Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1935
NP_671714                                                              18    1935
XP_006715890                                                           18    1935
XP_005250160                                                           18    1935
XP_005250159                                                           18    1935
NP_001275965                                                           16    5631
XP_005258162                                                           16    5631
XP_005258161                                                           16    5631
XP_006722385                                                           16    5631
XP_005258160                                                           16    5631
NP_055225                                                              16    5631
NP_954636                                                              16    5631
NP_115867                                                              16    7355
NP_071451                                                              15    9605
NP_056164                                                              15    9605
XP_006726587                                                           15    9605
XP_005249030                                                           15    9605
XP_005249029                                                           15    9605
XP_006710006                                                           15    9605
>NP_005742
          Length = 3907

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RVAEGSVSK 9
            R AEGSVSK
Sbjct: 1029 RGAEGSVSK 1037
>NP_671714
          Length = 3899

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RVAEGSVSK 9
            R AEGSVSK
Sbjct: 1029 RGAEGSVSK 1037
>XP_006715890
          Length = 3860

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RVAEGSVSK 9
            R AEGSVSK
Sbjct: 1029 RGAEGSVSK 1037
>XP_005250160
          Length = 3939

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RVAEGSVSK 9
            R AEGSVSK
Sbjct: 1029 RGAEGSVSK 1037
>XP_005250159
          Length = 3952

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RVAEGSVSK 9
            R AEGSVSK
Sbjct: 1029 RGAEGSVSK 1037
>NP_001275965
          Length = 518

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAEGSVSK 9
           R+ EG++SK
Sbjct: 459 RIHEGNISK 467
>XP_005258162
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAEGSVSK 9
           R+ EG++SK
Sbjct: 407 RIHEGNISK 415
>XP_005258161
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAEGSVSK 9
           R+ EG++SK
Sbjct: 407 RIHEGNISK 415
>XP_006722385
          Length = 477

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAEGSVSK 9
           R+ EG++SK
Sbjct: 418 RIHEGNISK 426
>XP_005258160
          Length = 495

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAEGSVSK 9
           R+ EG++SK
Sbjct: 436 RIHEGNISK 444
>NP_055225
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAEGSVSK 9
           R+ EG++SK
Sbjct: 407 RIHEGNISK 415
>NP_954636
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVAEGSVSK 9
           R+ EG++SK
Sbjct: 407 RIHEGNISK 415
>NP_115867
          Length = 380

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVAEGSVS 8
           RVAEG V+
Sbjct: 244 RVAEGQVT 251
>NP_071451
          Length = 1025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VAEGSVS 8
           +AEGSVS
Sbjct: 262 LAEGSVS 268
>NP_056164
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AEGSVSK 9
           AEG++SK
Sbjct: 889 AEGNISK 895
>XP_006726587
          Length = 218

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RVAEGS 6
           RVAEGS
Sbjct: 208 RVAEGS 213
>XP_005249030
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AEGSVSK 9
           AEG++SK
Sbjct: 889 AEGNISK 895
>XP_005249029
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AEGSVSK 9
           AEG++SK
Sbjct: 889 AEGNISK 895
>XP_006710006
          Length = 218

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RVAEGS 6
           RVAEGS
Sbjct: 208 RVAEGS 213
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.114    0.267 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 431,542
Number of extensions: 362
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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