Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001005415                                                           17    3301
XP_006722825                                                           17    3301
NP_057580                                                              17    3301
NP_055809                                                              16    7355
NP_001128493                                                           16    7355
NP_001122080                                                           16    7355
NP_001128495                                                           16    7355
NP_001128494                                                           16    7355
NP_115589                                                              16    7355
NP_001252540                                                           16    7355
NP_542166                                                              16    7355
NP_056357                                                              16    7355
NP_001269937                                                           16    7355
NP_001269936                                                           16    7355
NP_001269934                                                           16    7355
NP_001269933                                                           16    7355
NP_001269932                                                           16    7355
NP_001269931                                                           16    7355
NP_001269930                                                           16    7355
NP_001269929                                                           16    7355
NP_001269927                                                           16    7355
NP_001269925                                                           16    7355
NP_001269924                                                           16    7355
NP_003425                                                              16    7355
NP_001257337                                                           16    7355
NP_001076799                                                           16    7355
NP_001269928                                                           16    7355
NP_001269935                                                           16    7355
NP_001269926                                                           16    7355
NP_067042                                                              16    7355
XP_006724100                                                           16    7355
XP_006723682                                                           16    7355
XP_006723681                                                           16    7355
XP_006723680                                                           16    7355
XP_006723679                                                           16    7355
XP_005260880                                                           16    7355
XP_005260877                                                           16    7355
XP_005260876                                                           16    7355
XP_005260875                                                           16    7355
XP_006720502                                                           16    7355
XP_006720501                                                           16    7355
XP_005264655                                                           16    7355
XP_005264654                                                           16    7355
XP_005264653                                                           16    7355
NP_001245135                                                           15    9605
NP_001245136                                                           15    9605
NP_005419                                                              15    9605
NP_003451                                                              15    9605
NP_001230085                                                           15    9605
NP_006292                                                              15    9605
NP_005670                                                              15    9605
NP_647610                                                              15    9605
NP_001180440                                                           15    9605
NP_001277033                                                           15    9605
XP_006721392                                                           15    9605
XP_006721391                                                           15    9605
XP_005256284                                                           15    9605
XP_006721390                                                           15    9605
XP_006721389                                                           15    9605
XP_005256283                                                           15    9605
XP_006721388                                                           15    9605
XP_005255619                                                           15    9605
XP_006719652                                                           15    9605
XP_006719651                                                           15    9605
XP_005269195                                                           15    9605
NP_001929                                                              15    9605
>NP_001005415
          Length = 246

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RTEKRTI 7
           RTEKRT+
Sbjct: 132 RTEKRTL 138
>XP_006722825
          Length = 246

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RTEKRTI 7
           RTEKRT+
Sbjct: 132 RTEKRTL 138
>NP_057580
          Length = 246

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RTEKRTI 7
           RTEKRT+
Sbjct: 132 RTEKRTL 138
>NP_055809
          Length = 1508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RTEKRTISS 9
            R+E R+ISS
Sbjct: 1085 RSESRSISS 1093
>NP_001128493
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RTEKRTIS 8
           RT+++TIS
Sbjct: 300 RTQRKTIS 307
>NP_001122080
          Length = 1514

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RTEKRTISS 9
            R+E R+ISS
Sbjct: 1091 RSESRSISS 1099
>NP_001128495
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RTEKRTIS 8
           RT+++TIS
Sbjct: 300 RTQRKTIS 307
>NP_001128494
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RTEKRTIS 8
           RT+++TIS
Sbjct: 300 RTQRKTIS 307
>NP_115589
          Length = 391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RTEKRTIS 8
           RT+++TIS
Sbjct: 300 RTQRKTIS 307
>NP_001252540
          Length = 1231

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RTEKRTISS 9
            R+E R+ISS
Sbjct: 1085 RSESRSISS 1093
>NP_542166
          Length = 1272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  TEKRTISS 9
          +E+RT+SS
Sbjct: 26 SERRTVSS 33
>NP_056357
          Length = 1272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  TEKRTISS 9
          +E+RT+SS
Sbjct: 26 SERRTVSS 33
>NP_001269937
          Length = 559

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RTEKRTISS 9
          RT+KRT+ +
Sbjct: 62 RTKKRTLGA 70
>NP_001269936
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 170 RTKKRTLGA 178
>NP_001269934
          Length = 635

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 138 RTKKRTLGA 146
>NP_001269933
          Length = 591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 94  RTKKRTLGA 102
>NP_001269932
          Length = 591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 94  RTKKRTLGA 102
>NP_001269931
          Length = 657

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 160 RTKKRTLGA 168
>NP_001269930
          Length = 654

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 157 RTKKRTLGA 165
>NP_001269929
          Length = 654

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 157 RTKKRTLGA 165
>NP_001269927
          Length = 654

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 157 RTKKRTLGA 165
>NP_001269925
          Length = 671

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 174 RTKKRTLGA 182
>NP_001269924
          Length = 653

