Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     869
NP_671714                                                              19     869
XP_006715890                                                           19     869
XP_005250160                                                           19     869
XP_005250159                                                           19     869
NP_002435                                                              17    3301
XP_005262326                                                           17    3301
NP_037379                                                              16    5631
NP_659540                                                              16    5631
NP_653321                                                              16    5631
NP_001092903                                                           16    5631
NP_065885                                                              16    5631
NP_001098991                                                           16    5631
XP_006717843                                                           16    5631
XP_005252734                                                           16    5631
XP_005252733                                                           16    5631
XP_005252732                                                           16    5631
XP_005252731                                                           16    5631
XP_005252730                                                           16    5631
XP_005252729                                                           16    5631
XP_005264323                                                           16    5631
NP_001139784                                                           16    7355
NP_705832                                                              16    7355
NP_054767                                                              16    7355
XP_005256920                                                           16    7355
XP_006720977                                                           16    7355
XP_006720976                                                           16    7355
XP_006720975                                                           16    7355
XP_005255512                                                           16    7355
XP_006720974                                                           16    7355
XP_005255510                                                           16    7355
XP_006720973                                                           16    7355
XP_006720972                                                           16    7355
XP_006720971                                                           16    7355
XP_005255508                                                           16    7355
XP_005255509                                                           16    7355
NP_776248                                                              15    9605
NP_009117                                                              15    9605
NP_055986                                                              15    9605
NP_065905                                                              15    9605
NP_001257869                                                           15    9605
XP_005260322                                                           15    9605
XP_005260321                                                           15    9605
XP_005260320                                                           15    9605
XP_006723758                                                           15    9605
XP_006723757                                                           15    9605
XP_006723756                                                           15    9605
XP_006723755                                                           15    9605
XP_006723754                                                           15    9605
XP_006723753                                                           15    9605
XP_005260319                                                           15    9605
XP_006722578                                                           15    9605
XP_005266789                                                           15    9605
XP_006722577                                                           15    9605
XP_006722576                                                           15    9605
XP_005266788                                                           15    9605
XP_005266787                                                           15    9605
XP_005255257                                                           15    9605
XP_005255256                                                           15    9605
XP_005255255                                                           15    9605
XP_005255254                                                           15    9605
XP_005255252                                                           15    9605
>NP_005742
          Length = 3907

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RTREQLAVE 9
            R REQLAVE
Sbjct: 1908 RAREQLAVE 1916
>NP_671714
          Length = 3899

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RTREQLAVE 9
            R REQLAVE
Sbjct: 1908 RAREQLAVE 1916
>XP_006715890
          Length = 3860

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RTREQLAVE 9
            R REQLAVE
Sbjct: 1861 RAREQLAVE 1869
>XP_005250160
          Length = 3939

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RTREQLAVE 9
            R REQLAVE
Sbjct: 1940 RAREQLAVE 1948
>XP_005250159
          Length = 3952

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RTREQLAVE 9
            R REQLAVE
Sbjct: 1940 RAREQLAVE 1948
>NP_002435
          Length = 577

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   RTREQLAVE 9
           +T+EQLA+E
Sbjct: 412 KTQEQLALE 420
>XP_005262326
          Length = 578

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   RTREQLAVE 9
           +T+EQLA+E
Sbjct: 413 KTQEQLALE 421
>NP_037379
          Length = 458

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RTREQLAVE 9
           RT+ QLAV+
Sbjct: 432 RTQSQLAVQ 440
>NP_659540
          Length = 361

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RTREQLAVE 9
           RT+ QLAV+
Sbjct: 335 RTQSQLAVQ 343
>NP_653321
          Length = 626

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RTREQLAVE 9
           RTREQL  +
Sbjct: 520 RTREQLQAD 528
>NP_001092903
          Length = 831

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RTREQLAVE 9
           RTREQL  +
Sbjct: 520 RTREQLQAD 528
>NP_065885
          Length = 550

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RTREQLAV 8
           +T+EQLA+
Sbjct: 363 KTKEQLAI 370
>NP_001098991
          Length = 844

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RTREQLAVE 9
           +TREQL  E
Sbjct: 534 KTREQLQAE 542
>XP_006717843
          Length = 844

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RTREQLAVE 9
           +TREQL  E
Sbjct: 534 KTREQLQAE 542
>XP_005252734
          Length = 846

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RTREQLAVE 9
           +TREQL  E
Sbjct: 534 KTREQLQAE 542
>XP_005252733
          Length = 916

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RTREQLAVE 9
           +TREQL  E
Sbjct: 460 KTREQLQAE 468
>XP_005252732
          Length = 976

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RTREQLAVE 9
           +TREQL  E
Sbjct: 534 KTREQLQAE 542
>XP_005252731
          Length = 988

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RTREQLAVE 9
           +TREQL  E
Sbjct: 534 KTREQLQAE 542
>XP_005252730
          Length = 990

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RTREQLAVE 9
           +TREQL  E
Sbjct: 534 KTREQLQAE 542
>XP_005252729
          Length = 990

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RTREQLAVE 9
           +TREQL  E
Sbjct: 534 KTREQLQAE 542
>XP_005264323
          Length = 426

