Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              17    3301
XP_006714104                                                           17    3301
XP_005265800                                                           17    3301
XP_006714103                                                           17    3301
XP_006714102                                                           17    3301
NP_004326                                                              16    5631
NP_001191236                                                           16    7355
NP_001191235                                                           16    7355
NP_000574                                                              16    7355
NP_004435                                                              16    7355
NP_001008487                                                           16    7355
NP_001008486                                                           16    7355
NP_001008485                                                           16    7355
NP_060306                                                              16    7355
NP_001157947                                                           16    7355
XP_005271680                                                           16    7355
XP_005271679                                                           16    7355
XP_005271678                                                           16    7355
XP_005271676                                                           16    7355
XP_005271681                                                           16    7355
XP_006718955                                                           16    7355
XP_006718954                                                           16    7355
XP_006718953                                                           16    7355
XP_006718950                                                           16    7355
XP_005273894                                                           16    7355
XP_006714240                                                           16    7355
XP_005247622                                                           16    7355
XP_005247621                                                           16    7355
XP_006713744                                                           16    7355
XP_005247620                                                           16    7355
XP_005247619                                                           16    7355
XP_005247618                                                           16    7355
XP_005247617                                                           16    7355
XP_005247616                                                           16    7355
NP_878253                                                              16    7355
NP_006718                                                              15    9605
NP_001017922                                                           15    9605
NP_061008                                                              15    9605
NP_001152849                                                           15    9605
NP_001152850                                                           15    9605
NP_073601                                                              15    9605
NP_001152851                                                           15    9605
NP_001152852                                                           15    9605
NP_057363                                                              15    9605
XP_005256170                                                           15    9605
XP_005256156                                                           15    9605
XP_005256164                                                           15    9605
XP_005256158                                                           15    9605
XP_005256160                                                           15    9605
XP_005256157                                                           15    9605
XP_006710376                                                           15    9605
XP_005270472                                                           15    9605
>NP_006197
          Length = 1089

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLLVIV
Sbjct: 531 VLVLLVIV 538
>XP_006714104
          Length = 832

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLLVIV
Sbjct: 556 VLVLLVIV 563
>XP_005265800
          Length = 1089

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLLVIV
Sbjct: 531 VLVLLVIV 538
>XP_006714103
          Length = 1111

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLLVIV
Sbjct: 553 VLVLLVIV 560
>XP_006714102
          Length = 1114

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLLVIV
Sbjct: 556 VLVLLVIV 563
>NP_004326
          Length = 180

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  VLVLLVIV 9
          +LVLL+IV
Sbjct: 28 ILVLLIIV 35
>NP_001191236
          Length = 493

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RVLVLLVIV 9
          RVLVLL+ V
Sbjct: 22 RVLVLLLAV 30
>NP_001191235
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RVLVLLVIV 9
          RVLVLL+ V
Sbjct: 3  RVLVLLLAV 11
>NP_000574
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RVLVLLVIV 9
          RVLVLL+ V
Sbjct: 3  RVLVLLLAV 11
>NP_004435
          Length = 987

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVL+VIV
Sbjct: 550 VLVLVVIV 557
>NP_001008487
          Length = 461

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLVLLVI 8
           RVL+LLV+
Sbjct: 350 RVLLLLVV 357
>NP_001008486
          Length = 471

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLVLLVI 8
           RVL+LLV+
Sbjct: 340 RVLLLLVV 347
>NP_001008485
          Length = 507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLVLLVI 8
           RVL+LLV+
Sbjct: 376 RVLLLLVV 383
>NP_060306
          Length = 487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLVLLVI 8
           RVL+LLV+
Sbjct: 376 RVLLLLVV 383
>NP_001157947
          Length = 370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLVLLVI 8
           RVL+LLV+
Sbjct: 259 RVLLLLVV 266
>XP_005271680
          Length = 713

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLLVI+
Sbjct: 590 VLVLLVIL 597
>XP_005271679
          Length = 713

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLLVI+
Sbjct: 590 VLVLLVIL 597
>XP_005271678
          Length = 713

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLLVI+
Sbjct: 590 VLVLLVIL 597
>XP_005271676
          Length = 753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLLVI+
Sbjct: 630 VLVLLVIL 637
>XP_005271681
          Length = 772

