Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              18    1135
NP_008922                                                              17    2528
NP_001020026                                                           17    2528
NP_722576                                                              17    2528
XP_005262424                                                           17    2528
XP_006712978                                                           17    2528
XP_005264840                                                           17    2528
NP_066918                                                              17    3301
XP_006712194                                                           17    3301
XP_006712193                                                           17    3301
XP_006712192                                                           17    3301
XP_006712191                                                           17    3301
NP_859529                                                              17    4312
NP_001182684                                                           17    4312
NP_002302                                                              17    4312
NP_039269                                                              17    4312
NP_733752                                                              17    4312
XP_006721959                                                           17    4312
XP_005258028                                                           17    4312
XP_005258027                                                           17    4312
NP_937847                                                              17    4312
NP_937848                                                              17    4312
NP_001139150                                                           16    5631
XP_006721232                                                           16    5631
XP_005255893                                                           16    5631
XP_006714651                                                           16    5631
NP_722579                                                              16    5631
NP_001018048                                                           16    7355
NP_056001                                                              16    7355
NP_001018047                                                           16    7355
NP_150648                                                              16    7355
NP_073577                                                              16    7355
NP_001106710                                                           16    7355
NP_852003                                                              16    7355
NP_938010                                                              16    7355
NP_938009                                                              16    7355
NP_689909                                                              16    7355
NP_001028774                                                           16    7355
XP_006715999                                                           16    7355
XP_006715998                                                           16    7355
XP_006715997                                                           16    7355
XP_005270670                                                           16    7355
XP_005270669                                                           16    7355
XP_006710506                                                           16    7355
XP_005270668                                                           16    7355
XP_005270667                                                           16    7355
XP_005270666                                                           16    7355
NP_003814                                                              15    9605
NP_001011544                                                           15    9605
NP_005357                                                              15    9605
NP_001240841                                                           15    9605
NP_055988                                                              15    9605
NP_004542                                                              15    9605
NP_001269376                                                           15    9605
NP_079496                                                              15    9605
XP_006723705                                                           15    9605
XP_006723704                                                           15    9605
XP_006723703                                                           15    9605
XP_006723702                                                           15    9605
XP_005260900                                                           15    9605
XP_006723701                                                           15    9605
XP_006723700                                                           15    9605
XP_006723699                                                           15    9605
XP_006723698                                                           15    9605
XP_006723697                                                           15    9605
XP_006723696                                                           15    9605
XP_006723695                                                           15    9605
XP_005262708                                                           15    9605
XP_005262706                                                           15    9605
XP_006714063                                                           15    9605
XP_005262705                                                           15    9605
XP_006714062                                                           15    9605
XP_005262704                                                           15    9605
XP_005262703                                                           15    9605
>NP_004251
          Length = 1208

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   SAFQEVSI 8
           SAFQEVSI
Sbjct: 240 SAFQEVSI 247
>NP_008922
          Length = 1029

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FQEVSIC 9
           F+EVS+C
Sbjct: 219 FEEVSVC 225
>NP_001020026
          Length = 267

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FQEVSIC 9
           F+EVS+C
Sbjct: 219 FEEVSVC 225
>NP_722576
          Length = 3080

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SAFQEVSIC 9
            S+FQ+V +C
Sbjct: 2801 SSFQKVGVC 2809
>XP_005262424
          Length = 2875

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SAFQEVSIC 9
            S+FQ+V +C
Sbjct: 2596 SSFQKVGVC 2604
>XP_006712978
          Length = 826

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  FQEVSIC 9
          F+EVS+C
Sbjct: 16 FEEVSVC 22
>XP_005264840
          Length = 1029

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FQEVSIC 9
           F+EVS+C
Sbjct: 219 FEEVSVC 225
>NP_066918
          Length = 635

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FQEVSIC 9
           FQ+VS+C
Sbjct: 300 FQQVSLC 306
>XP_006712194
          Length = 362

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FQEVSIC 9
           FQ+VS+C
Sbjct: 300 FQQVSLC 306
>XP_006712193
          Length = 635

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FQEVSIC 9
           FQ+VS+C
Sbjct: 300 FQQVSLC 306
>XP_006712192
          Length = 635

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FQEVSIC 9
           FQ+VS+C
Sbjct: 300 FQQVSLC 306
>XP_006712191
          Length = 635

