Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              20     299
NP_031376                                                              17    2528
XP_006710239                                                           17    2528
NP_891550                                                              17    3301
XP_005265386                                                           17    3301
NP_001035362                                                           17    4312
NP_005711                                                              17    4312
XP_006715889                                                           17    4312
XP_006715888                                                           17    4312
NP_001273004                                                           16    5631
NP_004311                                                              16    5631
NP_775293                                                              16    5631
NP_995318                                                              16    5631
NP_001152980                                                           16    5631
NP_002216                                                              16    5631
NP_892005                                                              16    5631
NP_612501                                                              16    5631
NP_001107604                                                           16    5631
XP_006720557                                                           16    5631
XP_006720556                                                           16    5631
XP_006720555                                                           16    5631
XP_006720554                                                           16    5631
XP_005254407                                                           16    5631
XP_005254346                                                           16    5631
XP_005254347                                                           16    5631
XP_005246845                                                           16    5631
XP_006712765                                                           16    5631
XP_006712764                                                           16    5631
XP_005246844                                                           16    5631
XP_006712763                                                           16    5631
XP_006712762                                                           16    5631
XP_006712761                                                           16    5631
NP_065863                                                              16    7355
XP_005260057                                                           16    7355
XP_006722867                                                           16    7355
XP_006722866                                                           16    7355
XP_006722865                                                           16    7355
XP_005260058                                                           16    7355
NP_001004457                                                           16    7355
NP_001129628                                                           15    9605
NP_001269869                                                           15    9605
NP_001034934                                                           15    9605
NP_002171                                                              15    9605
NP_001158058                                                           15    9605
NP_001229769                                                           15    9605
NP_055725                                                              15    9605
XP_006725395                                                           15    9605
XP_006722056                                                           15    9605
XP_005274034                                                           15    9605
XP_005274033                                                           15    9605
XP_006712965                                                           15    9605
XP_005246372                                                           15    9605
XP_005273163                                                           15    9605
XP_005273162                                                           15    9605
XP_005273160                                                           15    9605
XP_005270390                                                           15    9605
XP_006711823                                                           15    9605
XP_006711680                                                           15    9605
XP_005245637                                                           15    9605
NP_733843                                                              15    9605
NP_001017434                                                           15    9605
>NP_115803
          Length = 1156

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RTRIAVCRQ 9
          R RIAVCRQ
Sbjct: 41 RARIAVCRQ 49
>NP_031376
          Length = 401

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  RTRIAVCR 8
          RTR+++CR
Sbjct: 74 RTRLSLCR 81
>XP_006710239
          Length = 485

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RTRIAVCR 8
           R+R++VCR
Sbjct: 340 RSRVSVCR 347
>NP_891550
          Length = 1935

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RTRIAVCRQ 9
            RTR+ VC++
Sbjct: 1403 RTRLVVCQR 1411
>XP_005265386
          Length = 1907

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RTRIAVCRQ 9
            RTR+ VC++
Sbjct: 1375 RTRLVVCQR 1383
>NP_001035362
          Length = 1762

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTRIAVCRQ 9
           +TR A+CR+
Sbjct: 809 QTRSAICRK 817
>NP_005711
          Length = 372

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  RTRIAVC 7
          RT+IA+C
Sbjct: 20 RTQIAIC 26
>XP_006715889
          Length = 372

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  RTRIAVC 7
          RT+IA+C
Sbjct: 20 RTQIAIC 26
>XP_006715888
          Length = 372

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  RTRIAVC 7
          RT+IA+C
Sbjct: 20 RTQIAIC 26
>NP_001273004
          Length = 869

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TRIAVCRQ 9
           T IA+CR+
Sbjct: 506 TAIAICRR 513
>NP_004311
          Length = 994

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TRIAVCRQ 9
           T IA+CR+
Sbjct: 631 TAIAICRR 638
>NP_775293
          Length = 1001

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TRIAVCRQ 9
           T IA+CR+
Sbjct: 631 TAIAICRR 638
>NP_995318
          Length = 177

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RTRIAVCR 8
          R RIA+C+
Sbjct: 53 RKRIAICQ 60
>NP_001152980
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   TRIAVCRQ 9
           TR+  CRQ
Sbjct: 304 TRLMACRQ 311
>NP_002216
          Length = 426

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   TRIAVCRQ 9
           TR+  CRQ
Sbjct: 334 TRLMACRQ 341
>NP_892005
          Length = 189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RTRIAVCR 8
          R RIA+C+
Sbjct: 53 RKRIAICQ 60
>NP_612501
          Length = 148

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RTRIAVCR 8
          R RIA+C+
Sbjct: 24 RKRIAICQ 31
>NP_001107604
          Length = 2694

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    RIAVCRQ 9
            R+A+CR+
Sbjct: 1236 RVAICRK 1242
>XP_006720557
          Length = 389

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   TRIAVCRQ 9
           TR+  CRQ
Sbjct: 334 TRLMACRQ 341
>XP_006720556
          Length = 418

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   TRIAVCRQ 9
           TR+  CRQ
Sbjct: 334 TRLMACRQ 341
>XP_006720555
          Length = 447

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   TRIAVCRQ 9
           TR+  CRQ
Sbjct: 334 TRLMACRQ 341
>XP_006720554
          Length = 468

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   TRIAVCRQ 9
           TR+  CRQ
Sbjct: 315 TRLMACRQ 322
>XP_005254407
          Length = 487

