Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001155973                                                           19     665
NP_001020014                                                           19     665
NP_055903                                                              19     665
NP_001136025                                                           17    4312
NP_001136024                                                           17    4312
NP_060620                                                              17    4312
XP_005271054                                                           17    4312
XP_005271053                                                           17    4312
XP_005271051                                                           17    4312
XP_005271050                                                           17    4312
XP_005271049                                                           17    4312
NP_001171661                                                           16    5631
NP_004245                                                              16    5631
NP_001171665                                                           16    5631
NP_001171662                                                           16    5631
NP_444256                                                              16    7355
NP_444254                                                              16    7355
NP_444253                                                              16    7355
NP_444255                                                              16    7355
NP_001092007                                                           16    7355
NP_689499                                                              16    7355
NP_001243197                                                           16    7355
NP_001243196                                                           16    7355
NP_006693                                                              16    7355
NP_001159583                                                           16    7355
NP_001159585                                                           16    7355
NP_002042                                                              16    7355
NP_001159586                                                           16    7355
NP_115967                                                              16    7355
NP_001002295                                                           16    7355
NP_001159584                                                           16    7355
NP_055707                                                              16    7355
NP_001273128                                                           16    7355
NP_004035                                                              16    7355
NP_061928                                                              16    7355
NP_001092909                                                           16    7355
NP_443124                                                              16    7355
NP_006460                                                              16    7355
NP_115544                                                              16    7355
NP_001273123                                                           16    7355
NP_001273118                                                           16    7355
NP_001273117                                                           16    7355
XP_006718924                                                           16    7355
XP_006718107                                                           16    7355
XP_006718106                                                           16    7355
XP_005252500                                                           16    7355
XP_005252499                                                           16    7355
XP_005266139                                                           16    7355
XP_005266136                                                           16    7355
XP_006717167                                                           16    7355
XP_006717166                                                           16    7355
XP_006717165                                                           16    7355
XP_005247551                                                           16    7355
XP_005247550                                                           16    7355
XP_006713712                                                           16    7355
XP_005247549                                                           16    7355
XP_006712608                                                           16    7355
XP_005244900                                                           16    7355
NP_003202                                                              16    7355
NP_006840                                                              16    7355
NP_001070248                                                           16    7355
NP_001191335                                                           15    9605
NP_001263256                                                           15    9605
NP_001263255                                                           15    9605
NP_700357                                                              15    9605
NP_653186                                                              15    9605
NP_001157413                                                           15    9605
NP_001264044                                                           15    9605
XP_006718494                                                           15    9605
XP_005273799                                                           15    9605
XP_006718493                                                           15    9605
XP_005250558                                                           15    9605
XP_006715785                                                           15    9605
>NP_001155973
          Length = 1833

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RVAVLNGQP 9
          RVAV NGQP
Sbjct: 72 RVAVPNGQP 80
>NP_001020014
          Length = 1029

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RVAVLNGQP 9
           RVAV NGQP
Sbjct: 108 RVAVPNGQP 116
>NP_055903
          Length = 1723

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RVAVLNGQP 9
          RVAV NGQP
Sbjct: 72 RVAVPNGQP 80
>NP_001136025
          Length = 709

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RVAVLNGQP 9
           RVA LN QP
Sbjct: 528 RVADLNDQP 536
>NP_001136024
          Length = 1369

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RVAVLNGQP 9
           RVA LN QP
Sbjct: 528 RVADLNDQP 536
>NP_060620
          Length = 566

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RVAVLNGQP 9
           R AVLNG P
Sbjct: 432 RGAVLNGGP 440
>XP_005271054
          Length = 282

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RVAVLNGQP 9
           R AVLNG P
Sbjct: 148 RGAVLNGGP 156
>XP_005271053
          Length = 308

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RVAVLNGQP 9
           R AVLNG P
Sbjct: 174 RGAVLNGGP 182
>XP_005271051
          Length = 566

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RVAVLNGQP 9
           R AVLNG P
Sbjct: 432 RGAVLNGGP 440
>XP_005271050
          Length = 592

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RVAVLNGQP 9
           R AVLNG P
Sbjct: 458 RGAVLNGGP 466
>XP_005271049
          Length = 592