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FQEVSIC 9
           FQ+VS+C
Sbjct: 300 FQQVSLC 306
>NP_859529
          Length = 377

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AFQEVSIC 9
           A QE+SIC
Sbjct: 187 ADQEISIC 194
>NP_001182684
          Length = 361

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AFQEVSIC 9
           A QE+SIC
Sbjct: 187 ADQEISIC 194
>NP_002302
          Length = 949

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SAFQEVSIC 9
           +AFQ+ ++C
Sbjct: 583 AAFQDANVC 591
>NP_039269
          Length = 1009

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SAFQEVSIC 9
           +AFQ+ ++C
Sbjct: 583 AAFQDANVC 591
>NP_733752
          Length = 298

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SAFQEVSIC 9
           ++FQE+S C
Sbjct: 260 ASFQELSAC 268
>XP_006721959
          Length = 958

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SAFQEVSIC 9
           +AFQ+ ++C
Sbjct: 592 AAFQDANVC 600
>XP_005258028
          Length = 1009

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SAFQEVSIC 9
           +AFQ+ ++C
Sbjct: 583 AAFQDANVC 591
>XP_005258027
          Length = 1018

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SAFQEVSIC 9
           +AFQ+ ++C
Sbjct: 592 AAFQDANVC 600
>NP_937847
          Length = 244

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SAFQEVSIC 9
           ++FQE+S C
Sbjct: 206 ASFQELSAC 214
>NP_937848
          Length = 214

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SAFQEVSIC 9
           ++FQE+S C
Sbjct: 176 ASFQELSAC 184
>NP_001139150
          Length = 1275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SAFQEVSI 8
           SAF+EVS+
Sbjct: 419 SAFKEVSL 426
>XP_006721232
          Length = 528

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           + FQ +SIC
Sbjct: 396 TGFQNMSIC 404
>XP_005255893
          Length = 528

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           + FQ +SIC
Sbjct: 396 TGFQNMSIC 404
>XP_006714651
          Length = 1280

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SAFQEVSI 8
           SAF+EVS+
Sbjct: 419 SAFKEVSL 426
>NP_722579
          Length = 528

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           + FQ +SIC
Sbjct: 396 TGFQNMSIC 404
>NP_001018048
          Length = 3069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SAFQEVSIC 9
            + FQE+ IC
Sbjct: 1500 AVFQEMYIC 1508
>NP_056001
          Length = 3095

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SAFQEVSIC 9
            + FQE+ IC
Sbjct: 1500 AVFQEMYIC 1508
>NP_001018047
          Length = 3135

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SAFQEVSIC 9
            + FQE+ IC
Sbjct: 1461 AVFQEMYIC 1469
>NP_150648
          Length = 3174

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SAFQEVSIC 9
            + FQE+ IC
Sbjct: 1500 AVFQEMYIC 1508
>NP_073577
          Length = 1198

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SAFQEVSIC 9
           S FQ + IC
Sbjct: 543 SCFQNMEIC 551
>NP_001106710
          Length = 1171

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SAFQEVSIC 9
           S FQ + IC
Sbjct: 543 SCFQNMEIC 551
>NP_852003
          Length = 816

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SAFQEVSIC 9
           S FQ + IC
Sbjct: 140 SCFQNMEIC 148
>NP_938010
          Length = 836

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SAFQEVSIC 9
           S FQ + IC
Sbjct: 160 SCFQNMEIC 168
>NP_938009
          Length = 1210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SAFQEVSIC 9
           S FQ + IC
Sbjct: 534 SCFQNMEIC 542
>NP_689909
          Length = 1075

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SAFQEVSIC 9
           S FQ + IC
Sbjct: 534 SCFQNMEIC 542
>NP_001028774
          Length = 1379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SAFQEVSI 8
           S+FQ+VS+
Sbjct: 563 SSFQDVSV 570
>XP_006715999
          Length = 1170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SAFQEVSIC 9
           S FQ + IC
Sbjct: 543 SCFQNMEIC 551
>XP_006715998
          Length = 1191

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SAFQEVSIC 9
           S FQ + IC
Sbjct: 536 SCFQNMEIC 544
>XP_006715997
          Length = 1197