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLLVI+
Sbjct: 649 VLVLLVIL 656
>XP_006718955
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLLVI+
Sbjct: 673 VLVLLVIL 680
>XP_006718954
          Length = 877

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLLVI+
Sbjct: 773 VLVLLVIL 780
>XP_006718953
          Length = 881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLLVI+
Sbjct: 758 VLVLLVIL 765
>XP_006718950
          Length = 896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLLVI+
Sbjct: 773 VLVLLVIL 780
>XP_005273894
          Length = 520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  RVLVLLVIV 9
          ++L+LLVI+
Sbjct: 69 KILILLVIL 77
>XP_006714240
          Length = 425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RVLVLLVIV 9
          RVLVLL+ V
Sbjct: 3  RVLVLLLAV 11
>XP_005247622
          Length = 481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLVLLVI 8
           RVL+LLV+
Sbjct: 350 RVLLLLVV 357
>XP_005247621
          Length = 502

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLVLLVI 8
           RVL+LLV+
Sbjct: 391 RVLLLLVV 398
>XP_006713744
          Length = 507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLVLLVI 8
           RVL+LLV+
Sbjct: 376 RVLLLLVV 383
>XP_005247620
          Length = 507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLVLLVI 8
           RVL+LLV+
Sbjct: 376 RVLLLLVV 383
>XP_005247619
          Length = 507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLVLLVI 8
           RVL+LLV+
Sbjct: 376 RVLLLLVV 383
>XP_005247618
          Length = 507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLVLLVI 8
           RVL+LLV+
Sbjct: 376 RVLLLLVV 383
>XP_005247617
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLVLLVI 8
           RVL+LLV+
Sbjct: 391 RVLLLLVV 398
>XP_005247616
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLVLLVI 8
           RVL+LLV+
Sbjct: 391 RVLLLLVV 398
>NP_878253
          Length = 520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  RVLVLLVIV 9
          ++L+LLVI+
Sbjct: 69 KILILLVIL 77
>NP_006718
          Length = 788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           +++LLVIV
Sbjct: 621 IIILLVIV 628
>NP_001017922
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLL++V
Sbjct: 164 VLVLLIMV 171
>NP_061008
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLL++V
Sbjct: 164 VLVLLIMV 171
>NP_001152849
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RVLVLLVIV 9
           RVLV LV+V
Sbjct: 131 RVLVDLVVV 139
>NP_001152850
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RVLVLLVIV 9
           RVLV LV+V
Sbjct: 131 RVLVDLVVV 139
>NP_073601
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RVLVLLVIV 9
           RVLV LV+V
Sbjct: 130 RVLVDLVVV 138
>NP_001152851
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RVLVLLVIV 9
           RVLV LV+V
Sbjct: 130 RVLVDLVVV 138
>NP_001152852
          Length = 363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RVLVLLVIV 9
           RVLV LV+V
Sbjct: 111 RVLVDLVVV 119
>NP_057363
          Length = 789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VL+LL++V
Sbjct: 623 VLILLILV 630
>XP_005256170
          Length = 363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RVLVLLVIV 9
           RVLV LV+V
Sbjct: 111 RVLVDLVVV 119
>XP_005256156
          Length = 363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RVLVLLVIV 9
           RVLV LV+V
Sbjct: 111 RVLVDLVVV 119
>XP_005256164
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RVLVLLVIV 9
           RVLV LV+V
Sbjct: 131 RVLVDLVVV 139
>XP_005256158
          Length = 363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RVLVLLVIV 9
           RVLV LV+V
Sbjct: 111 RVLVDLVVV 119
>XP_005256160
          Length = 363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RVLVLLVIV 9
           RVLV LV+V
Sbjct: 111 RVLVDLVVV 119
>XP_005256157
          Length = 363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RVLVLLVIV 9
           RVLV LV+V
Sbjct: 111 RVLVDLVVV 119
>XP_006710376
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLL++V
Sbjct: 164 VLVLLIMV 171
>XP_005270472
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VLVLLVIV 9
           VLVLL++V
Sbjct: 225 VLVLLIMV 232
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.358    0.175    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 260,427
Number of extensions: 512
Number of successful extensions: 52
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (17.0 bits)
S2: 28 (15.4 bits)

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