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RVAVLNGQP 9
           R AVLNG P
Sbjct: 458 RGAVLNGGP 466
>NP_001171661
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVAVLNGQ 8
           RVAV NG+
Sbjct: 278 RVAVFNGK 285
>NP_004245
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVAVLNGQ 8
           RVAV NG+
Sbjct: 278 RVAVFNGK 285
>NP_001171665
          Length = 419

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVAVLNGQ 8
           RVAV NG+
Sbjct: 155 RVAVFNGK 162
>NP_001171662
          Length = 451

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVAVLNGQ 8
           RVAV NG+
Sbjct: 187 RVAVFNGK 194
>NP_444256
          Length = 1794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VLNGQP 9
           +LNGQP
Sbjct: 479 LLNGQP 484
>NP_444254
          Length = 1845

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VLNGQP 9
           +LNGQP
Sbjct: 479 LLNGQP 484
>NP_444253
          Length = 1914

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VLNGQP 9
           +LNGQP
Sbjct: 548 LLNGQP 553
>NP_444255
          Length = 1863

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VLNGQP 9
           +LNGQP
Sbjct: 548 LLNGQP 553
>NP_001092007
          Length = 1342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAVLNGQP 9
           ++AVL G+P
Sbjct: 555 QLAVLTGEP 563
>NP_689499
          Length = 1317

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAVLNGQP 9
           ++AVL G+P
Sbjct: 530 QLAVLTGEP 538
>NP_001243197
          Length = 1026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VLNGQP 9
           +LNGQP
Sbjct: 813 LLNGQP 818
>NP_001243196
          Length = 1320

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    VLNGQP 9
            +LNGQP
Sbjct: 1107 LLNGQP 1112
>NP_006693
          Length = 1327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAVLNGQP 9
           ++AVL G+P
Sbjct: 535 QLAVLTGEP 543
>NP_001159583
          Length = 1375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAVLNGQP 9
           ++AVL G+P
Sbjct: 583 QLAVLTGEP 591
>NP_001159585
          Length = 1327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAVLNGQP 9
           ++AVL G+P
Sbjct: 535 QLAVLTGEP 543
>NP_002042
          Length = 443

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  AVLNGQ 8
          AVLNGQ
Sbjct: 17 AVLNGQ 22
>NP_001159586
          Length = 1365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAVLNGQP 9
           ++AVL G+P
Sbjct: 574 QLAVLTGEP 582
>NP_115967
          Length = 1320

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    VLNGQP 9
            +LNGQP
Sbjct: 1107 LLNGQP 1112
>NP_001002295
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  AVLNGQ 8
          AVLNGQ
Sbjct: 17 AVLNGQ 22
>NP_001159584
          Length = 1300

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAVLNGQP 9
           ++AVL G+P
Sbjct: 509 QLAVLTGEP 517
>NP_055707
          Length = 1271

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AVLNGQP 9
           A+L GQP
Sbjct: 797 AILGGQP 803
>NP_001273128
          Length = 1271

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AVLNGQP 9
           A+L GQP
Sbjct: 797 AILGGQP 803
>NP_004035
          Length = 592

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VAVLNGQP 9
           + VLNG P
Sbjct: 228 ITVLNGAP 235
>NP_061928
          Length = 1007

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  VLNGQP 9
          +LNGQP
Sbjct: 66 LLNGQP 71
>NP_001092909
          Length = 1008

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RVAVLNG 7
           RVA LNG
Sbjct: 424 RVAALNG 430
>NP_443124
          Length = 2459

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVAVLNGQ 8
           R+AVL GQ
Sbjct: 636 RLAVLRGQ 643
>NP_006460
          Length = 642

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VAVLNGQ 8
           VAVLNG+
Sbjct: 554 VAVLNGK 560
>NP_115544
          Length = 830

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RVAVLNGQP 9
           +  VLNG+P
Sbjct: 347 KALVLNGKP 355
>NP_001273123
          Length = 1316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AVLNGQP 9
           A+L GQP
Sbjct: 842 AILGGQP 848
>NP_001273118
          Length = 1337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AVLNGQP 9
           A+L GQP
Sbjct: 863 AILGGQP 869
>NP_001273117
          Length = 1349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AVLNGQP 9
           A+L GQP
Sbjct: 875 AILGGQP 881
>XP_006718924
          Length = 969