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   TRIAVCRQ 9
           TR+  CRQ
Sbjct: 334 TRLMACRQ 341
>XP_005254346
          Length = 483

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  RTRIAVCRQ 9
          +TR+ +CR+
Sbjct: 13 KTRLRLCRE 21
>XP_005254347
          Length = 483

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  RTRIAVCRQ 9
          +TR+ +CR+
Sbjct: 13 KTRLRLCRE 21
>XP_005246845
          Length = 1624

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   RIAVCRQ 9
           R+A+CR+
Sbjct: 153 RVAICRK 159
>XP_006712765
          Length = 2679

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    RIAVCRQ 9
            R+A+CR+
Sbjct: 1208 RVAICRK 1214
>XP_006712764
          Length = 2697

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    RIAVCRQ 9
            R+A+CR+
Sbjct: 1265 RVAICRK 1271
>XP_005246844
          Length = 2707

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    RIAVCRQ 9
            R+A+CR+
Sbjct: 1236 RVAICRK 1242
>XP_006712763
          Length = 2716

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    RIAVCRQ 9
            R+A+CR+
Sbjct: 1265 RVAICRK 1271
>XP_006712762
          Length = 2723

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    RIAVCRQ 9
            R+A+CR+
Sbjct: 1265 RVAICRK 1271
>XP_006712761
          Length = 2736

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    RIAVCRQ 9
            R+A+CR+
Sbjct: 1265 RVAICRK 1271
>NP_065863
          Length = 2047

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    RTRIAVCRQ 9
            +TRI VC +
Sbjct: 1886 KTRIRVCHR 1894
>XP_005260057
          Length = 2113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    RTRIAVCRQ 9
            +TRI VC +
Sbjct: 1952 KTRIRVCHR 1960
>XP_006722867
          Length = 1159

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    RTRIAVCRQ 9
            +TRI VC +
Sbjct: 998  KTRIRVCHR 1006
>XP_006722866
          Length = 1778

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    RTRIAVCRQ 9
            +TRI VC +
Sbjct: 1617 KTRIRVCHR 1625
>XP_006722865
          Length = 2078

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    RTRIAVCRQ 9
            +TRI VC +
Sbjct: 1917 KTRIRVCHR 1925
>XP_005260058
          Length = 2082

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    RTRIAVCRQ 9
            +TRI VC +
Sbjct: 1921 KTRIRVCHR 1929
>NP_001004457
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   TRIAVCRQ 9
           TR+A C Q
Sbjct: 181 TRVAFCAQ 188
>NP_001129628
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RTRIAVCRQ 9
           +TRI  C+Q
Sbjct: 693 KTRIYQCKQ 701
>NP_001269869
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   RTRIAVCR 8
           R+R+ +CR
Sbjct: 230 RSRVPLCR 237
>NP_001034934
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   RTRIAVCR 8
           R+R+ +CR
Sbjct: 230 RSRVPLCR 237
>NP_002171
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   RIAVCRQ 9
           R+A+C+Q
Sbjct: 254 RLALCKQ 260
>NP_001158058
          Length = 3708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    RTRIAVCRQ 9
            R R+A C Q
Sbjct: 3491 RIRVAACPQ 3499
>NP_001229769
          Length = 241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RTRIAVC 7
           R R+AVC
Sbjct: 189 RLRLAVC 195
>NP_055725
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RTRIAVCRQ 9
           +TRI  C+Q
Sbjct: 693 KTRIYQCKQ 701
>XP_006725395
          Length = 1249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    RTRIAVCR 8
            RTR  +CR
Sbjct: 1209 RTRAPLCR 1216
>XP_006722056
          Length = 1249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    RTRIAVCR 8
            RTR  +CR
Sbjct: 1209 RTRAPLCR 1216
>XP_005274034
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   RIAVCRQ 9
           R+A+C+Q
Sbjct: 254 RLALCKQ 260
>XP_005274033
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   RIAVCRQ 9
           R+A+C+Q
Sbjct: 254 RLALCKQ 260
>XP_006712965
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1  RTRIAVCR 8
          RTR   CR
Sbjct: 47 RTRTTACR 54
>XP_005246372
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   RTRIAVCR 8
           R+R+ +CR
Sbjct: 132 RSRVPLCR 139
>XP_005273163
          Length = 220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RTRIAVC 7
           R R+AVC
Sbjct: 168 RLRLAVC 174
>XP_005273162
          Length = 220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RTRIAVC 7
           R R+AVC
Sbjct: 168 RLRLAVC 174
>XP_005273160
          Length = 286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RTRIAVC 7
           R R+AVC
Sbjct: 234 RLRLAVC 240
>XP_005270390
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RTRIAVC 7
           RTR A+C
Sbjct: 557 RTRCALC 563
>XP_006711823
          Length = 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RTRIAVC 7
           RTR A+C
Sbjct: 560 RTRCALC 566
>XP_006711680
          Length = 3617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    RTRIAVCRQ 9
            R R+A C Q
Sbjct: 3400 RIRVAACPQ 3408
>XP_005245637
          Length = 3683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    RTRIAVCRQ 9
            R R+A C Q
Sbjct: 3466 RIRVAACPQ 3474
>NP_733843
          Length = 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RTRIAVC 7
           RTR A+C
Sbjct: 560 RTRCALC 566
>NP_001017434
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RTRIAVC 7
           RTR A+C
Sbjct: 309 RTRCALC 315
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.346    0.138    0.444 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 580,240
Number of extensions: 609
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

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