Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001277137                                                           17    4312
NP_001277138                                                           17    4312
NP_001121695                                                           17    4312
XP_005249810                                                           17    4312
XP_006712976                                                           17    4312
XP_006712975                                                           17    4312
XP_006712974                                                           17    4312
XP_005264770                                                           17    4312
XP_005264768                                                           17    4312
XP_005264767                                                           17    4312
XP_006712973                                                           17    4312
NP_000382                                                              16    5631
NP_597703                                                              16    5631
NP_001278308                                                           16    5631
NP_001263272                                                           16    5631
NP_848622                                                              16    5631
NP_003638                                                              16    5631
NP_001137472                                                           16    5631
NP_001177739                                                           16    5631
NP_001071153                                                           16    5631
XP_005276439                                                           16    5631
XP_005276438                                                           16    5631
XP_006726583                                                           16    5631
XP_005260237                                                           16    5631
XP_005257806                                                           16    5631
XP_006722206                                                           16    5631
XP_006718155                                                           16    5631
XP_005269898                                                           16    5631
XP_006717922                                                           16    5631
XP_006717921                                                           16    5631
XP_006717920                                                           16    5631
XP_005269897                                                           16    5631
XP_006717919                                                           16    5631
XP_006717918                                                           16    5631
XP_006717917                                                           16    5631
XP_006717916                                                           16    5631
XP_005269893                                                           16    5631
XP_006717685                                                           16    5631
XP_005271857                                                           16    5631
XP_006717684                                                           16    5631
XP_006717682                                                           16    5631
XP_005271854                                                           16    5631
NP_001071133                                                           16    5631
NP_056144                                                              16    7355
NP_114141                                                              16    7355
XP_006722774                                                           16    7355
XP_005259895                                                           16    7355
XP_005259894                                                           16    7355
NP_000668                                                              15    9605
NP_955806                                                              15    9605
NP_055247                                                              15    9605
NP_001265651                                                           15    9605
NP_001265653                                                           15    9605
NP_001265652                                                           15    9605
NP_955805                                                              15    9605
NP_955452                                                              15    9605
NP_714544                                                              15    9605
NP_065102                                                              15    9605
XP_006720470                                                           15    9605
XP_006715569                                                           15    9605
XP_006715568                                                           15    9605
XP_005247192                                                           15    9605
XP_006713543                                                           15    9605
XP_006710049                                                           15    9605
>NP_001277137
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   WSMVITN 8
           W +VITN
Sbjct: 113 WQIVITN 119
>NP_001277138
          Length = 864

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  WSMVITN 8
          W +VITN
Sbjct: 63 WQIVITN 69
>NP_001121695
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   WSMVITN 8
           W +VITN
Sbjct: 113 WQIVITN 119
>XP_005249810
          Length = 390

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   WSMVITNE 9
           W++V+T+E
Sbjct: 358 WALVLTSE 365
>XP_006712976
          Length = 635

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   WSMVITN 8
           W +VITN
Sbjct: 113 WQIVITN 119
>XP_006712975
          Length = 907

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   WSMVITN 8
           W +VITN
Sbjct: 106 WQIVITN 112
>XP_006712974
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   WSMVITN 8
           W +VITN
Sbjct: 113 WQIVITN 119
>XP_005264770
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   WSMVITN 8
           W +VITN
Sbjct: 113 WQIVITN 119
>XP_005264768
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   WSMVITN 8
           W +VITN
Sbjct: 113 WQIVITN 119
>XP_005264767
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   WSMVITN 8
           W +VITN
Sbjct: 113 WQIVITN 119
>XP_006712973
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   WSMVITN 8
           W +VITN
Sbjct: 113 WQIVITN 119
>NP_000382
          Length = 563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RWSMVITNE 9
           +W M+++NE
Sbjct: 306 QWLMLLSNE 314
>NP_597703
          Length = 663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 226 RWSNLFTSE 234
>NP_001278308
          Length = 578

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 141 RWSNLFTSE 149
>NP_001263272
          Length = 686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 249 RWSNLFTSE 257
>NP_848622
          Length = 1124

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RWSMVIT 7
           RW +VIT
Sbjct: 370 RWGVVIT 376
>NP_003638
          Length = 567

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RW + +TN+
Sbjct: 349 RWKVQVTNK 357
>NP_001137472
          Length = 686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 249 RWSNLFTSE 257
>NP_001177739
          Length = 658

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 249 RWSNLFTSE 257
>NP_001071153
          Length = 663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 226 RWSNLFTSE 234
>XP_005276439
          Length = 663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 226 RWSNLFTSE 234
>XP_005276438
          Length = 686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 249 RWSNLFTSE 257
>XP_006726583
          Length = 485