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SAFQEVSIC 9
           S FQ + IC
Sbjct: 543 SCFQNMEIC 551
>XP_005270670
          Length = 1210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SAFQEVSIC 9
           S FQ + IC
Sbjct: 534 SCFQNMEIC 542
>XP_005270669
          Length = 1210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SAFQEVSIC 9
           S FQ + IC
Sbjct: 534 SCFQNMEIC 542
>XP_006710506
          Length = 1247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SAFQEVSIC 9
           S FQ + IC
Sbjct: 605 SCFQNMEIC 613
>XP_005270668
          Length = 1256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SAFQEVSIC 9
           S FQ + IC
Sbjct: 605 SCFQNMEIC 613
>XP_005270667
          Length = 1280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SAFQEVSIC 9
           S FQ + IC
Sbjct: 605 SCFQNMEIC 613
>XP_005270666
          Length = 1281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SAFQEVSIC 9
           S FQ + IC
Sbjct: 605 SCFQNMEIC 613
>NP_003814
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AFQEVSI 8
           AFQ++SI
Sbjct: 220 AFQDISI 226
>NP_001011544
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   FQEVSIC 9
           F+E S+C
Sbjct: 235 FREASVC 241
>NP_005357
          Length = 429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   FQEVSIC 9
           F+E S+C
Sbjct: 264 FREASVC 270
>NP_001240841
          Length = 1159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   FQEVSIC 9
           F+E+S C
Sbjct: 316 FKEISFC 322
>NP_055988
          Length = 1168

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   FQEVSIC 9
           F+E+S C
Sbjct: 316 FKEISFC 322
>NP_004542
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1  SAFQEVSIC 9
          S F E+ +C
Sbjct: 79 SCFNELEVC 87
>NP_001269376
          Length = 812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           +AFQE+  C
Sbjct: 645 NAFQELQRC 653
>NP_079496
          Length = 813

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           +AFQE+  C
Sbjct: 645 NAFQELQRC 653
>XP_006723705
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           +AFQE+  C
Sbjct: 567 NAFQELQRC 575
>XP_006723704
          Length = 742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           +AFQE+  C
Sbjct: 574 NAFQELQRC 582
>XP_006723703
          Length = 823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           +AFQE+  C
Sbjct: 655 NAFQELQRC 663
>XP_006723702
          Length = 825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           +AFQE+  C
Sbjct: 658 NAFQELQRC 666
>XP_005260900
          Length = 826

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           +AFQE+  C
Sbjct: 658 NAFQELQRC 666
>XP_006723701
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           +AFQE+  C
Sbjct: 695 NAFQELQRC 703
>XP_006723700
          Length = 869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           +AFQE+  C
Sbjct: 701 NAFQELQRC 709
>XP_006723699
          Length = 870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           +AFQE+  C
Sbjct: 702 NAFQELQRC 710
>XP_006723698
          Length = 876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           +AFQE+  C
Sbjct: 708 NAFQELQRC 716
>XP_006723697
          Length = 882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           +AFQE+  C
Sbjct: 714 NAFQELQRC 722
>XP_006723696
          Length = 882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           +AFQE+  C
Sbjct: 715 NAFQELQRC 723
>XP_006723695
          Length = 883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SAFQEVSIC 9
           +AFQE+  C
Sbjct: 715 NAFQELQRC 723
>XP_005262708
          Length = 1039

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   FQEVSIC 9
           F+E+S C
Sbjct: 187 FKEISFC 193
>XP_005262706
          Length = 1146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   FQEVSIC 9
           F+E+S C
Sbjct: 187 FKEISFC 193
>XP_006714063
          Length = 1168

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   FQEVSIC 9
           F+E+S C
Sbjct: 316 FKEISFC 322
>XP_005262705
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   FQEVSIC 9
           F+E+S C
Sbjct: 316 FKEISFC 322
>XP_006714062
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   FQEVSIC 9
           F+E+S C
Sbjct: 316 FKEISFC 322
>XP_005262704
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   FQEVSIC 9
           F+E+S C
Sbjct: 316 FKEISFC 322
>XP_005262703
          Length = 1275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   FQEVSIC 9
           F+E+S C
Sbjct: 316 FKEISFC 322
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.127    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 496,493
Number of extensions: 996
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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