Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              18    1482
XP_005266703                                                           18    1482
NP_056234                                                              17    3301
XP_005274542                                                           17    3301
NP_004360                                                              16    5631
NP_476508                                                              16    5631
NP_476507                                                              16    5631
NP_004148                                                              16    5631
XP_005265372                                                           16    5631
XP_005265371                                                           16    5631
XP_005265370                                                           16    5631
XP_005246123                                                           16    5631
XP_005246122                                                           16    5631
XP_006712316                                                           16    5631
NP_001165907                                                           16    7355
NP_002628                                                              16    7355
NP_001116142                                                           16    7355
NP_000947                                                              16    7355
NP_055535                                                              16    7355
XP_006724724                                                           16    7355
XP_005270358                                                           16    7355
NP_000597                                                              15    9605



>NP_443179
          Length = 2170

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    RVSVVAET 8
            RVSVVAET
Sbjct: 1192 RVSVVAET 1199





>XP_005266703
          Length = 1501

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RVSVVAET 8
           RVSVVAET
Sbjct: 523 RVSVVAET 530





>NP_056234
          Length = 2828

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    VSVVAETD 9
            VSV AETD
Sbjct: 1863 VSVTAETD 1870





>XP_005274542
          Length = 2853

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    VSVVAETD 9
            VSV AETD
Sbjct: 1888 VSVTAETD 1895





>NP_004360
          Length = 3177

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    RVSVVAET 8
            RVSVVA T
Sbjct: 1886 RVSVVANT 1893





>NP_476508
          Length = 2971

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    RVSVVAET 8
            RVSVVA T
Sbjct: 1680 RVSVVANT 1687





>NP_476507
          Length = 2570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    RVSVVAET 8
            RVSVVA T
Sbjct: 1279 RVSVVANT 1286





>NP_004148
          Length = 404

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RVSVVAET 8
           RVSV AET
Sbjct: 97  RVSVCAET 104





>XP_005265372
          Length = 330

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RVSVVAET 8
           RVSV AET
Sbjct: 97  RVSVCAET 104





>XP_005265371
          Length = 382

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RVSVVAET 8
           RVSV AET
Sbjct: 97  RVSVCAET 104





>XP_005265370
          Length = 404

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RVSVVAET 8
           RVSV AET
Sbjct: 97  RVSVCAET 104





>XP_005246123
          Length = 2770

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    RVSVVAET 8
            RVSVVA T
Sbjct: 1479 RVSVVANT 1486





>XP_005246122
          Length = 2977

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    RVSVVAET 8
            RVSVVA T
Sbjct: 1686 RVSVVANT 1693





>XP_006712316
          Length = 3010

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    RVSVVAET 8
            RVSVVA T
Sbjct: 1719 RVSVVANT 1726





>NP_001165907
          Length = 1151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RVSVVAETD 9
           +VS++AET+
Sbjct: 441 QVSILAETE 449





>NP_002628
          Length = 1223

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RVSVVAETD 9
           +VS++AET+
Sbjct: 441 QVSILAETE 449





>NP_001116142
          Length = 1210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RVSVVAETD 9
           +VS++AET+
Sbjct: 441 QVSILAETE 449





>NP_000947
          Length = 358

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RVSVVAETD 9
           RVS+  ETD
Sbjct: 253 RVSMAEETD 261





>NP_055535
          Length = 1235

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVVAETD 9
           SVVA+TD
Sbjct: 655 SVVADTD 661





>XP_006724724
          Length = 1164

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RVSVVAETD 9
           +VS++AET+
Sbjct: 441 QVSILAETE 449





>XP_005270358
          Length = 1204

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SVVAETD 9
           SVVA+TD
Sbjct: 655 SVVADTD 661





>NP_000597
          Length = 202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VVAETD 9
           VVAETD
Sbjct: 126 VVAETD 131





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.120    0.281 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 273,814
Number of extensions: 386
Number of successful extensions: 22
Number of sequences better than 10000.0: 22
Number of HSP's gapped: 22
Number of HSP's successfully gapped: 22
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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