    7355
NP_057606                                                              16    7355
NP_001041674                                                           16    7355
XP_006718920                                                           16    7355
XP_006718919                                                           16    7355
XP_006718918                                                           16    7355
XP_005271639                                                           16    7355
XP_006718917                                                           16    7355
XP_005271637                                                           16    7355
XP_005271638                                                           16    7355
XP_006710019                                                           16    7355
NP_004381                                                              15    9605
NP_115640                                                              15    9605
NP_001243345                                                           15    9605
NP_001243346                                                           15    9605
NP_055592                                                              15    9605
NP_817123                                                              15    9605
XP_005254238                                                           15    9605
XP_005273417                                                           15    9605
XP_006711022                                                           15    9605
XP_006711021                                                           15    9605
XP_006711020                                                           15    9605
NP_001127925                                                           15    9605
>NP_062541
          Length = 1670

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    SAQFQMYRT 9
            +AQF+MY+T
Sbjct: 1456 NAQFKMYKT 1464
>NP_006268
          Length = 1697

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    SAQFQMYRT 9
            +AQF+MY+T
Sbjct: 1483 NAQFKMYKT 1491
>NP_055833
          Length = 2465

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    QFQMYR 8
            QFQMYR
Sbjct: 2318 QFQMYR 2323
>NP_001186871
          Length = 2476

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    QFQMYR 8
            QFQMYR
Sbjct: 2309 QFQMYR 2314
>NP_002509
          Length = 824

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAQFQMYRT 9
           SAQF M++T
Sbjct: 496 SAQFSMFQT 504
>XP_006715463
          Length = 2434

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    QFQMYR 8
            QFQMYR
Sbjct: 2267 QFQMYR 2272
>XP_006715462
          Length = 2452

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    QFQMYR 8
            QFQMYR
Sbjct: 2285 QFQMYR 2290
>XP_006715461
          Length = 2456

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    QFQMYR 8
            QFQMYR
Sbjct: 2309 QFQMYR 2314
>XP_006715460
          Length = 2465

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    QFQMYR 8
            QFQMYR
Sbjct: 2318 QFQMYR 2323
>XP_006715459
          Length = 2475

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    QFQMYR 8
            QFQMYR
Sbjct: 2308 QFQMYR 2313
>XP_006715458
          Length = 2476

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    QFQMYR 8
            QFQMYR
Sbjct: 2309 QFQMYR 2314
>XP_006715457
          Length = 2485

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    QFQMYR 8
            QFQMYR
Sbjct: 2318 QFQMYR 2323
>XP_006715456
          Length = 2485

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    QFQMYR 8
            QFQMYR
Sbjct: 2318 QFQMYR 2323
>XP_005264018
          Length = 700

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAQFQMYRT 9
           SAQF M++T
Sbjct: 372 SAQFSMFQT 380
>XP_005264017
          Length = 786

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAQFQMYRT 9
           SAQF M++T
Sbjct: 458 SAQFSMFQT 466
>XP_005264016
          Length = 835

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAQFQMYRT 9
           SAQF M++T
Sbjct: 561 SAQFSMFQT 569
>XP_005264015
          Length = 838

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAQFQMYRT 9
           SAQF M++T
Sbjct: 510 SAQFSMFQT 518
>XP_005264014
          Length = 851

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAQFQMYRT 9
           SAQF M++T
Sbjct: 523 SAQFSMFQT 531
>XP_005264012
          Length = 854

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAQFQMYRT 9
           SAQF M++T
Sbjct: 526 SAQFSMFQT 534
>XP_005264011
          Length = 888

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAQFQMYRT 9
           SAQF M++T
Sbjct: 561 SAQFSMFQT 569
>XP_005264010
          Length = 889

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAQFQMYRT 9
           SAQF M++T
Sbjct: 561 SAQFSMFQT 569
>NP_060606
          Length = 3477

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    AQFQMYRT 9
            A F+MYRT
Sbjct: 2489 ATFRMYRT 2496
>NP_001229285
          Length = 209

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SAQFQMYRT 9
          SAQ QMY T
Sbjct: 20 SAQQQMYDT 28
>NP_001229286
          Length = 192

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SAQFQMYRT 9
          SAQ QMY T
Sbjct: 20 SAQQQMYDT 28
>NP_001137531
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SAQFQMYR 8
           SA+FQ Y+
Sbjct: 250 SAEFQWYK 257
>NP_001137530
          Length = 355

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SAQFQMYR 8
           SA+FQ Y+
Sbjct: 250 SAEFQWYK 257
>NP_057606
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SAQFQMYR 8
           SA+FQ Y+
Sbjct: 250 SAEFQWYK 257
>NP_001041674
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SAQFQMYR 8
           SA+FQ Y+
Sbjct: 250 SAEFQWYK 257
>XP_006718920
          Length = 303

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SAQFQMYR 8
           SA+FQ Y+
Sbjct: 209 SAEFQWYK 216
>XP_006718919
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SAQFQMYR 8
           SA+FQ Y+
Sbjct: 209 SAEFQWYK 216
>XP_006718918
          Length = 346

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SAQFQMYR 8
           SA+FQ Y+
Sbjct: 241 SAEFQWYK 248
>XP_005271639
          Length = 355

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SAQFQMYR 8
           SA+FQ Y+
Sbjct: 250 SAEFQWYK 257
>XP_006718917
          Length = 358

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SAQFQMYR 8
           SA+FQ Y+
Sbjct: 241 SAEFQWYK 248
>XP_005271637
          Length = 367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SAQFQMYR 8
           SA+FQ Y+
Sbjct: 250 SAEFQWYK 257
>XP_005271638
          Length = 367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SAQFQMYR 8
           SA+FQ Y+
Sbjct: 250 SAEFQWYK 257
>XP_006710019
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SAQFQMYR 8
           SA+FQ Y+
Sbjct: 448 SAEFQWYK 455
>NP_004381
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   FQMYRT 9
           F MYRT
Sbjct: 259 FMMYRT 264
>NP_115640
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   AQFQMYRT 9
           A FQ YR+
Sbjct: 586 ASFQQYRS 593
>NP_001243345
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   AQFQMYRT 9
           A FQ YR+
Sbjct: 574 ASFQQYRS 581
>NP_001243346
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   AQFQMYRT 9
           A FQ YR+
Sbjct: 516 ASFQQYRS 523
>NP_055592
          Length = 1524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQFQMYR 8
           AQF+ YR
Sbjct: 385 AQFRFYR 391
>NP_817123
          Length = 1040

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SAQFQMYRT 9
           ++QFQM+ T
Sbjct: 362 ASQFQMHPT 370
>XP_005254238
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   FQMYRT 9
           F MYRT
Sbjct: 221 FMMYRT 226
>XP_005273417
          Length = 1487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQFQMYR 8
           AQF+ YR
Sbjct: 385 AQFRFYR 391
>XP_006711022
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   AQFQMYRT 9
           A FQ YR+
Sbjct: 530 ASFQQYRS 537
>XP_006711021
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   AQFQMYRT 9
           A FQ YR+
Sbjct: 530 ASFQQYRS 537
>XP_006711020
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   AQFQMYRT 9
           A FQ YR+
Sbjct: 549 ASFQQYRS 556
>NP_001127925
          Length = 1059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SAQFQMYRT 9
           ++QFQM+ T
Sbjct: 362 ASQFQMHPT 370
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.122    0.339 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 390,963
Number of extensions: 574
Number of successful extensions: 48
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 48
Number of HSP's successfully gapped: 48
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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