Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055455                                                              17    2528
XP_006712938                                                           17    2528
XP_006712937                                                           17    2528
XP_006712936                                                           17    2528
XP_005247034                                                           17    2528
NP_054888                                                              17    3301
NP_997716                                                              17    4312
NP_001130015                                                           17    4312
NP_055568                                                              16    5631
XP_005271905                                                           16    5631
XP_005271904                                                           16    5631
XP_005271903                                                           16    5631
NP_003613                                                              16    7355
NP_001185845                                                           16    7355
NP_803193                                                              16    7355
NP_001185844                                                           16    7355
XP_005266313                                                           16    7355
XP_006719224                                                           16    7355
XP_006719223                                                           16    7355
XP_006719222                                                           16    7355
XP_005253573                                                           16    7355
XP_005253572                                                           16    7355
XP_005253571                                                           16    7355
XP_005253568                                                           16    7355
XP_005253567                                                           16    7355
XP_005253566                                                           16    7355
XP_005253565                                                           16    7355
XP_005253564                                                           16    7355
XP_005253563                                                           16    7355
XP_005253562                                                           16    7355
NP_689538                                                              16    7355
NP_000436                                                              15    9605
NP_958780                                                              15    9605
NP_958781                                                              15    9605
NP_958785                                                              15    9605
NP_958783                                                              15    9605
NP_958786                                                              15    9605
NP_958782                                                              15    9605
NP_958784                                                              15    9605
XP_006716654                                                           15    9605
XP_005251041                                                           15    9605
XP_005251040                                                           15    9605
XP_006716653                                                           15    9605
XP_006716652                                                           15    9605
XP_005251039                                                           15    9605
XP_005251038                                                           15    9605
XP_005251036                                                           15    9605
XP_005251037                                                           15    9605
XP_005251035                                                           15    9605
XP_006716651                                                           15    9605
XP_005251034                                                           15    9605
XP_005251033                                                           15    9605
>NP_055455
          Length = 1199

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AQKMKKA 9
           AQKMKKA
Sbjct: 976 AQKMKKA 982
>XP_006712938
          Length = 1138

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AQKMKKA 9
           AQKMKKA
Sbjct: 976 AQKMKKA 982
>XP_006712937
          Length = 1199

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AQKMKKA 9
           AQKMKKA
Sbjct: 976 AQKMKKA 982
>XP_006712936
          Length = 1199

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AQKMKKA 9
           AQKMKKA
Sbjct: 976 AQKMKKA 982
>XP_005247034
          Length = 1199

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   AQKMKKA 9
           AQKMKKA
Sbjct: 976 AQKMKKA 982
>NP_054888
          Length = 265

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   AAQKMKKA 9
           AAQ MKKA
Sbjct: 152 AAQSMKKA 159
>NP_997716
          Length = 227

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SAAQKMKK 8
           +AAQK+KK
Sbjct: 171 AAAQKLKK 178
>NP_001130015
          Length = 179

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SAAQKMKK 8
           +AAQK+KK
Sbjct: 123 AAAQKLKK 130
>NP_055568
          Length = 1282

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQKMKKA 9
            +QKMKKA
Sbjct: 1219 SQKMKKA 1225
>XP_005271905
          Length = 1219

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQKMKKA 9
            +QKMKKA
Sbjct: 1156 SQKMKKA 1162
>XP_005271904
          Length = 1219

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQKMKKA 9
            +QKMKKA
Sbjct: 1156 SQKMKKA 1162
>XP_005271903
          Length = 1282

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AQKMKKA 9
            +QKMKKA
Sbjct: 1219 SQKMKKA 1225
>NP_003613
          Length = 1005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 286 QKMKKA 291
>NP_001185845
          Length = 980

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 275 QKMKKA 280
>NP_803193
          Length = 1011

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 306 QKMKKA 311
>NP_001185844
          Length = 858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 153 QKMKKA 158
>XP_005266313
          Length = 281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAAQKMKKA 9
           S AQK+KK+
Sbjct: 147 SKAQKIKKS 155
>XP_006719224
          Length = 991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 286 QKMKKA 291
>XP_006719223
          Length = 580

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 317 QKMKKA 322
>XP_006719222
          Length = 883

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 164 QKMKKA 169
>XP_005253573
          Length = 991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 275 QKMKKA 280
>XP_005253572
          Length = 994

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 275 QKMKKA 280
>XP_005253571
          Length = 1002

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 286 QKMKKA 291
>XP_005253568
          Length = 1014

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 306 QKMKKA 311
>XP_005253567
          Length = 1025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 317 QKMKKA 322
>XP_005253566
          Length = 1025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 306 QKMKKA 311
>XP_005253565
          Length = 1026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 317 QKMKKA 322
>XP_005253564
          Length = 1033

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 317 QKMKKA 322
>XP_005253563
          Length = 1036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 317 QKMKKA 322
>XP_005253562
          Length = 1036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QKMKKA 9
           QKMKKA
Sbjct: 317 QKMKKA 322
>NP_689538
          Length = 289

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SAAQKMKKA 9
           S AQK+KK+
Sbjct: 155 SKAQKIKKS 163
>NP_000436
          Length = 4574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4396 SAAQALKK 4403
>NP_958780
          Length = 4533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4355 SAAQALKK 4362
>NP_958781
          Length = 4525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4347 SAAQALKK 4354
>NP_958785
          Length = 4551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4373 SAAQALKK 4380
>NP_958783
          Length = 4515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4337 SAAQALKK 4344
>NP_958786
          Length = 4547

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4369 SAAQALKK 4376
>NP_958782
          Length = 4684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4506 SAAQALKK 4513
>NP_958784
          Length = 4547

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4369 SAAQALKK 4376
>XP_006716654
          Length = 3562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 3384 SAAQALKK 3391
>XP_005251041
          Length = 4520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4342 SAAQALKK 4349
>XP_005251040
          Length = 4524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4346 SAAQALKK 4353
>XP_006716653
          Length = 4529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4351 SAAQALKK 4358
>XP_006716652
          Length = 4529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4351 SAAQALKK 4358
>XP_005251039
          Length = 4530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4352 SAAQALKK 4359
>XP_005251038
          Length = 4538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4360 SAAQALKK 4367
>XP_005251036
          Length = 4552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4374 SAAQALKK 4381
>XP_005251037
          Length = 4552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4374 SAAQALKK 4381
>XP_005251035
          Length = 4556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4378 SAAQALKK 4385
>XP_006716651
          Length = 4579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4401 SAAQALKK 4408
>XP_005251034
          Length = 4685

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4507 SAAQALKK 4514
>XP_005251033
          Length = 4689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SAAQKMKK 8
            SAAQ +KK
Sbjct: 4511 SAAQALKK 4518
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.294   0.0938    0.202 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 343,971
Number of extensions: 530
Number of successful extensions: 52
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package