Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              18    1482
NP_055572                                                              17    4312
NP_055620                                                              16    5631
NP_061187                                                              16    5631
NP_056448                                                              16    7355
NP_001165358                                                           16    7355
NP_001165359                                                           16    7355
XP_005257362                                                           16    7355
NP_861455                                                              16    7355
NP_001460                                                              15    9605
NP_001275906                                                           15    9605
NP_001275905                                                           15    9605
NP_001275907                                                           15    9605
NP_055573                                                              15    9605
NP_060033                                                              15    9605
NP_057554                                                              15    9605
NP_001092284                                                           15    9605
NP_079406                                                              15    9605
XP_006723866                                                           15    9605
XP_005260482                                                           15    9605
XP_005260481                                                           15    9605
XP_005271606                                                           15    9605
XP_005271605                                                           15    9605
XP_005271603                                                           15    9605
XP_005271602                                                           15    9605
XP_006713272                                                           15    9605
XP_005265295                                                           15    9605
>NP_115803
          Length = 1156

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  SAIVERLR 8
          SAIVERLR
Sbjct: 34 SAIVERLR 41
>NP_055572
          Length = 1016

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SAIVERLR 8
          SA++ERLR
Sbjct: 17 SAVMERLR 24
>NP_055620
          Length = 607

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SAIVERLR 8
          +A+VERLR
Sbjct: 75 AALVERLR 82
>NP_061187
          Length = 1133

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SAIVERLR 8
          S +VERLR
Sbjct: 71 STVVERLR 78
>NP_056448
          Length = 253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  AIVERLR 8
          A+VERLR
Sbjct: 14 ALVERLR 20
>NP_001165358
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  AIVERLR 8
          A+VERLR
Sbjct: 14 ALVERLR 20
>NP_001165359
          Length = 172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  AIVERLR 8
          A+VERLR
Sbjct: 14 ALVERLR 20
>XP_005257362
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SAIVERLR 8
           SAI+ RLR
Sbjct: 246 SAIIHRLR 253
>NP_861455
          Length = 462

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SAIVERLR 8
           SAI+ RLR
Sbjct: 334 SAIIHRLR 341
>NP_001460
          Length = 609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AIVERLR 8
           AIVE+LR
Sbjct: 464 AIVEKLR 470
>NP_001275906
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AIVERLR 8
           AIVE+LR
Sbjct: 423 AIVEKLR 429
>NP_001275905
          Length = 609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AIVERLR 8
           AIVE+LR
Sbjct: 464 AIVEKLR 470
>NP_001275907
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AIVERLR 8
           AIVE+LR
Sbjct: 414 AIVEKLR 420
>NP_055573
          Length = 992

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAIVERLRT 9
           SAIV+ L+T
Sbjct: 682 SAIVDTLKT 690
>NP_060033
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SAIVERLR 8
           SAI E+LR
Sbjct: 455 SAIAEKLR 462
>NP_057554
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AIVERLRT 9
           A+VE LRT
Sbjct: 145 AVVEPLRT 152
>NP_001092284
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SAIVERLR 8
          SA+++RLR
Sbjct: 54 SAVLQRLR 61
>NP_079406
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VERLRT 9
           VERLRT
Sbjct: 403 VERLRT 408
>XP_006723866
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AIVERLRT 9
           A+VE LRT
Sbjct: 145 AVVEPLRT 152
>XP_005260482
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AIVERLRT 9
           A+VE LRT
Sbjct: 145 AVVEPLRT 152
>XP_005260481
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AIVERLRT 9
           A+VE LRT
Sbjct: 145 AVVEPLRT 152
>XP_005271606
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SAIVERLRT 9
          SAIV+ L+T
Sbjct: 62 SAIVDTLKT 70
>XP_005271605
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAIVERLRT 9
           SAIV+ L+T
Sbjct: 107 SAIVDTLKT 115
>XP_005271603
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAIVERLRT 9
           SAIV+ L+T
Sbjct: 682 SAIVDTLKT 690
>XP_005271602
          Length = 915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAIVERLRT 9
           SAIV+ L+T
Sbjct: 682 SAIVDTLKT 690
>XP_006713272
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SAIVERLR 8
           SAI E+LR
Sbjct: 311 SAIAEKLR 318
>XP_005265295
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SAIVERLR 8
           SAI E+LR
Sbjct: 427 SAIAEKLR 434
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.131    0.306 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 389,832
Number of extensions: 537
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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