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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001121367                                                           17    4312
NP_001121368                                                           17    4312
NP_071912                                                              17    4312
NP_001138571                                                           16    5631
NP_660207                                                              16    7355
NP_060712                                                              16    7355
XP_005269600                                                           16    7355
NP_001495                                                              15    9605
NP_001136269                                                           15    9605
NP_000675                                                              15    9605
NP_001265713                                                           15    9605
NP_001258867                                                           15    9605
NP_057258                                                              15    9605
NP_057133                                                              15    9605
NP_001273689                                                           15    9605
NP_005818                                                              15    9605
NP_001020368                                                           15    9605
NP_001401                                                              15    9605
NP_061917                                                              15    9605
NP_000031                                                              15    9605
NP_001001671                                                           15    9605
XP_005262313                                                           15    9605
XP_005256986                                                           15    9605
XP_006721695                                                           15    9605
XP_005267778                                                           15    9605
XP_005252094                                                           15    9605
XP_006717200                                                           15    9605
XP_005252092                                                           15    9605
XP_006712663                                                           15    9605
XP_006712662                                                           15    9605
XP_006712661                                                           15    9605
XP_006712660                                                           15    9605
NP_003991                                                              15    9605
NP_001020370                                                           15    9605

>NP_001121367
          Length = 424

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLLVIAG 8
           RVL+V+AG
Sbjct: 207 RVLMVLAG 214



>NP_001121368
          Length = 424

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLLVIAG 8
           RVL+V+AG
Sbjct: 207 RVLMVLAG 214



>NP_071912
          Length = 424

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVLLVIAG 8
           RVL+V+AG
Sbjct: 207 RVLMVLAG 214



>NP_001138571
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVLLVIAGY 9
           +VLL ++GY
Sbjct: 339 KVLLFVSGY 347



>NP_660207
          Length = 217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVLLVIAG 8
           R+LLVI G
Sbjct: 192 RILLVILG 199



>NP_060712
          Length = 570

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  RVLLVIAG 8
          R LLV+AG
Sbjct: 36 RALLVLAG 43



>XP_005269600
          Length = 224

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVLLVIAG 8
           R+LLVI G
Sbjct: 199 RILLVILG 206



>NP_001495
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVLLVIAGY 9
           RVL ++AG+
Sbjct: 216 RVLQLVAGF 224



>NP_001136269
          Length = 415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVLLVIAGY 9
           RVL ++AG+
Sbjct: 263 RVLQLVAGF 271



>NP_000675
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VLLVIAG 8
          VLL++AG
Sbjct: 69 VLLIVAG 75



>NP_001265713
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VLLVIAG 8
          VLL++AG
Sbjct: 77 VLLIVAG 83



>NP_001258867
          Length = 2845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VLLVIAGY 9
           VLLV  GY
Sbjct: 525 VLLVAGGY 532



>NP_057258
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LVIAGY 9
           LV+AGY
Sbjct: 465 LVVAGY 470



>NP_057133
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LVIAGY 9
          LV+AGY
Sbjct: 76 LVVAGY 81



>NP_001273689
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LVIAGY 9
           LV+AGY
Sbjct: 387 LVVAGY 392



>NP_005818
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VLLVIAG 8
           VLL++AG
Sbjct: 181 VLLIVAG 187



>NP_001020368
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  RVLLVIAGY 9
          ++LL I GY
Sbjct: 86 KILLSIGGY 94



>NP_001401
          Length = 2778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VLLVIAGY 9
           VLLV  GY
Sbjct: 525 VLLVAGGY 532



>NP_061917
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  LLVIAGY 9
          LLV AGY
Sbjct: 33 LLVAAGY 39



>NP_000031
          Length = 99

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  RVLLVIA 7
          RVLLV+A
Sbjct: 4  RVLLVVA 10



>NP_001001671
          Length = 1313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VLLVIAG 8
           VLL++AG
Sbjct: 408 VLLIVAG 414



>XP_005262313
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVLLVIAGY 9
           RVL ++AG+
Sbjct: 226 RVLQLVAGF 234



>XP_005256986
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VLLVIAG 8
          VLL++AG
Sbjct: 77 VLLIVAG 83



>XP_006721695
          Length = 393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VLLVIAG 8
           VLL++AG
Sbjct: 215 VLLIVAG 221



>XP_005267778
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LVIAGY 9
          LV+AGY
Sbjct: 76 LVVAGY 81



>XP_005252094
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LVIAGY 9
           LV+AGY
Sbjct: 387 LVVAGY 392



>XP_006717200
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LVIAGY 9
           LV+AGY
Sbjct: 387 LVVAGY 392



>XP_005252092
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LVIAGY 9
           LV+AGY
Sbjct: 465 LVVAGY 470



>XP_006712663
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  LLVIAGY 9
          LLV AGY
Sbjct: 89 LLVAAGY 95



>XP_006712662
          Length = 425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  LLVIAGY 9
          LLV AGY
Sbjct: 89 LLVAAGY 95



>XP_006712661
          Length = 692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  LLVIAGY 9
          LLV AGY
Sbjct: 89 LLVAAGY 95



>XP_006712660
          Length = 693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  LLVIAGY 9
          LLV AGY
Sbjct: 89 LLVAAGY 95



>NP_003991
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RVLLVIAGY 9
           ++LL I GY
Sbjct: 96  KILLSIGGY 104



>NP_001020370
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  RVLLVIAGY 9
          ++LL I GY
Sbjct: 17 KILLSIGGY 25



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.342    0.161    0.447 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 336,777
Number of extensions: 453
Number of successful extensions: 34
Number of sequences better than 10000.0: 34
Number of HSP's gapped: 34
Number of HSP's successfully gapped: 34
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)