Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001161842                                                           16    5631
NP_055595                                                              16    5631
NP_001035879                                                           16    5631
NP_653316                                                              16    5631
XP_006719908                                                           16    5631
XP_006719907                                                           16    5631
XP_006715348                                                           16    5631
XP_005249560                                                           16    5631
XP_005264948                                                           16    5631
XP_005264946                                                           16    5631
NP_001171079                                                           16    7355
NP_001934                                                              16    7355
NP_065988                                                              16    7355
NP_065750                                                              16    7355
NP_001763                                                              16    7355
NP_004317                                                              16    7355
NP_001241872                                                           16    7355
NP_001129069                                                           16    7355
NP_060554                                                              16    7355
NP_077024                                                              16    7355
XP_005259491                                                           16    7355
XP_005259490                                                           16    7355
XP_005267986                                                           16    7355
XP_006715118                                                           16    7355
XP_005264480                                                           16    7355
XP_005264478                                                           16    7355
XP_005264475                                                           16    7355
XP_005277475                                                           16    7355
XP_005277474                                                           16    7355
XP_006711546                                                           16    7355
XP_005273028                                                           16    7355
XP_005245421                                                           16    7355
XP_006711532                                                           16    7355
XP_005245420                                                           16    7355
NP_277047                                                              15    9605
NP_000292                                                              15    9605
NP_003309                                                              15    9605
NP_001160163                                                           15    9605
NP_078966                                                              15    9605
NP_001229725                                                           15    9605
NP_001229724                                                           15    9605
NP_055209                                                              15    9605
NP_055484                                                              15    9605
XP_006723004                                                           15    9605
XP_005256320                                                           15    9605
NP_001139669                                                           15    9605
NP_001001919                                                           15    9605
>NP_001161842
          Length = 1782

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    SPVVQN 7
            SPVVQN
Sbjct: 1132 SPVVQN 1137
>NP_055595
          Length = 1698

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    SPVVQN 7
            SPVVQN
Sbjct: 1048 SPVVQN 1053
>NP_001035879
          Length = 523

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SPVVQNKL 9
           SPVV N+L
Sbjct: 164 SPVVSNEL 171
>NP_653316
          Length = 833

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SPVVQNK 8
          SPVV NK
Sbjct: 46 SPVVSNK 52
>XP_006719908
          Length = 427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SPVVQNKL 9
           SPVV N+L
Sbjct: 164 SPVVSNEL 171
>XP_006719907
          Length = 523

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SPVVQNKL 9
           SPVV N+L
Sbjct: 164 SPVVSNEL 171
>XP_006715348
          Length = 1734

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    SPVVQN 7
            SPVVQN
Sbjct: 1080 SPVVQN 1085
>XP_005249560
          Length = 1750

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    SPVVQN 7
            SPVVQN
Sbjct: 1100 SPVVQN 1105
>XP_005264948
          Length = 581

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SPVVQNK 8
          SPVV NK
Sbjct: 46 SPVVSNK 52
>XP_005264946
          Length = 810

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SPVVQNK 8
          SPVV NK
Sbjct: 46 SPVVSNK 52
>NP_001171079
          Length = 310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  SPVVQNKL 9
          SPV  NKL
Sbjct: 71 SPVATNKL 78
>NP_001934
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PVVQNKL 9
           PVV+NK+
Sbjct: 270 PVVENKV 276
>NP_065988
          Length = 2048

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    RSPVVQNK 8
            RSP++ NK
Sbjct: 1570 RSPMMNNK 1577
>NP_065750
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RSPVVQN 7
           ++PVVQN
Sbjct: 199 KTPVVQN 205
>NP_001763
          Length = 364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  SPVVQNKL 9
          SPV  NKL
Sbjct: 71 SPVATNKL 78
>NP_004317
          Length = 1426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SPVVQNKL 9
           SP V+NKL
Sbjct: 278 SPGVENKL 285
>NP_001241872
          Length = 1796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SPVVQNKL 9
            SPV+Q+K+
Sbjct: 1652 SPVLQHKI 1659
>NP_001129069
          Length = 1870

