Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004963                                                              19     869
XP_005251512                                                           19     869
NP_036222                                                              16    7355
XP_006712115                                                           16    7355
XP_006710603                                                           16    7355
XP_006710602                                                           16    7355
XP_006710601                                                           16    7355
XP_006710600                                                           16    7355
XP_005270757                                                           16    7355
XP_006710599                                                           16    7355
XP_006710598                                                           16    7355
XP_006710597                                                           16    7355
XP_006710596                                                           16    7355
XP_006710595                                                           16    7355
XP_006710594                                                           16    7355
XP_006710593                                                           16    7355
XP_006710592                                                           16    7355
XP_006710591                                                           16    7355
XP_006710590                                                           16    7355
XP_006710589                                                           16    7355
XP_006710588                                                           16    7355
XP_006710587                                                           16    7355
XP_006710586                                                           16    7355
XP_006710585                                                           16    7355
XP_005270755                                                           16    7355
XP_006710584                                                           16    7355
XP_005270754                                                           16    7355
XP_005270753                                                           16    7355
XP_006710583                                                           16    7355
XP_005270752                                                           16    7355
XP_006710582                                                           16    7355
XP_005270751                                                           16    7355
NP_064507                                                              16    7355
NP_001166126                                                           15    9605
NP_060730                                                              15    9605
NP_001073351                                                           15    9605
NP_001073350                                                           15    9605
NP_001073349                                                           15    9605
NP_057541                                                              15    9605
XP_005258773                                                           15    9605
>NP_004963
          Length = 1132

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  ALMSETER 9
          ALMSETER
Sbjct: 86 ALMSETER 93
>XP_005251512
          Length = 1132

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  ALMSETER 9
          ALMSETER
Sbjct: 86 ALMSETER 93
>NP_036222
          Length = 5430

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 1663 SALQQETEK 1671
>XP_006712115
          Length = 389

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   MSETER 9
           MSETER
Sbjct: 309 MSETER 314
>XP_006710603
          Length = 5324

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 1663 SALQQETEK 1671
>XP_006710602
          Length = 7391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3730 SALQQETEK 3738
>XP_006710601
          Length = 4720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3890 SALQQETEK 3898
>XP_006710600
          Length = 5384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 1663 SALQQETEK 1671
>XP_005270757
          Length = 5460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 1823 SALQQETEK 1831
>XP_006710599
          Length = 5656

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 1823 SALQQETEK 1831
>XP_006710598
          Length = 7553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3720 SALQQETEK 3728
>XP_006710597
          Length = 7451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3730 SALQQETEK 3738
>XP_006710596
          Length = 7512

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3679 SALQQETEK 3687
>XP_006710595
          Length = 7526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3693 SALQQETEK 3701
>XP_006710594
          Length = 7528

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3695 SALQQETEK 3703
>XP_006710593
          Length = 7539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3706 SALQQETEK 3714
>XP_006710592
          Length = 7544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3711 SALQQETEK 3719
>XP_006710591
          Length = 7558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3725 SALQQETEK 3733
>XP_006710590
          Length = 7563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3730 SALQQETEK 3738
>XP_006710589
          Length = 7595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3762 SALQQETEK 3770
>XP_006710588
          Length = 7614

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3890 SALQQETEK 3898
>XP_006710587
          Length = 7645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3812 SALQQETEK 3820
>XP_006710586
          Length = 7645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3890 SALQQETEK 3898
>XP_006710585
          Length = 7657

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3890 SALQQETEK 3898
>XP_005270755
          Length = 7663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3890 SALQQETEK 3898
>XP_006710584
          Length = 7686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3890 SALQQETEK 3898
>XP_005270754
          Length = 7694

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3890 SALQQETEK 3898
>XP_005270753
          Length = 7700

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3890 SALQQETEK 3898
>XP_006710583
          Length = 7702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3890 SALQQETEK 3898
>XP_005270752
          Length = 7717

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3890 SALQQETEK 3898
>XP_006710582
          Length = 7720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3890 SALQQETEK 3898
>XP_005270751
          Length = 7723

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SALMSETER 9
            SAL  ETE+
Sbjct: 3890 SALQQETEK 3898
>NP_064507
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   MSETER 9
           MSETER
Sbjct: 301 MSETER 306
>NP_001166126
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LMSETER 9
           LMS TER
Sbjct: 185 LMSSTER 191
>NP_060730
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LMSETER 9
           LMS TER
Sbjct: 119 LMSSTER 125
>NP_001073351
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SALMSETE 8
           SALM E+E
Sbjct: 181 SALMDESE 188
>NP_001073350
          Length = 878

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SALMSETE 8
           SALM E+E
Sbjct: 338 SALMDESE 345
>NP_001073349
          Length = 878

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SALMSETE 8
           SALM E+E
Sbjct: 338 SALMDESE 345
>NP_057541
          Length = 878

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SALMSETE 8
           SALM E+E
Sbjct: 338 SALMDESE 345
>XP_005258773
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SALMSETE 8
           SALM E+E
Sbjct: 181 SALMDESE 188
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.294    0.103    0.223 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 293,605
Number of extensions: 271
Number of successful extensions: 40
Number of sequences better than 10000.0: 40
Number of HSP's gapped: 40
Number of HSP's successfully gapped: 40
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package