Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           19     665
NP_004561                                                              19     665
NP_001275703                                                           19     665
XP_005253450                                                           19     665
XP_006719151                                                           19     665
NP_055174                                                              17    3301
NP_055365                                                              17    4312
NP_059346                                                              16    5631
NP_001032405                                                           16    5631
NP_059348                                                              16    5631
NP_004593                                                              16    5631
NP_059347                                                              16    5631
XP_005260586                                                           16    5631
XP_005260585                                                           16    5631
XP_005260584                                                           16    5631
XP_005260583                                                           16    5631
XP_005260582                                                           16    5631
XP_006723932                                                           16    5631
XP_006723931                                                           16    5631
XP_006723930                                                           16    5631
XP_006723929                                                           16    5631
XP_005260581                                                           16    5631
XP_006723928                                                           16    5631
NP_068370                                                              16    7355
NP_001129631                                                           16    7355
NP_001129630                                                           16    7355
NP_001129629                                                           16    7355
NP_060072                                                              16    7355
XP_005278099                                                           16    7355
XP_005272679                                                           16    7355
XP_006724600                                                           16    7355
XP_005278096                                                           16    7355
NP_000089                                                              15    9605
NP_000121                                                              15    9605
NP_444283                                                              15    9605
NP_065910                                                              15    9605
NP_003584                                                              15    9605
XP_005258103                                                           15    9605
XP_006717768                                                           15    9605
XP_006717767                                                           15    9605
XP_005271861                                                           15    9605
XP_005263222                                                           15    9605
XP_005263221                                                           15    9605
XP_005263220                                                           15    9605
XP_006714345                                                           15    9605
XP_005263219                                                           15    9605
XP_005270541                                                           15    9605
NP_001092142                                                           15    9605
NP_001269795                                                           15    9605
>NP_001275701
          Length = 1486

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SAINPAKST 9
            SAI+PAKST
Sbjct: 1221 SAISPAKST 1229
>NP_004561
          Length = 1445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SAINPAKST 9
            SAI+PAKST
Sbjct: 1180 SAISPAKST 1188
>NP_001275703
          Length = 1264

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SAINPAKST 9
            SAI+PAKST
Sbjct: 999  SAISPAKST 1007
>XP_005253450
          Length = 1486

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SAINPAKST 9
            SAI+PAKST
Sbjct: 1221 SAISPAKST 1229
>XP_006719151
          Length = 1486

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SAINPAKST 9
            SAI+PAKST
Sbjct: 1221 SAISPAKST 1229
>NP_055174
          Length = 332

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  SAINPAKST 9
          ++I+PAKST
Sbjct: 87 TSISPAKST 95
>NP_055365
          Length = 1032

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  AINPAKST 9
          A+NPAK T
Sbjct: 41 ALNPAKLT 48
>NP_059346
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 361 AAPNPAKAT 369
>NP_001032405
          Length = 502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 367 AAPNPAKAT 375
>NP_059348
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 361 AAPNPAKAT 369
>NP_004593
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 361 AAPNPAKAT 369
>NP_059347
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 442 AAPNPAKAT 450
>XP_005260586
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 361 AAPNPAKAT 369
>XP_005260585
          Length = 502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 367 AAPNPAKAT 375
>XP_005260584
          Length = 502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 367 AAPNPAKAT 375
>XP_005260583
          Length = 502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 367 AAPNPAKAT 375
>XP_005260582
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 407 AAPNPAKAT 415
>XP_006723932
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 407 AAPNPAKAT 415
>XP_006723931
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 407 AAPNPAKAT 415
>XP_006723930
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 442 AAPNPAKAT 450
>XP_006723929
          Length = 583

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 448 AAPNPAKAT 456
>XP_005260581
          Length = 583

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 448 AAPNPAKAT 456
>XP_006723928
          Length = 583

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           +A NPAK+T
Sbjct: 448 AAPNPAKAT 456
>NP_068370
          Length = 614

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SAINPAKST 9
           S ++P+KST
Sbjct: 111 SRVSPSKST 119
>NP_001129631
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAINPAKST 9
           S +NP K+T
Sbjct: 115 SVVNPNKAT 123
>NP_001129630
          Length = 566

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAINPAKST 9
           S +NP K+T
Sbjct: 332 SVVNPNKAT 340
>NP_001129629
          Length = 566

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAINPAKST 9
           S +NP K+T
Sbjct: 332 SVVNPNKAT 340
>NP_060072
          Length = 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAINPAKST 9
           S +NP K+T
Sbjct: 337 SVVNPNKAT 345
>XP_005278099
          Length = 355

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAINPAKST 9
           S +NP K+T
Sbjct: 120 SVVNPNKAT 128
>XP_005272679
          Length = 567

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAINPAKST 9
           S +NP K+T
Sbjct: 332 SVVNPNKAT 340
>XP_006724600
          Length = 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAINPAKST 9
           S +NP K+T
Sbjct: 337 SVVNPNKAT 345
>XP_005278096
          Length = 572

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAINPAKST 9
           S +NP K+T
Sbjct: 337 SVVNPNKAT 345
>NP_000089
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   INPAKS 8
           +NPAKS
Sbjct: 178 LNPAKS 183
>NP_000121
          Length = 2224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    SAINPAK 7
            SA+NP K
Sbjct: 1732 SAVNPEK 1738
>NP_444283
          Length = 240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   INPAKS 8
           +NPAKS
Sbjct: 233 LNPAKS 238
>NP_065910
          Length = 1996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   INPAKST 9
           ++PAKST
Sbjct: 237 LSPAKST 243
>NP_003584
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   AINPAK 7
           A+NPAK
Sbjct: 347 ALNPAK 352
>XP_005258103
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   AINPAK 7
           A+NPAK
Sbjct: 347 ALNPAK 352
>XP_006717768
          Length = 573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AINPAKST 9
           A+ PAK+T
Sbjct: 139 ALKPAKNT 146
>XP_006717767
          Length = 573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AINPAKST 9
           A+ PAK+T
Sbjct: 139 ALKPAKNT 146
>XP_005271861
          Length = 573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AINPAKST 9
           A+ PAK+T
Sbjct: 139 ALKPAKNT 146
>XP_005263222
          Length = 1820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  INPAKST 9
          ++PAKST
Sbjct: 61 LSPAKST 67
>XP_005263221
          Length = 1820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  INPAKST 9
          ++PAKST
Sbjct: 61 LSPAKST 67
>XP_005263220
          Length = 1820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  INPAKST 9
          ++PAKST
Sbjct: 61 LSPAKST 67
>XP_006714345
          Length = 1961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   INPAKST 9
           ++PAKST
Sbjct: 202 LSPAKST 208
>XP_005263219
          Length = 1996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   INPAKST 9
           ++PAKST
Sbjct: 237 LSPAKST 243
>XP_005270541
          Length = 635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   INPAKS 8
           +NPAKS
Sbjct: 178 LNPAKS 183
>NP_001092142
          Length = 1159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAINPAKST 9
           SA++P K T
Sbjct: 542 SAVDPIKDT 550
>NP_001269795
          Length = 573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AINPAKST 9
           A+ PAK+T
Sbjct: 139 ALKPAKNT 146
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.291    0.102    0.253 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 618,566
Number of extensions: 500
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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