Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001257436                                                           18    1482
NP_001257437                                                           18    1482
NP_006281                                                              18    1482
XP_006715618                                                           18    1482
XP_005267176                                                           18    1482
NP_001160158                                                           17    3301
XP_005269036                                                           17    3301
XP_005269035                                                           17    3301
XP_005269034                                                           17    3301
XP_005269033                                                           17    3301
XP_005269032                                                           17    3301
XP_005269031                                                           17    3301
NP_001035194                                                           17    4312
NP_001185867                                                           16    5631
NP_001185869                                                           16    5631
NP_001185870                                                           16    5631
NP_001382                                                              16    5631
NP_001185871                                                           16    5631
NP_001185868                                                           16    5631
NP_116763                                                              16    5631
NP_001185872                                                           16    5631
NP_116757                                                              16    5631
NP_116761                                                              16    5631
NP_001185873                                                           16    5631
NP_116762                                                              16    5631
NP_001381                                                              16    5631
NP_116760                                                              16    5631
XP_006722477                                                           16    5631
XP_006722476                                                           16    5631
XP_006722475                                                           16    5631
XP_005258281                                                           16    5631
XP_006722474                                                           16    5631
XP_006722473                                                           16    5631
XP_005258280                                                           16    5631
XP_006722472                                                           16    5631
XP_006722471                                                           16    5631
XP_005258279                                                           16    5631
XP_005258278                                                           16    5631
XP_005258277                                                           16    5631
XP_006722470                                                           16    5631
XP_006722469                                                           16    5631
XP_005258276                                                           16    5631
XP_005258275                                                           16    5631
XP_005258274                                                           16    5631
XP_006722468                                                           16    5631
XP_005258273                                                           16    5631
XP_006722467                                                           16    5631
XP_006722466                                                           16    5631
XP_006722465                                                           16    5631
XP_005258269                                                           16    5631
XP_006722464                                                           16    5631
XP_006722463                                                           16    5631
XP_006722462                                                           16    5631
XP_005258264                                                           16    5631
XP_006722461                                                           16    5631
XP_006722460                                                           16    5631
XP_006722459                                                           16    5631
XP_006722458                                                           16    5631
NP_055527                                                              15    9605
NP_775768                                                              15    9605
NP_612361                                                              15    9605
NP_001271203                                                           15    9605
NP_877497                                                              15    9605
XP_006721170                                                           15    9605
XP_006721169                                                           15    9605
XP_005255780                                                           15    9605
>NP_001257436
          Length = 790

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           RT AEASSS
Sbjct: 542 RTTAEASSS 550
>NP_001257437
          Length = 790

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           RT AEASSS
Sbjct: 542 RTTAEASSS 550
>NP_006281
          Length = 790

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           RT AEASSS
Sbjct: 542 RTTAEASSS 550
>XP_006715618
          Length = 577

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           RT AEASSS
Sbjct: 329 RTTAEASSS 337
>XP_005267176
          Length = 790

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           RT AEASSS
Sbjct: 542 RTTAEASSS 550
>NP_001160158
          Length = 851

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RTAAEASSS 9
          RTA EAS+S
Sbjct: 26 RTAGEASTS 34
>XP_005269036
          Length = 851

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RTAAEASSS 9
          RTA EAS+S
Sbjct: 26 RTAGEASTS 34
>XP_005269035
          Length = 851

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RTAAEASSS 9
          RTA EAS+S
Sbjct: 26 RTAGEASTS 34
>XP_005269034
          Length = 851

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RTAAEASSS 9
          RTA EAS+S
Sbjct: 26 RTAGEASTS 34
>XP_005269033
          Length = 883

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RTAAEASSS 9
          RTA EAS+S
Sbjct: 26 RTAGEASTS 34
>XP_005269032
          Length = 883

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RTAAEASSS 9
          RTA EAS+S
Sbjct: 26 RTAGEASTS 34
>XP_005269031
          Length = 883

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RTAAEASSS 9
          RTA EAS+S
Sbjct: 26 RTAGEASTS 34
>NP_001035194
          Length = 4493

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    TAAEASSS 9
            T+AEASSS
Sbjct: 2725 TSAEASSS 2732

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    TAAEASSS 9
            T+AEASSS
Sbjct: 2961 TSAEASSS 2968
>NP_001185867
          Length = 724

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 383 RLAAESSSS 391
>NP_001185869
          Length = 683

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 383 RLAAESSSS 391
>NP_001185870
          Length = 510