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  RWSMVITNE 9
          RWS + T+E
Sbjct: 48 RWSNLFTSE 56
>XP_005260237
          Length = 356

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2  WSMVITN 8
          WS ++TN
Sbjct: 29 WSSILTN 35
>XP_005257806
          Length = 409

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RW + +TN+
Sbjct: 349 RWKVQVTNK 357
>XP_006722206
          Length = 434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RW + +TN+
Sbjct: 349 RWKVQVTNK 357
>XP_006718155
          Length = 485

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  RWSMVITNE 9
          RWS + T+E
Sbjct: 48 RWSNLFTSE 56
>XP_005269898
          Length = 485

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  RWSMVITNE 9
          RWS + T+E
Sbjct: 48 RWSNLFTSE 56
>XP_006717922
          Length = 525

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  RWSMVITNE 9
          RWS + T+E
Sbjct: 88 RWSNLFTSE 96
>XP_006717921
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 210 RWSNLFTSE 218
>XP_006717920
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 210 RWSNLFTSE 218
>XP_005269897
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 210 RWSNLFTSE 218
>XP_006717919
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 210 RWSNLFTSE 218
>XP_006717918
          Length = 686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 249 RWSNLFTSE 257
>XP_006717917
          Length = 686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 249 RWSNLFTSE 257
>XP_006717916
          Length = 739

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 302 RWSNLFTSE 310
>XP_005269893
          Length = 739

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 302 RWSNLFTSE 310
>XP_006717685
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 210 RWSNLFTSE 218
>XP_005271857
          Length = 686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 249 RWSNLFTSE 257
>XP_006717684
          Length = 686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 249 RWSNLFTSE 257
>XP_006717682
          Length = 716

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 279 RWSNLFTSE 287
>XP_005271854
          Length = 739

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 302 RWSNLFTSE 310
>NP_001071133
          Length = 686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RWSMVITNE 9
           RWS + T+E
Sbjct: 249 RWSNLFTSE 257
>NP_056144
          Length = 613

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 2   WSMVITN 8
           W+ ++TN
Sbjct: 415 WAFIVTN 421
>NP_114141
          Length = 5635

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RWSMVITNE 9
            R+S V TNE
Sbjct: 2643 RYSCVATNE 2651
>XP_006722774
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 2   WSMVITN 8
           W+ ++TN
Sbjct: 454 WAFIVTN 460
>XP_005259895
          Length = 624

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 2   WSMVITN 8
           W+ ++TN
Sbjct: 426 WAFIVTN 432
>XP_005259894
          Length = 651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 2   WSMVITN 8
           W+ ++TN
Sbjct: 454 WAFIVTN 460
>NP_000668
          Length = 318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   WSMVITNE 9
           W+M +T+E
Sbjct: 149 WNMKLTSE 156
>NP_955806
          Length = 950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 2   WSMVI 6
           WSMVI
Sbjct: 884 WSMVI 888
>NP_055247
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 2   WSMVITN 8
           WS  +TN
Sbjct: 194 WSQCVTN 200
>NP_001265651
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 2   WSMVITN 8
           WS  +TN
Sbjct: 145 WSQCVTN 151
>NP_001265653
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 2  WSMVITN 8
          WS  +TN
Sbjct: 61 WSQCVTN 67
>NP_001265652
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 2  WSMVITN 8
          WS  +TN
Sbjct: 83 WSQCVTN 89
>NP_955805
          Length = 950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 2   WSMVI 6
           WSMVI
Sbjct: 884 WSMVI 888
>NP_955452
          Length = 2590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 7/8 (87%)

Query: 2    WSMVITNE 9
            W++ +TN+
Sbjct: 1124 WNITLTND 1131
>NP_714544
          Length = 1775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2    WSMVIT 7
            WS+V+T
Sbjct: 1762 WSLVLT 1767
>NP_065102
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 7/8 (87%)

Query: 2  WSMVITNE 9
          W ++++NE
Sbjct: 50 WEILVSNE 57
>XP_006720470
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2    WSMVIT 7
            WS+V+T
Sbjct: 1004 WSLVLT 1009
>XP_006715569
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 2  WSMVITN 8
          WS  +TN
Sbjct: 61 WSQCVTN 67
>XP_006715568
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 2   WSMVITN 8
           WS  +TN
Sbjct: 172 WSQCVTN 178
>XP_005247192
          Length = 961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 2   WSMVI 6
           WSMVI
Sbjct: 895 WSMVI 899
>XP_006713543
          Length = 2591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 7/8 (87%)

Query: 2    WSMVITNE 9
            W++ +TN+
Sbjct: 1125 WNITLTND 1132
>XP_006710049
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   WSMVIT 7
           WS+V+T
Sbjct: 280 WSLVLT 285
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.123    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 535,716
Number of extensions: 940
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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