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  VLNGQP 9
          +LNGQP
Sbjct: 66 LLNGQP 71
>XP_006718107
          Length = 1330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    VLNGQP 9
            +LNGQP
Sbjct: 1117 LLNGQP 1122
>XP_006718106
          Length = 1338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    VLNGQP 9
            +LNGQP
Sbjct: 1125 LLNGQP 1130
>XP_005252500
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  AVLNGQ 8
          AVLNGQ
Sbjct: 17 AVLNGQ 22
>XP_005252499
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  AVLNGQ 8
          AVLNGQ
Sbjct: 17 AVLNGQ 22
>XP_005266139
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAVLNGQP 9
           ++AVL G+P
Sbjct: 556 QLAVLTGEP 564
>XP_005266136
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAVLNGQP 9
           ++AVL G+P
Sbjct: 556 QLAVLTGEP 564
>XP_006717167
          Length = 1309

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAVLNGQP 9
           ++AVL G+P
Sbjct: 522 QLAVLTGEP 530
>XP_006717166
          Length = 1316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAVLNGQP 9
           ++AVL G+P
Sbjct: 529 QLAVLTGEP 537
>XP_006717165
          Length = 1343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAVLNGQP 9
           ++AVL G+P
Sbjct: 556 QLAVLTGEP 564
>XP_005247551
          Length = 1855

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VLNGQP 9
           +LNGQP
Sbjct: 489 LLNGQP 494
>XP_005247550
          Length = 1856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VLNGQP 9
           +LNGQP
Sbjct: 558 LLNGQP 563
>XP_006713712
          Length = 1923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VLNGQP 9
           +LNGQP
Sbjct: 558 LLNGQP 563
>XP_005247549
          Length = 1924

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VLNGQP 9
           +LNGQP
Sbjct: 558 LLNGQP 563
>XP_006712608
          Length = 533

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VAVLNGQP 9
           + VLNG P
Sbjct: 169 ITVLNGAP 176
>XP_005244900
          Length = 424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VAVLNGQ 8
           VAVLNG+
Sbjct: 336 VAVLNGK 342
>NP_003202
          Length = 410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RVAVLNGQ 8
           R+AV NG+
Sbjct: 225 RIAVFNGK 232
>NP_006840
          Length = 525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AVLNGQ 8
           AVLNGQ
Sbjct: 366 AVLNGQ 371
>NP_001070248
          Length = 991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVAVLNGQ 8
           R+AVL GQ
Sbjct: 636 RLAVLRGQ 643
>NP_001191335
          Length = 218

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AVLNGQP 9
          AVL+G+P
Sbjct: 48 AVLSGEP 54
>NP_001263256
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RVAVLNGQ 8
           RVA +NG+
Sbjct: 193 RVAAINGK 200
>NP_001263255
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RVAVLNGQ 8
           RVA +NG+
Sbjct: 267 RVAAINGK 274
>NP_700357
          Length = 332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RVAVLNGQ 8
          RVA +NG+
Sbjct: 80 RVAAINGK 87
>NP_653186
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RVAVLNGQ 8
           RVA +NG+
Sbjct: 301 RVAAINGK 308
>NP_001157413
          Length = 1257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   VLNGQP 9
           +LNG+P
Sbjct: 313 ILNGEP 318
>NP_001264044
          Length = 4516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   AVLNGQ 8
           A+LNGQ
Sbjct: 498 AILNGQ 503
>XP_006718494
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RVAVLNGQ 8
           RVA +NG+
Sbjct: 291 RVAAINGK 298
>XP_005273799
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RVAVLNGQ 8
           RVA +NG+
Sbjct: 326 RVAAINGK 333
>XP_006718493
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RVAVLNGQ 8
           RVA +NG+
Sbjct: 326 RVAAINGK 333
>XP_005250558
          Length = 1024

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RVAVLNGQ 8
           RVA++NG+
Sbjct: 485 RVALVNGK 492
>XP_006715785
          Length = 279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4  VLNGQP 9
          +LNG+P
Sbjct: 16 ILNGEP 21
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.138    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 622,178
Number of extensions: 944
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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