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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_005253405                                                           17    4312
NP_777601                                                              17    4312
NP_055753                                                              16    5631
XP_006719356                                                           16    5631
XP_006719355                                                           16    5631
XP_006719354                                                           16    5631
XP_006719353                                                           16    5631
NP_057289                                                              16    7355
NP_056110                                                              16    7355
NP_002537                                                              16    7355
XP_005258159                                                           16    7355
XP_006722384                                                           16    7355
NP_976076                                                              15    9605
NP_000602                                                              15    9605
NP_976074                                                              15    9605
NP_001120695                                                           15    9605
NP_001120698                                                           15    9605
NP_001120699                                                           15    9605
NP_976075                                                              15    9605
NP_001120697                                                           15    9605
NP_005133                                                              15    9605
XP_005273967                                                           15    9605

>XP_005253405
          Length = 1463

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    SIFGMLLV 9
            SIFG+LL+
Sbjct: 1376 SIFGLLLL 1383



>NP_777601
          Length = 1453

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    SIFGMLLV 9
            SIFG+LL+
Sbjct: 1366 SIFGLLLL 1373



>NP_055753
          Length = 919

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RSIFGMLL 8
           RSIFG +L
Sbjct: 340 RSIFGSML 347



>XP_006719356
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RSIFGMLL 8
           RSIFG +L
Sbjct: 340 RSIFGSML 347



>XP_006719355
          Length = 920

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RSIFGMLL 8
           RSIFG +L
Sbjct: 340 RSIFGSML 347



>XP_006719354
          Length = 959

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RSIFGMLL 8
           RSIFG +L
Sbjct: 340 RSIFGSML 347



>XP_006719353
          Length = 960

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RSIFGMLL 8
           RSIFG +L
Sbjct: 340 RSIFGSML 347



>NP_057289
          Length = 345

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2 SIFGMLLV 9
         S+FG+LL+
Sbjct: 2 SLFGLLLL 9



>NP_056110
          Length = 2005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SIFGMLL 8
            ++FGMLL
Sbjct: 1825 TVFGMLL 1831



>NP_002537
          Length = 401

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SIFGMLL 8
           S+FG+LL
Sbjct: 167 SVFGLLL 173



>XP_005258159
          Length = 1817

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SIFGMLL 8
            ++FGMLL
Sbjct: 1637 TVFGMLL 1643



>XP_006722384
          Length = 1877

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SIFGMLL 8
            ++FGMLL
Sbjct: 1697 TVFGMLL 1703



>NP_976076
          Length = 128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  IFGMLLV 9
          +FG+LLV
Sbjct: 9  LFGLLLV 15



>NP_000602
          Length = 128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  IFGMLLV 9
          +FG+LLV
Sbjct: 9  LFGLLLV 15



>NP_976074
          Length = 128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  IFGMLLV 9
          +FG+LLV
Sbjct: 9  LFGLLLV 15



>NP_001120695
          Length = 128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  IFGMLLV 9
          +FG+LLV
Sbjct: 9  LFGLLLV 15



>NP_001120698
          Length = 128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  IFGMLLV 9
          +FG+LLV
Sbjct: 9  LFGLLLV 15



>NP_001120699
          Length = 128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  IFGMLLV 9
          +FG+LLV
Sbjct: 9  LFGLLLV 15



>NP_976075
          Length = 128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  IFGMLLV 9
          +FG+LLV
Sbjct: 9  LFGLLLV 15



>NP_001120697
          Length = 128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  IFGMLLV 9
          +FG+LLV
Sbjct: 9  LFGLLLV 15



>NP_005133
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RSIFGMLL 8
           RS+FG +L
Sbjct: 196 RSLFGQVL 203



>XP_005273967
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RSIFGMLL 8
           RS+FG +L
Sbjct: 171 RSLFGQVL 178



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.350    0.162    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 357,200
Number of extensions: 510
Number of successful extensions: 22
Number of sequences better than 10000.0: 22
Number of HSP's gapped: 22
Number of HSP's successfully gapped: 22
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)