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 383 RLAAESSSS 391
>NP_001382
          Length = 570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 443 RLAAESSSS 451
>NP_001185871
          Length = 452

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 152 RLAAESSSS 160
>NP_001185868
          Length = 690

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 383 RLAAESSSS 391
>NP_116763
          Length = 192

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RTAAEASSS 9
          R AAE+SSS
Sbjct: 65 RLAAESSSS 73
>NP_001185872
          Length = 433

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 133 RLAAESSSS 141
>NP_116757
          Length = 686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 386 RLAAESSSS 394
>NP_116761
          Length = 513

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 386 RLAAESSSS 394
>NP_001185873
          Length = 395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 95  RLAAESSSS 103
>NP_116762
          Length = 391

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RTAAEASSS 9
          R AAE+SSS
Sbjct: 91 RLAAESSSS 99
>NP_001381
          Length = 743

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 443 RLAAESSSS 451
>NP_116760
          Length = 567

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 440 RLAAESSSS 448
>XP_006722477
          Length = 412

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RTAAEASSS 9
          R AAE+SSS
Sbjct: 65 RLAAESSSS 73
>XP_006722476
          Length = 413

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RTAAEASSS 9
          R AAE+SSS
Sbjct: 65 RLAAESSSS 73
>XP_006722475
          Length = 443

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 95  RLAAESSSS 103
>XP_005258281
          Length = 500

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 152 RLAAESSSS 160
>XP_006722474
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 155 RLAAESSSS 163
>XP_006722473
          Length = 513

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 386 RLAAESSSS 394
>XP_005258280
          Length = 567

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 440 RLAAESSSS 448
>XP_006722472
          Length = 570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 443 RLAAESSSS 451
>XP_006722471
          Length = 686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 386 RLAAESSSS 394
>XP_005258279
          Length = 709

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 409 RLAAESSSS 417
>XP_005258278
          Length = 713

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 413 RLAAESSSS 421
>XP_005258277
          Length = 731

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 383 RLAAESSSS 391
>XP_006722470
          Length = 734

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 386 RLAAESSSS 394
>XP_006722469
          Length = 743

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 443 RLAAESSSS 451
>XP_005258276
          Length = 747

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 440 RLAAESSSS 448
>XP_005258275
          Length = 760

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 413 RLAAESSSS 421
>XP_005258274
          Length = 761

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 413 RLAAESSSS 421
>XP_006722468
          Length = 764

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 416 RLAAESSSS 424
>XP_005258273
          Length = 770

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 470 RLAAESSSS 478
>XP_006722467
          Length = 773

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 473 RLAAESSSS 481
>XP_006722466
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 473 RLAAESSSS 481
>XP_006722465
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 473 RLAAESSSS 481
>XP_005258269
          Length = 788

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 440 RLAAESSSS 448
>XP_006722464
          Length = 790

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 442 RLAAESSSS 450
>XP_006722463
          Length = 791

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 443 RLAAESSSS 451
>XP_006722462
          Length = 814

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 473 RLAAESSSS 481
>XP_005258264
          Length = 818

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 470 RLAAESSSS 478
>XP_006722461
          Length = 821

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 473 RLAAESSSS 481
>XP_006722460
          Length = 821

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 473 RLAAESSSS 481
>XP_006722459
          Length = 821

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 473 RLAAESSSS 481
>XP_006722458
          Length = 821

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           R AAE+SSS
Sbjct: 473 RLAAESSSS 481
>NP_055527
          Length = 1707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TAAEASSS 9
           TAA ASSS
Sbjct: 331 TAATASSS 338
>NP_775768
          Length = 207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           RT+ +ASSS
Sbjct: 105 RTSMDASSS 113
>NP_612361
          Length = 538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TAAEASSS 9
          TAA ASSS
Sbjct: 18 TAAAASSS 25
>NP_001271203
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           RT+ +ASSS
Sbjct: 105 RTSMDASSS 113
>NP_877497
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RTAAEASSS 9
           RT+ +ASSS
Sbjct: 105 RTSMDASSS 113
>XP_006721170
          Length = 1707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TAAEASSS 9
           TAA ASSS
Sbjct: 331 TAATASSS 338
>XP_006721169
          Length = 1707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TAAEASSS 9
           TAA ASSS
Sbjct: 331 TAATASSS 338
>XP_005255780
          Length = 1707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TAAEASSS 9
           TAA ASSS
Sbjct: 331 TAATASSS 338
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.273   0.0805    0.162 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 206,058
Number of extensions: 205
Number of successful extensions: 67
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.7 bits)
S2: 28 (15.4 bits)

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