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RTREQLAVE 9
           RT+ QLAV+
Sbjct: 400 RTQSQLAVQ 408
>NP_001139784
          Length = 986

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  RTREQLA 7
          RT+EQLA
Sbjct: 28 RTQEQLA 34
>NP_705832
          Length = 938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  RTREQLA 7
          RT+EQLA
Sbjct: 28 RTQEQLA 34
>NP_054767
          Length = 1049

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RTREQL 6
          RTREQL
Sbjct: 61 RTREQL 66
>XP_005256920
          Length = 943

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  RTREQLA 7
          RT+EQLA
Sbjct: 28 RTQEQLA 34
>XP_006720977
          Length = 1049

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RTREQL 6
          RTREQL
Sbjct: 61 RTREQL 66
>XP_006720976
          Length = 1053

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RTREQL 6
          RTREQL
Sbjct: 61 RTREQL 66
>XP_006720975
          Length = 1070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RTREQL 6
          RTREQL
Sbjct: 32 RTREQL 37
>XP_005255512
          Length = 1088

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RTREQL 6
          RTREQL
Sbjct: 50 RTREQL 55
>XP_006720974
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RTREQL 6
          RTREQL
Sbjct: 61 RTREQL 66
>XP_005255510
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RTREQL 6
          RTREQL
Sbjct: 61 RTREQL 66
>XP_006720973
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RTREQL 6
          RTREQL
Sbjct: 61 RTREQL 66
>XP_006720972
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RTREQL 6
          RTREQL
Sbjct: 61 RTREQL 66
>XP_006720971
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RTREQL 6
          RTREQL
Sbjct: 61 RTREQL 66
>XP_005255508
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RTREQL 6
          RTREQL
Sbjct: 61 RTREQL 66
>XP_005255509
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RTREQL 6
          RTREQL
Sbjct: 61 RTREQL 66
>NP_776248
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TREQLA 7
           TREQLA
Sbjct: 189 TREQLA 194
>NP_009117
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RTREQLAVE 9
            R  E+LAVE
Sbjct: 1870 RLEEELAVE 1878
>NP_055986
          Length = 1125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TREQLA 7
           TREQLA
Sbjct: 870 TREQLA 875
>NP_065905
          Length = 1216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TREQLAV 8
           +REQLAV
Sbjct: 803 SREQLAV 809
>NP_001257869
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TREQLA 7
           TREQLA
Sbjct: 856 TREQLA 861
>XP_005260322
          Length = 1810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RTREQLAVE 9
            R  E+LAVE
Sbjct: 1238 RLEEELAVE 1246
>XP_005260321
          Length = 2365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RTREQLAVE 9
            R  E+LAVE
Sbjct: 1793 RLEEELAVE 1801
>XP_005260320
          Length = 2370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RTREQLAVE 9
            R  E+LAVE
Sbjct: 1870 RLEEELAVE 1878
>XP_006723758
          Length = 2386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RTREQLAVE 9
            R  E+LAVE
Sbjct: 1814 RLEEELAVE 1822
>XP_006723757
          Length = 2404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RTREQLAVE 9
            R  E+LAVE
Sbjct: 1870 RLEEELAVE 1878
>XP_006723756
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RTREQLAVE 9
            R  E+LAVE
Sbjct: 1870 RLEEELAVE 1878
>XP_006723755
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RTREQLAVE 9
            R  E+LAVE
Sbjct: 1870 RLEEELAVE 1878
>XP_006723754
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RTREQLAVE 9
            R  E+LAVE
Sbjct: 1870 RLEEELAVE 1878
>XP_006723753
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RTREQLAVE 9
            R  E+LAVE
Sbjct: 1870 RLEEELAVE 1878
>XP_005260319
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RTREQLAVE 9
            R  E+LAVE
Sbjct: 1870 RLEEELAVE 1878
>XP_006722578
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TREQLAV 8
           +REQLAV
Sbjct: 447 SREQLAV 453
>XP_005266789
          Length = 999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TREQLAV 8
           +REQLAV
Sbjct: 803 SREQLAV 809
>XP_006722577
          Length = 1043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TREQLAV 8
           +REQLAV
Sbjct: 803 SREQLAV 809
>XP_006722576
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TREQLAV 8
           +REQLAV
Sbjct: 803 SREQLAV 809
>XP_005266788
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TREQLAV 8
           +REQLAV
Sbjct: 779 SREQLAV 785
>XP_005266787
          Length = 1216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TREQLAV 8
           +REQLAV
Sbjct: 803 SREQLAV 809
>XP_005255257
          Length = 774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TREQLA 7
           TREQLA
Sbjct: 519 TREQLA 524
>XP_005255256
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TREQLA 7
           TREQLA
Sbjct: 525 TREQLA 530
>XP_005255255
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TREQLA 7
           TREQLA
Sbjct: 696 TREQLA 701
>XP_005255254
          Length = 1051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TREQLA 7
           TREQLA
Sbjct: 796 TREQLA 801
>XP_005255252
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TREQLA 7
           TREQLA
Sbjct: 869 TREQLA 874
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.123    0.290 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 398,228
Number of extensions: 507
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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