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 156 RTKKRTLGA 164
>NP_003425
          Length = 653

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 156 RTKKRTLGA 164
>NP_001257337
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RTEKRTISS 9
          +T K+T+SS
Sbjct: 51 KTPKKTVSS 59
>NP_001076799
          Length = 653

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 156 RTKKRTLGA 164
>NP_001269928
          Length = 654

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 157 RTKKRTLGA 165
>NP_001269935
          Length = 661

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 164 RTKKRTLGA 172
>NP_001269926
          Length = 654

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 157 RTKKRTLGA 165
>NP_067042
          Length = 298

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RTEKRTISS 9
          +T K+T+SS
Sbjct: 51 KTPKKTVSS 59
>XP_006724100
          Length = 305

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RTEKRTISS 9
          +T K+T+SS
Sbjct: 51 KTPKKTVSS 59
>XP_006723682
          Length = 559

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RTEKRTISS 9
          RT+KRT+ +
Sbjct: 62 RTKKRTLGA 70
>XP_006723681
          Length = 590

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 93  RTKKRTLGA 101
>XP_006723680
          Length = 591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 94  RTKKRTLGA 102
>XP_006723679
          Length = 654

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 157 RTKKRTLGA 165
>XP_005260880
          Length = 654

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 157 RTKKRTLGA 165
>XP_005260877
          Length = 654

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 157 RTKKRTLGA 165
>XP_005260876
          Length = 654

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 157 RTKKRTLGA 165
>XP_005260875
          Length = 656

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+KRT+ +
Sbjct: 159 RTKKRTLGA 167
>XP_006720502
          Length = 931

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           R+E R+ISS
Sbjct: 508 RSESRSISS 516
>XP_006720501
          Length = 1459

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RTEKRTISS 9
            R+E R+ISS
Sbjct: 1036 RSESRSISS 1044
>XP_005264655
          Length = 391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RTEKRTIS 8
           RT+++TIS
Sbjct: 300 RTQRKTIS 307
>XP_005264654
          Length = 391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RTEKRTIS 8
           RT+++TIS
Sbjct: 300 RTQRKTIS 307
>XP_005264653
          Length = 391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RTEKRTIS 8
           RT+++TIS
Sbjct: 300 RTQRKTIS 307
>NP_001245135
          Length = 823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EKRTIS 8
           EKRTIS
Sbjct: 747 EKRTIS 752
>NP_001245136
          Length = 813

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EKRTIS 8
           EKRTIS
Sbjct: 737 EKRTIS 742
>NP_005419
          Length = 845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EKRTIS 8
           EKRTIS
Sbjct: 769 EKRTIS 774
>NP_003451
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EKRTISS 9
           EKRT+S+
Sbjct: 738 EKRTVSN 744
>NP_001230085
          Length = 843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+K+T+ S
Sbjct: 138 RTKKKTVVS 146
>NP_006292
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           R++KR ISS
Sbjct: 711 RSQKRGISS 719
>NP_005670
          Length = 869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+K+T+ S
Sbjct: 138 RTKKKTVVS 146
>NP_647610
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RTEKRTISS 9
          RT+K+T+ S
Sbjct: 71 RTKKKTVVS 79
>NP_001180440
          Length = 892

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           R++KR ISS
Sbjct: 744 RSQKRGISS 752
>NP_001277033
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EKRTISS 9
           EKRT+S+
Sbjct: 729 EKRTVSN 735
>XP_006721392
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RTEKRTISS 9
          RT+K+T+ S
Sbjct: 13 RTKKKTVVS 21
>XP_006721391
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RTEKRTISS 9
          RT+K+T+ S
Sbjct: 13 RTKKKTVVS 21
>XP_005256284
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RTEKRTISS 9
          RT+K+T+ S
Sbjct: 71 RTKKKTVVS 79
>XP_006721390
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+K+T+ S
Sbjct: 139 RTKKKTVVS 147
>XP_006721389
          Length = 844

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+K+T+ S
Sbjct: 139 RTKKKTVVS 147
>XP_005256283
          Length = 869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+K+T+ S
Sbjct: 138 RTKKKTVVS 146
>XP_006721388
          Length = 870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           RT+K+T+ S
Sbjct: 139 RTKKKTVVS 147
>XP_005255619
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EKRTISS 9
           EKRT+S+
Sbjct: 827 EKRTVSN 833
>XP_006719652
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           R++KR ISS
Sbjct: 611 RSQKRGISS 619
>XP_006719651
          Length = 892

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           R++KR ISS
Sbjct: 744 RSQKRGISS 752
>XP_005269195
          Length = 892

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RTEKRTISS 9
           R++KR ISS
Sbjct: 744 RSQKRGISS 752
>NP_001929
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  RTEKRTIS 8
          ++EK+TIS
Sbjct: 60 KSEKKTIS 67
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.109    0.248 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 436,069
Number of extensions: 555
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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