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SPVVQNKL 9
            SPV+Q+K+
Sbjct: 1652 SPVLQHKI 1659
>NP_060554
          Length = 1843

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SPVVQNKL 9
            SPV+Q+K+
Sbjct: 1625 SPVLQHKI 1632
>NP_077024
          Length = 678

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RSPVVQNKL 9
           R PVV NK+
Sbjct: 592 RDPVVINKV 600
>XP_005259491
          Length = 293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  SPVVQNKL 9
          SPV  NKL
Sbjct: 71 SPVATNKL 78
>XP_005259490
          Length = 348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  SPVVQNKL 9
          SPV  NKL
Sbjct: 71 SPVATNKL 78
>XP_005267986
          Length = 2022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    RSPVVQNK 8
            RSP++ NK
Sbjct: 1544 RSPMMNNK 1551
>XP_006715118
          Length = 311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RSPVVQNK 8
           R PV+QN+
Sbjct: 304 RIPVIQNE 311
>XP_005264480
          Length = 1842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SPVVQNKL 9
            SPV+Q+K+
Sbjct: 1624 SPVLQHKI 1631
>XP_005264478
          Length = 1844

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SPVVQNKL 9
            SPV+Q+K+
Sbjct: 1626 SPVLQHKI 1633
>XP_005264475
          Length = 2027

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SPVVQNKL 9
            SPV+Q+K+
Sbjct: 1653 SPVLQHKI 1660
>XP_005277475
          Length = 1352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SPVVQNKL 9
           SP V+NKL
Sbjct: 204 SPGVENKL 211
>XP_005277474
          Length = 1414

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SPVVQNKL 9
           SP V+NKL
Sbjct: 278 SPGVENKL 285
>XP_006711546
          Length = 1426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SPVVQNKL 9
           SP V+NKL
Sbjct: 278 SPGVENKL 285
>XP_005273028
          Length = 1426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SPVVQNKL 9
           SP V+NKL
Sbjct: 278 SPGVENKL 285
>XP_005245421
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RSPVVQN 7
           ++PVVQN
Sbjct: 199 KTPVVQN 205
>XP_006711532
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RSPVVQN 7
           ++PVVQN
Sbjct: 199 KTPVVQN 205
>XP_005245420
          Length = 599

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RSPVVQN 7
           ++PVVQN
Sbjct: 205 KTPVVQN 211
>NP_277047
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RSPVVQNKL 9
           R+P  QNK+
Sbjct: 300 RNPYFQNKV 308
>NP_000292
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   PVVQNKL 9
           PV++NK+
Sbjct: 722 PVIENKV 728
>NP_003309
          Length = 857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RSPVVQN 7
           R+PVV+N
Sbjct: 467 RTPVVKN 473
>NP_001160163
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RSPVVQN 7
           R+PVV+N
Sbjct: 466 RTPVVKN 472
>NP_078966
          Length = 14507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1     RSPVVQ 6
             RSPV+Q
Sbjct: 10579 RSPVIQ 10584
>NP_001229725
          Length = 696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SPVVQNKL 9
           SP  +NKL
Sbjct: 241 SPATENKL 248
>NP_001229724
          Length = 696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SPVVQNKL 9
           SP  +NKL
Sbjct: 241 SPATENKL 248
>NP_055209
          Length = 345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SPVVQNKL 9
          SPVV+N +
Sbjct: 25 SPVVKNSI 32
>NP_055484
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SPVVQNKL 9
           SP  +NKL
Sbjct: 364 SPATENKL 371
>XP_006723004
          Length = 6443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    RSPVVQ 6
            RSPV+Q
Sbjct: 2493 RSPVIQ 2498
>XP_005256320
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SPVVQNKL 9
           SP  +NKL
Sbjct: 364 SPATENKL 371
>NP_001139669
          Length = 7081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    VVQNKL 9
            VVQNKL
Sbjct: 3849 VVQNKL 3854
>NP_001001919
          Length = 318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   RSPVVQNKL 9
           R P++ NK+
Sbjct: 131 RYPIIMNKV 139
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.128    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 726,830
Number of extensions: 1189
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package